Cytochrome P450-DIT2 (P21595)

Identification
NameCytochrome P450-DIT2
Synonyms
  • Cytochrome P450 56
Gene NameDIT2
Enzyme ClassNot Available
Biological Properties
General FunctionSecondary metabolites biosynthesis, transport and catabolism
Specific FunctionInvolved in spore wall maturation. Thought to catalyze the oxidation of tyrosine residues in the formation of LL- dityrosine a precursor of the spore wall
Cellular LocationNot Available
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
oxidoreductase activity
heme binding
electron carrier activity
iron ion binding
monooxygenase activity
binding
ion binding
cation binding
metal ion binding
transition metal ion binding
catalytic activity
Process
oxidation reduction
metabolic process
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>1470 bp ATGGAGTTGTTAAAGCTTCTGTGTTTGATTTTATTTCTTACTCTTTCCTATGTCGCCTTT GCAATCATTGTCCCACCTCTAAACTTTCCCAAAAATATACCCACCATCCCATTTTATGTA GTATTTTTACCAGTAATATTTCCCATTGATCAAACGGAGCTATACGATCTTTATATTAGG GAATCAATGGAAAAATACGGTGCTGTAAAATTTTTCTTTGGTTCACGGTGGAATATTCTC GTTTCTCGTTCTGAGTATCTAGCACAAATATTCAAAGATGAAGATACTTTTGCGAAGAGC GGTAATCAAAAGAAAATCCCATACAGTGCTCTTGCCGCTTACACAGGGGACAATGTCATT AGCGCGTATGGTGCAGTTTGGAGAAACTACAGAAATGCTGTGACAAACGGGCTCCAACAT TTTGACGATGCACCTATATTCAAAAATGCAAAAATTTTATGCACTTTGATAAAAAACAGA CTCCTAGAAGGACAAACTTCGATCCCTATGGGACCTTTATCCCAGAGAATGGCATTGGAT AACATTTCACAGGTTGCCCTTGGATTTGATTTTGGTGCTCTAACACATGAAAAAAATGCT TTCCACGAGCATTTGATTCGTATTAAAAAGCAAATATTTCATCCATTCTTTTTAACTTTT CCATTCCTTGATGTTCTTCCTATTCCTTCAAGAAAAAAAGCCTTCAAGGATGTTGTTAGT TTTAGAGAACTTCTCGTTAAAAGAGTTCAAGATGAATTAGTCAATAATTACAAATTTGAA CAAACTACTTTTGCTGCCAGTGATCTAATTCGTGCTCACAATAACGAAATAATCGACTAC AAACAGTTGACCGATAATATCGTCATTATCCTTGTCGCTGGCCATGAAAACCCGCAGTTG CTATTTAATAGTTCACTCTACCTTCTAGCCAAATATTCAAATGAATGGCAAGAGAAACTC AGGAAGGAAGTAAACGGCATCACTGATCCAAAAGGCTTAGCAGATTTACCCTTATTAAAT GCTTTTCTCTTCGAAGTAGTAAGAATGTATCCTCCTTTGAGCACAATTATTAATAGATGT ACTACCAAAACGTGCAAGTTGGGGGCGGAAATTGTTATACCCAAGGGCGTATATGTCGGG TACAACAACTTTGGAACCTCACACGATCCCAAAACTTGGGGCACAACAGCAGATGATTTT AAACCAGAAAGATGGGGTTCAGATATCGAAACCATAAGGAAAAACTGGAGAATGGCGAAA AACAGATGTGCTGTGACTGGGTTCCATGGAGGCCGAAGAGCATGCCTAGGGGAAAAACTA GCCCTAACAGAAATGAGAATTTCTTTGGCTGAAATGTTGAAACAGTTTCGATGGAGTCTT GACCCTGAATGGGAAGAAAAATTAACTCCCGCTGGGCCTCTTTGCCCTCTTAATTTAAAG TTAAAATTTAACGAGAATATAATGGAATAA
Protein Properties
Pfam Domain Function
Protein Residues489
Protein Molecular Weight56070.69922
Protein Theoretical pI9.02
Signalling Regions
  • None
Transmembrane Regions
  • None
Protein Sequence>Cytochrome P450-DIT2 MELLKLLCLILFLTLSYVAFAIIVPPLNFPKNIPTIPFYVVFLPVIFPIDQTELYDLYIR ESMEKYGAVKFFFGSRWNILVSRSEYLAQIFKDEDTFAKSGNQKKIPYSALAAYTGDNVI SAYGAVWRNYRNAVTNGLQHFDDAPIFKNAKILCTLIKNRLLEGQTSIPMGPLSQRMALD NISQVALGFDFGALTHEKNAFHEHLIRIKKQIFHPFFLTFPFLDVLPIPSRKKAFKDVVS FRELLVKRVQDELVNNYKFEQTTFAASDLIRAHNNEIIDYKQLTDNIVIILVAGHENPQL LFNSSLYLLAKYSNEWQEKLRKEVNGITDPKGLADLPLLNAFLFEVVRMYPPLSTIINRC TTKTCKLGAEIVIPKGVYVGYNNFGTSHDPKTWGTTADDFKPERWGSDIETIRKNWRMAK NRCAVTGFHGGRRACLGEKLALTEMRISLAEMLKQFRWSLDPEWEEKLTPAGPLCPLNLK LKFNENIME
References
External Links
ResourceLink
Saccharomyces Genome Database DIT2
Uniprot IDP21595
Uniprot NameCP56_YEAST
GenBank Gene IDU32274
Genebank Protein ID927333
General Reference
  • Briza, P., Breitenbach, M., Ellinger, A., Segall, J. (1990). "Isolation of two developmentally regulated genes involved in spore wall maturation in Saccharomyces cerevisiae." Genes Dev 4:1775-1789.2249774
  • Jacq, C., Alt-Morbe, J., Andre, B., Arnold, W., Bahr, A., Ballesta, J. P., Bargues, M., Baron, L., Becker, A., Biteau, N., Blocker, H., Blugeon, C., Boskovic, J., Brandt, P., Bruckner, M., Buitrago, M. J., Coster, F., Delaveau, T., del Rey, F., Dujon, B., Eide, L. G., Garcia-Cantalejo, J. M., Goffeau, A., Gomez-Peris, A., Zaccaria, P., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV." Nature 387:75-78.9169867
  • Briza, P., Eckerstorfer, M., Breitenbach, M. (1994). "The sporulation-specific enzymes encoded by the DIT1 and DIT2 genes catalyze a two-step reaction leading to a soluble LL-dityrosine-containing precursor of the yeast spore wall." Proc Natl Acad Sci U S A 91:4524-4528.8183942