ATP synthase subunit d, mitochondrial (P30902)

Identification
NameATP synthase subunit d, mitochondrial
SynonymsNot Available
Gene NameATP7
Enzyme ClassNot Available
Biological Properties
General FunctionInvolved in hydrogen ion transmembrane transporter acti
Specific FunctionMitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements
Cellular LocationMitochondrion. Mitochondrion inner membrane
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Component
mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
mitochondrial membrane part
cell part
membrane part
Function
ion transmembrane transporter activity
cation transmembrane transporter activity
inorganic cation transmembrane transporter activity
monovalent inorganic cation transmembrane transporter activity
hydrogen ion transmembrane transporter activity
transporter activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
Process
ATP synthesis coupled proton transport
nitrogen compound metabolic process
cellular nitrogen compound metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
nucleobase, nucleoside and nucleotide metabolic process
nucleoside phosphate metabolic process
metabolic process
nucleotide metabolic process
purine nucleotide metabolic process
purine nucleotide biosynthetic process
purine nucleoside triphosphate biosynthetic process
purine ribonucleoside triphosphate biosynthetic process
ATP biosynthetic process
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>525 bp ATGTCTTTGGCCAAATCCGCTGCTAACAAACTTGACTGGGCAAAAGTCATCTCTTCTCTA CGTATAACAGGGTCGACTGCCACTCAATTATCGAGTTTTAAAAAGAGAAACGATGAGGCA CGTAGACAATTACTAGAGCTGCAAAGTCAACCCACCGAAGTAGATTTCAGTCATTATAGA TCTGTGTTGAAAAACACTTCAGTCATTGACAAGATAGAATCATACGTTAAGCAATATAAG CCGGTCAAAATCGATGCCTCCAAACAATTACAAGTGATTGAGTCTTTTGAAAAGCACGCA ATGACCAACGCCAAGGAGACAGAATCCTTAGTTTCCAAGGAGTTAAAGGATTTGCAAAGC ACCTTAGATAATATTCAATCTGCAAGACCTTTCGATGAATTAACTGTTGACGACCTGACA AAGATCAAACCTGAAATTGATGCTAAGGTAGAAGAGATGGTCAAGAAGGGTAAATGGGAC GTACCTGGTTACAAGGACAGATTCGGCAATTTGAATGTGATGTAG
Protein Properties
Pfam Domain Function
Protein Residues174
Protein Molecular Weight19809.40039
Protein Theoretical pI9.56
Signalling Regions
  • None
Transmembrane Regions
  • None
Protein Sequence>ATP synthase subunit d, mitochondrial MSLAKSAANKLDWAKVISSLRITGSTATQLSSFKKRNDEARRQLLELQSQPTEVDFSHYR SVLKNTSVIDKIESYVKQYKPVKIDASKQLQVIESFEKHAMTNAKETESLVSKELKDLQS TLDNIQSARPFDELTVDDLTKIKPEIDAKVEEMVKKGKWDVPGYKDRFGNLNVM
References
External Links
ResourceLink
Saccharomyces Genome Database ATP7
Uniprot IDP30902
Uniprot NameATP7_YEAST
GenBank Gene IDAY558349
Genebank Protein ID45270588
General Reference
  • Norais, N., Prome, D., Velours, J. (1991). "ATP synthase of yeast mitochondria. Characterization of subunit d and sequence analysis of the structural gene ATP7." J Biol Chem 266:16541-16549.1832157
  • Wiemann, S., Voss, H., Schwager, C., Rupp, T., Stegemann, J., Zimmermann, J., Grothues, D., Sensen, C., Erfle, H., Hewitt, N., et, a. l. .. (1993). "Sequencing and analysis of 51.6 kilobases on the left arm of chromosome XI from Saccharomyces cerevisiae reveals 23 open reading frames including the FAS1 gene." Yeast 9:1343-1348.8154185
  • Dujon, B., Alexandraki, D., Andre, B., Ansorge, W., Baladron, V., Ballesta, J. P., Banrevi, A., Bolle, P. A., Bolotin-Fukuhara, M., Bossier, P., et, a. l. .. (1994). "Complete DNA sequence of yeast chromosome XI." Nature 369:371-378.8196765
  • Hu, Y., Rolfs, A., Bhullar, B., Murthy, T. V., Zhu, C., Berger, M. F., Camargo, A. A., Kelley, F., McCarron, S., Jepson, D., Richardson, A., Raphael, J., Moreira, D., Taycher, E., Zuo, D., Mohr, S., Kane, M. F., Williamson, J., Simpson, A., Bulyk, M. L., Harlow, E., Marsischky, G., Kolodner, R. D., LaBaer, J. (2007). "Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Genome Res 17:536-543.17322287
  • Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106