Cytochrome b-c1 complex subunit 9 (P22289)

Identification
NameCytochrome b-c1 complex subunit 9
Synonyms
  • Complex III subunit 9
  • Complex III subunit X
  • Cytochrome c1 non-heme 7.3 kDa protein
  • Ubiquinol-cytochrome c reductase complex 7.3 kDa protein
Gene NameQCR9
Enzyme ClassNot Available
Biological Properties
General FunctionInvolved in protein binding
Specific FunctionComponent of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain that generates an electrochemical potential coupled to ATP synthesis. The complex couples electron transfer from ubiquinol to cytochrome c. QCR9 is required for formation of a fully functional complex
Cellular LocationMitochondrion inner membrane
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Component
envelope
organelle envelope
mitochondrial envelope
cell part
Function
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
cation transmembrane transporter activity
inorganic cation transmembrane transporter activity
monovalent inorganic cation transmembrane transporter activity
hydrogen ion transmembrane transporter activity
ubiquinol-cytochrome-c reductase activity
transporter activity
Process
generation of precursor metabolites and energy
metabolic process
electron transport chain
respiratory electron transport chain
cellular metabolic process
mitochondrial electron transport, ubiquinol to cytochrome c
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>201 bp ATGTCTTTTTCATCACTATATAAAACCTTTTTCAAACGAAACGCTGTTTTTGTTGGTACT ATCTTTGCAGGTGCCTTTGTTTTCCAAACTGTATTTGATACTGCTATTACTTCATGGTAC GAGAATCACAACAAAGGAAAATTATGGAAAGATGTCAAGGCTCGAATAGCTGCAGGCGAT GGAGACGACGATGATGAGTAA
Protein Properties
Pfam Domain Function
Protein Residues66
Protein Molecular Weight7476.2998
Protein Theoretical pI5.75
PDB Fileshow
Signalling Regions
  • None
Transmembrane Regions
  • 16-37
Protein Sequence>Cytochrome b-c1 complex subunit 9 MSFSSLYKTFFKRNAVFVGTIFAGAFVFQTVFDTAITSWYENHNKGKLWKDVKARIAAGD GDDDDE
References
External Links
ResourceLink
Saccharomyces Genome Database QCR9
Uniprot IDP22289
Uniprot NameQCR9_YEAST
GenBank Gene IDM59797
Genebank Protein ID172312
PDB ID
1KYO
General Reference
  • Phillips, J. D., Schmitt, M. E., Brown, T. A., Beckmann, J. D., Trumpower, B. L. (1990). "Isolation and characterization of QCR9, a nuclear gene encoding the 7.3-kDa subunit 9 of the Saccharomyces cerevisiae ubiquinol-cytochrome c oxidoreductase complex. An intron-containing gene with a conserved sequence occurring in the intron of COX4." J Biol Chem 265:20813-20821.2174427
  • Arroyo, J., Garcia-Gonzalez, M., Garcia-Saez, M. I., Sanchez, M., Nombela, C. (1997). "DNA sequence analysis of a 23,002 bp DNA fragment of the right arm of Saccharomyces cerevisiae chromosome VII." Yeast 13:357-363.9133739
  • Tettelin, H., Agostoni Carbone, M. L., Albermann, K., Albers, M., Arroyo, J., Backes, U., Barreiros, T., Bertani, I., Bjourson, A. J., Bruckner, M., Bruschi, C. V., Carignani, G., Castagnoli, L., Cerdan, E., Clemente, M. L., Coblenz, A., Coglievina, M., Coissac, E., Defoor, E., Del Bino, S., Delius, H., Delneri, D., de Wergifosse, P., Dujon, B., Kleine, K., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII." Nature 387:81-84.9169869
  • Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106
  • Hunte, C., Koepke, J., Lange, C., Rossmanith, T., Michel, H. (2000). "Structure at 2.3 A resolution of the cytochrome bc(1) complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment." Structure 8:669-684.10873857
  • Lange, C., Hunte, C. (2002). "Crystal structure of the yeast cytochrome bc1 complex with its bound substrate cytochrome c." Proc Natl Acad Sci U S A 99:2800-2805.11880631