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Implicated in the defense against oxidative stress","reactions":[{"id":2812,"direction":"\u003e","locations":"Cytoplasm;Mitochondrion","altext":"Thioredoxin + NADP(+) = thioredoxin disulfide + NADPH.","export":false,"pw_reaction_id":null,"source":null},{"id":14298,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006795","source":"Smpdb"}],"signal_regions":"None","transmembrane_regions":"None","pdb_id":null,"cellular_location":"Mitochondrion","genbank_gene_id":"AY557882","genbank_protein_id":"45269655","gene_card_id":"TRR2","chromosome_location":"chromosome 8","locus":"YHR106W","synonyms":[],"enzyme_classes":["1.8.1.9"],"go_classes":[{"category":"Component","description":" intracellular part"},{"category":"Component","description":" cytoplasm"},{"category":"Component","description":" cell part"},{"category":"Function","description":" nucleoside binding"},{"category":"Function","description":" purine nucleoside binding"},{"category":"Function","description":" adenyl nucleotide binding"},{"category":"Function","description":" FAD or FADH2 binding"},{"category":"Function","description":" oxidoreductase activity"},{"category":"Function","description":" antioxidant activity"},{"category":"Function","description":" catalytic activity"},{"category":"Function","description":" thioredoxin-disulfide reductase activity"},{"category":"Function","description":" binding"},{"category":"Process","description":" oxidation reduction"},{"category":"Process","description":" oxygen and reactive oxygen species metabolic process"},{"category":"Process","description":" superoxide metabolic process"},{"category":"Process","description":" metabolic process"},{"category":"Process","description":" removal of superoxide radicals"},{"category":"Process","description":" cellular metabolic process"}],"pfams":[{"name":"Pyr_redox","identifier":"PF00070"},{"name":"Pyr_redox_2","identifier":"PF07992"}],"pathways":[{"name":"Pyrimidine metabolism","kegg_map_id":"00240"},{"name":"Selenocompound metabolism","kegg_map_id":"00450"}],"gene_sequence":"ATGATAAAACATATAGTTTCGCCATTCAGGACGAATTTTGTTGGCATCAGCAAGTCCGTGCTGTCAAGGATGATTCATCACAAGGTTACAATCATAGGTTCTGGCCCCGCTGCCCACACCGCTGCTATATACTTGGCAAGAGCAGAGATGAAGCCCACATTATATGAGGGAATGATGGCCAACGGAATTGCTGCTGGTGGCCAATTGACAACAACCACCGATATCGAAAATTTCCCAGGGTTTCCTGAATCGTTGAGTGGCAGTGAACTGATGGAGAGGATGAGGAAACAATCTGCCAAGTTTGGCACTAACATAATTACCGAGACTGTCTCTAAAGTCGATTTATCTTCAAAACCATTCAGATTATGGACCGAATTTAATGAGGATGCAGAGCCTGTGACCACTGATGCTATAATCTTGGCCACGGGTGCTTCCGCTAAGAGAATGCATTTACCAGGGGAGGAAACCTACTGGCAGCAGGGAATATCTGCCTGTGCTGTATGTGATGGTGCAGTCCCTATCTTTAGAAACAAGCCATTGGCCGTTATTGGTGGTGGTGACTCTGCGTGTGAGGAAGCGGAATTTCTTACGAAGTATGCGTCGAAAGTATATATATTAGTAAGAAAGGATCATTTTCGTGCATCTGTAATAATGCAGAGACGAATTGAGAAAAATCCAAACATCATTGTTTTGTTCAACACAGTTGCATTAGAAGCTAAGGGTGATGGTAAGTTATTGAATATGTTGAGAATTAAGAATACTAAAAGTAATGTGGAGAACGATTTAGAAGTAAATGGACTATTTTACGCAATAGGTCACAGCCCTGCCACAGATATAGTTAAAGGACAAGTAGATGAAGAAGAGACGGGGTATATAAAAACTGTGCCTGGATCGTCTCTGACTTCTGTGCCAGGTTTTTTTGCTGCAGGTGACGTTCAGGACTCTAGGTATAGACAAGCAGTTACTTCTGCTGGTTCCGGATGCATTGCTGCTTTGGATGCAGAACGGTACCTAAGTGCCCAAGAGTAA","protein_sequence":"MIKHIVSPFRTNFVGISKSVLSRMIHHKVTIIGSGPAAHTAAIYLARAEMKPTLYEGMMANGIAAGGQLTTTTDIENFPGFPESLSGSELMERMRKQSAKFGTNIITETVSKVDLSSKPFRLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQQGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAEFLTKYASKVYILVRKDHFRASVIMQRRIEKNPNIIVLFNTVALEAKGDGKLLNMLRIKNTKSNVENDLEVNGLFYAIGHSPATDIVKGQVDEEETGYIKTVPGSSLTSVPGFFAAGDVQDSRYRQAVTSAGSGCIAALDAERYLSAQE"}]}