{"ymdb_id":"YMDB16331","created_at":"2016-09-12T18:37:11.000Z","updated_at":"2016-10-17T22:34:45.000Z","name":"1-O-Hexadecyl-2-palmitoyl-sn-glycerol","cas":null,"state":null,"melting_point":null,"description":null,"experimental_water_solubility":null,"experimental_logp_hydrophobicity":null,"location":null,"synthesis_reference":null,"chebi_id":null,"hmdb_id":null,"kegg_id":null,"pubchem_id":null,"cs_id":null,"foodb_id":null,"wikipedia_link":null,"biocyc_id":null,"iupac":"hexadecyloxy hydroxy hexadecanoate","traditional_iupac":"hexadecyloxy hydroxy hexadecanoate","logp":null,"pka":null,"alogps_solubility":"1.44e-05 g/l","alogps_logp":"10.33","alogps_logs":"-7.55","acceptor_count":"0","donor_count":"0","rotatable_bond_count":"31","polar_surface_area":"60.120000000000005","refractivity":"166.6178","polarizability":"69.60672772410456","formal_charge":"0","physiological_charge":"0","pka_strongest_basic":null,"pka_strongest_acidic":null,"bioavailability":"0","number_of_rings":"0","rule_of_five":"0","ghose_filter":"0","veber_rule":"0","mddr_like_rule":"0","synonyms":[],"pathways":[{"name":"Ether lipid metabolism","kegg_map_id":"00565"}],"growth_conditions":[],"references":[],"proteins":[{"created_at":"2011-05-26T18:07:16.000Z","updated_at":"2011-07-22T17:54:27.000Z","name":"Cholinephosphotransferase 1","uniprot_id":"P17898","uniprot_name":"CPT1_YEAST","enzyme":true,"transporter":false,"gene_name":"CPT1","num_residues":393,"molecular_weight":"44829.0","theoretical_pi":"6.57","general_function":"Involved in phosphotransferase activity, for other substituted phosphate groups","specific_function":"Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface. The multiple transmembrane domains and lumenal hydrophilic domains of the cholinephosphotransferase might participate in the transport process","reactions":[{"id":1386,"direction":"\u003c\u003e","locations":"endoplasmic reticulum","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1387,"direction":"\u003e","locations":"endoplasmic reticulum","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":2507,"direction":"\u003e","locations":"Microsome membrane; Multi-pass membrane protein; Multi-pass membrane protein. Endoplasmic reticulum membrane","altext":"CDP-choline + 1,2-diacylglycerol = CMP + a phosphatidylcholine.","export":false,"pw_reaction_id":null,"source":null},{"id":14462,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006981","source":"Smpdb"},{"id":14463,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006984","source":"Smpdb"},{"id":14464,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R007002","source":"Smpdb"},{"id":14465,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R047264","source":"Smpdb"},{"id":14466,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R047316","source":"Smpdb"},{"id":14467,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R047322","source":"Smpdb"},{"id":14468,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R047327","source":"Smpdb"},{"id":14469,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R047333","source":"Smpdb"},{"id":14470,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R047339","source":"Smpdb"},{"id":14471,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R047344","source":"Smpdb"},{"id":14472,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R047350","source":"Smpdb"}],"signal_regions":"None","transmembrane_regions":"41-61;173-193;211-231;264-284;286-306;321-341;349-369","pdb_id":null,"cellular_location":"Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein","genbank_gene_id":"J05203","genbank_protein_id":"171318","gene_card_id":"CPT1","chromosome_location":"chromosome 14","locus":"YNL130C","synonyms":["Diacylglycerol cholinephosphotransferase 1","Sn-1,2-diacylglycerol cholinephosphotransferase","CHOPT"],"enzyme_classes":["2.7.8.2"],"go_classes":[{"category":"Component","description":" cell part"},{"category":"Component","description":" membrane"},{"category":"Function","description":" catalytic activity"},{"category":"Function","description":" transferase activity"},{"category":"Function","description":" transferase activity, transferring phosphorus-containing groups"},{"category":"Function","description":" phosphotransferase activity, for other substituted phosphate groups"},{"category":"Process","description":" phospholipid metabolic process"},{"category":"Process","description":" phospholipid