G2/mitotic-specific cyclin-1 (P24868)

Identification
NameG2/mitotic-specific cyclin-1
SynonymsNot Available
Gene NameCLB1
Enzyme ClassNot Available
Biological Properties
General Functionregulation of cyclin-dependent protein serine/threonine kinase activity
Specific FunctionEssential for the control of the cell cycle at the G2/M (mitosis) transition. Interacts with the CDC2 protein kinase to form MPF. G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: cell wall stress test 1PW007861 ThumbThumb?image type=greyscaleThumb?image type=simple
Stress-activated signalling pathways: high osmolarity test 1PW002773 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
meiotic G2/MI transition
mitotic spindle organization in nucleus
nucleus
cyclin-dependent protein kinase holoenzyme complex
cytoplasm
cell division
positive regulation of spindle pole body separation
mitotic nuclear division
cyclin-dependent protein serine/threonine kinase regulator activity
regulation of cyclin-dependent protein serine/threonine kinase activity
G2/M transition of mitotic cell cycle
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>1416 bp ATGTCACGATCCCTTTTGGTAGAGAATAGTAGAACCATTAATAGTAATGAAGAGAAGGGG GTAAACGAAAGTCAATATATCTTACAAAAGAGAAACGTCCCAAGGACCATTCTCGGTAAT GTCACAAATAATGCAAATATCCTGCAAGAGATTTCTATGAACAGAAAAATTGGGATGAAG AACTTCTCAAAATTGAACAACTTCTTTCCTTTAAAGGATGATGTTTCGAGAGCCGATGAC TTCACCTCCTCTTTTAATGACAGTAGACAGGGGGTGAAACAAGAAGTACTAAACAATAAG GAAAATATTCCTGAATATGGATATTCCGAGCAAGAAAAGCAGCAGTGCTCAAATGATGAC TCTTTTCATACGAATTCGACTGCCTTGAGCTGTAATCGGTTGATATACTCTGAGAACAAG TCTATTTCCACTCAAATGGAATGGCAGAAAAAAATAATGAGAGAAGATTCCAAAAAAAAA AGGCCAATATCAACTCTTGTAGAGCAGGATGACCAGAAAAAGTTCAAACTCCATGAATTG ACTACAGAAGAAGAGGTTCTGGAGGAGTACGAATGGGATGACCTAGATGAAGAAGATTGT GATGATCCCTTAATGGTGAGCGAAGAGGTTAATGATATCTTCGATTATTTGCATCACTTG GAAATAATCACATTGCCAAATAAGGCGAATCTCTATAAGCATAAAAATATTAAGCAAAAC AGAGACATTTTGGTGAACTGGATAATCAAGATTCATAATAAGTTTGGCCTTCTGCCGGAA ACTCTATATTTGGCCATAAACATAATGGATAGATTTCTTTGTGAAGAGGTGGTTCAGTTA AATAGATTGCAACTGGTTGGTACATCATGCCTGTTCATCGCATCTAAGTATGAGGAAATA TACTCCCCTAGCATAAAACATTTTGCGTACGAGACAGACGGTGCATGCTCTGTGGAAGAT ATTAAAGAGGGTGAAAGATTTATATTGGAAAAACTCGATTTTCAAATTAGTTTCGCTAAC CCAATGAATTTCTTAAGGAGAATATCAAAAGCGGATGACTATGATATCCAGTCTAGGACG TTAGCGAAGTTCCTAATGGAAATATCTATAGTGGACTTCAAGTTCATCGGGATATTACCG TCATTATGTGCCTCAGCGGCAATGTTCCTTTCGAGAAAAATGCTGGGCAAGGGCACCTGG GATGGCAACTTAATCCATTATAGTGGTGGTTACACAAAGGCAAAACTATATCCCGTTTGC CAATTACTGATGGATTATCTTGTTGGATCTACTATTCACGACGAGTTCTTGAAAAAATAT CAATCGAGAAGATTTTTAAAGGCTTCCATAATTTCTATCGAATGGGCATTGAAGGTAAGG AAAAATGGATATGATATTATGACATTGCATGAGTGA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues471
Protein Molecular Weight54869.99
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>G2/mitotic-specific cyclin-1 MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMK NFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDD SFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHEL TTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQN RDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEI YSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRT LAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVC QLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE
References
External Links
ResourceLink
Saccharomyces Genome Database CLB1
Uniprot IDP24868
Uniprot NameCLB1
General ReferenceNot Available