biosynthetic process"},{"category":"Process","description":" metabolic process"},{"category":"Process","description":" organophosphate metabolic process"}],"pfams":[{"name":"CDP-OH_P_transf","identifier":"PF01066"}],"pathways":[{"name":"Glycerophospholipid metabolism","kegg_map_id":"00564"},{"name":"Ether lipid metabolism","kegg_map_id":"00565"},{"name":"Choline metabolism","kegg_map_id":null},{"name":"Lysolipid incorporation into ER","kegg_map_id":null},{"name":"Lysolipid incorporation into ER PC(10:0/10:0)","kegg_map_id":null},{"name":"Lysolipid incorporation into ER PC(14:0/14:0)","kegg_map_id":null},{"name":"Lysolipid incorporation into ER PC(16:0/16:0)","kegg_map_id":null},{"name":"Lysolipid incorporation into ER PC(16:1(11Z)/16:1(11Z))","kegg_map_id":null},{"name":"Lysolipid incorporation into ER PC(16:1(9Z)/16:1(9Z))","kegg_map_id":null},{"name":"Lysolipid incorporation into ER PC(18:0/18:0)","kegg_map_id":null},{"name":"Lysolipid incorporation into ER PC(18:1(9Z)/18:1(9Z))","kegg_map_id":null},{"name":"Lysolipid incorporation into ER PC(18:2(9Z,11Z)/18:2(9Z,11Z))","kegg_map_id":null},{"name":"Lysolipid incorporation into ER PC(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z))","kegg_map_id":null}],"gene_sequence":"ATGGATTCGAAAACAGTATTACTAACTGATTCAGGGGAAACAATGGGATTCTTTATTCCTCAGAGTAGTTTGGGAAACTTGAAGCTTTACAAGTATCAAAGTGATGACCGCTCTTTCCTTTCAAACCATGTATTGAGGCCCTTTTGGAGAAAGTTTGCGACTATTTTTCCACTATGGATGGCACCCAATTTGGTAACATTATTAGGGTTCTGCTTTATTATATTTAATGTGTTAACAACACTTTACTACGACCCGTATTTTGACCAGGAATCGCCACGTTGGACCTATTTCTCCTATGCTATAGGTTTGTTTTTATACCAGACTTTTGATGCTTGCGATGGAATGCATGCACGTCGTACAGGCCAGCAGGGCCCTCTAGGGGAATTGTTTGACCATTGTATTGATTCAATCAACACAACTTTGTCAATGATTCCTGTCTGTTCCATGACAGGTATGGGTTACACATATATGACCATTTTTTCACAATTTGCGATATTGTGCAGCTTTTACTTGAGCACATGGGAAGAGTATCACACCCACAAACTTTATCTAGCTGAATTCTGCGGTCCTGTTGAAGGTATTATTGTTTTGTGTATTTCTTTCATTGCAGTCGGAATTTACGGACCTCAAACCATCTGGCACACTAAAGTAGCGCAATTCTCCTGGCAAGATTTTGTGTTTGATGTTGAAACCGTTCATCTAATGTATGCATTTTGCACAGGAGCATTAATATTTAATATTGTCACAGCTCATACAAACGTCGTGAGGTATTACGAATCCCAATCGACCAAATCTGCAACTCCAAGCAAAACTGCAGAAAATATAAGTAAAGCAGTAAATGGTCTTTTGCCATTCTTTGCATACTTCTCTTCAATTTTTACCTTAGTCTTGATTCAACCATCTTTTATTTCTTTGGCTTTAATTTTATCGATTGGTTTTTCGGTTGCCTTTGTAGTTGGTCGGATGATTATTGCTCATTTAACCATGCAACCATTCCCAATGGTCAATTTCCCATTTTTAATCCCAACTATCCAATTGGTATTGTACGCATTTATGGTTTACGTTTTAGATTACCAAAAAGGAAGCATAGTTTCTGCATTGGTTTGGATGGGACTCGGCTTGACACTTGCTATCCATGGAATGTTCATCAATGATATTATCTATGACATCACTACCTTTCTGGATATTTACGCTTTATCAATTAAACATCCAAAAGAAATTTAG","protein_sequence":"MGFFIPQSSLGNLKLYKYQSDDRSFLSNHVLRPFWRKFATIFPLWMAPNLVTLLGFCFIIFNVLTTLYYDPYFDQESPRWTYFSYAIGLFLYQTFDACDGMHARRTGQQGPLGELFDHCIDSINTTLSMIPVCSMTGMGYTYMTIFSQFAILCSFYLSTWEEYHTHKLYLAEFCGPVEGIIVLCISFIAVGIYGPQTIWHTKVAQFSWQDFVFDVETVHLMYAFCTGALIFNIVTAHTNVVRYYESQSTKSATPSKTAENISKAVNGLLPFFAYFSSIFTLVLIQPSFISLALILSIGFSVAFVVGRMIIAHLTMQPFPMVNFPFLIPTIQLVLYAFMVYVLDYQKGSIVSALVWMGLGLTLAIHGMFINDIIYDITTFLDIYALSIKHPKEI"},{"created_at":"2016-09-09T22:51:49.000Z","updated_at":"2016-09-09T22:51:49.000Z","name":"Ethanolaminephosphotransferase 1","uniprot_id":"Q9C0D9","uniprot_name":null,"enzyme":false,"transporter":false,"gene_name":null,"num_residues":null,"molecular_weight":null,"theoretical_pi":null,"general_function":null,"specific_function":null,"reactions":[{"id":14475,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006985","source":"Smpdb"},{"id":14476,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006994","source":"Smpdb"}],"signal_regions":null,"transmembrane_regions":null,"pdb_id":null,"cellular_location":null,"genbank_gene_id":null,"genbank_protein_id":null,"gene_card_id":null,"chromosome_location":null,"locus":null,"synonyms":["hEPT1","Selenoprotein I","SelI"],"enzyme_classes":[],"go_classes":[{"category":"Function","description":"metal ion binding"},{"category":"Function","description":"integral component of membrane"},{"category":"Function","description":"endoplasmic reticulum membrane"},{"category":"Function","description":"ethanolaminephosphotransferase activity"},{"category":"Function","description":"phosphatidylethanolamine biosynthetic process"},{"category":"Function","description":"positive regulation of protein targeting to mitochondrion"}],"pfams":[],"pathways":[{"name":"Ether lipid metabolism","kegg_map_id":"00565"},{"name":"Glycerophospholipid metabolism","kegg_map_id":"00564"}],"gene_sequence":null,"protein_sequence":null}]}