{"ymdb_id":"YMDB16136","created_at":"2016-09-12T18:14:08.000Z","updated_at":"2016-10-17T22:34:41.000Z","name":"D-Myo-inositol 4-phosphate","cas":null,"state":"Solid","melting_point":null,"description":null,"experimental_water_solubility":null,"experimental_logp_hydrophobicity":null,"location":null,"synthesis_reference":null,"chebi_id":null,"hmdb_id":null,"kegg_id":null,"pubchem_id":null,"cs_id":null,"foodb_id":null,"wikipedia_link":null,"biocyc_id":null,"iupac":"{[(1S,2R,3S,4S,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphonic acid","traditional_iupac":"myo-inositol 4-phosphate","logp":"-3.9055756833333333","pka":"6.194111788919007","alogps_solubility":"3.95e+01 g/l","alogps_logp":"-1.98","alogps_logs":"-0.82","acceptor_count":"8","donor_count":"7","rotatable_bond_count":"2","polar_surface_area":"167.91","refractivity":"46.64789999999999","polarizability":"20.563720024288987","formal_charge":"0","physiological_charge":"-2","pka_strongest_basic":"-3.645813019693807","pka_strongest_acidic":"1.1625722061585555","bioavailability":"1","number_of_rings":"1","rule_of_five":"0","ghose_filter":"0","veber_rule":"0","mddr_like_rule":"0","synonyms":[],"pathways":[{"name":"Inositol Metabolism","kegg_map_id":null}],"growth_conditions":[],"references":[],"proteins":[{"created_at":"2011-05-29T04:10:26.000Z","updated_at":"2011-05-29T05:06:53.000Z","name":"Inositol monophosphatase 1","uniprot_id":"P38710","uniprot_name":"INM1_YEAST","enzyme":true,"transporter":false,"gene_name":"INM1","num_residues":295,"molecular_weight":"32823.0","theoretical_pi":"4.92","general_function":"Involved in inositol or phosphatidylinositol phosphatase activity","specific_function":"Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides","reactions":[{"id":1749,"direction":"\u003e","locations":"cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":2708,"direction":"\u003e","locations":"Cytoplasm. Nucleus;Cytoplasmic","altext":"Myo-inositol phosphate + H(2)O = myo-inositol + phosphate.","export":false,"pw_reaction_id":null,"source":null},{"id":14846,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R007023","source":"Smpdb"},{"id":14847,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R007024","source":"Smpdb"},{"id":14848,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R007027","source":"Smpdb"},{"id":14849,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R007040","source":"Smpdb"}],"signal_regions":"None","transmembrane_regions":"None","pdb_id":null,"cellular_location":"Cytoplasm. Nucleus","genbank_gene_id":null,"genbank_protein_id":null,"gene_card_id":"INM1","chromosome_location":"chromosome 8","locus":"YHR046C","synonyms":["IMP 1","IMPase 1","Inositol-1(or 4)-monophosphatase 1"],"enzyme_classes":["3.1.3.25"],"go_classes":[{"category":"Component","description":" Not Available"},{"category":"Function","description":" catalytic activity"},{"category":"Function","description":" hydrolase activity"},{"category":"Function","description":" hydrolase activity, acting on ester bonds"},{"category":"Function","description":" phosphoric ester hydrolase activity"},{"category":"Function","description":" phosphatase activity"},{"category":"Function","description":" inositol or phosphatidylinositol phosphatase activity"},{"category":"Process","description":" Not Available"}],"pfams":[{"name":"Inositol_P","identifier":"PF00459"}],"pathways":[{"name":"Inositol phosphate metabolism","kegg_map_id":"00562"},{"name":"Inositol Metabolism","kegg_map_id":null}],"gene_sequence":"ATGACCATTGATCTAGCTTCTATCGAGAAATTCCTCTGTGAACTGGCTACTGAAAAAGTAGGACCAATCATCAAATCCAAGTCCGGCACTCAAAAGGATTATGACTTGAAGACTGGCTCCAGGAGCGTTGATATTGTAACTGCTATCGATAAACAGGTCGAAAAGTTAATTTGGGAATCGGTAAAAACCCAATATCCAACTTTCAAGTTTATTGGAGAGGAAAGTTATGTGAAAGGGGAGACCGTGATTACTGATGATCCTACCTTTATTATTGATCCAATTGATGGGACTACAAACTTTGTTCATGATTTCCCATTTAGCTGTACCTCTCTTGGGCTCACAGTAAACAAAGAGCCCGTAGTAGGCGTTATATATAATCCTCACATTAATCTTCTGGTATCCGCTTCTAAAGGAAATGGGATGAGAGTTAACAACAAGGACTATGACTATAAATCAAAATTGGAATCTATGGGTTCTCTAATACTAAATAAATCCGTAGTGGCATTACAGCCAGGTTCCGCTAGAGAGGGAAAGAATTTTCAGACAAAAATGGCCACATATGAAAAATTACTATCATGTGATTACGGTTTTGTTCATGGATTCAGAAATTTAGGATCATCTGCAATGACAATGGCATATATTGCTATGGGGTACCTTGATAGTTATTGGGATGGTGGTTGCTATTCGTGGGACGTGTGTGCTGGATGGTGTATTTTGAAAGAAGTGGGCGGTCGTGTAGTAGGTGCCAATCCAGGTGAATGGAGTATTGATGTCGACAATAGGACATATTTGGCTGTGAGGGGAACAATTAATAACGAAAGTGACGAACAAACAAAATATATCACAGACTTTTGGAACTGTGTTGATGGCCATTTGAAATATGACTGA","protein_sequence":"MTIDLASIEKFLCELATEKVGPIIKSKSGTQKDYDLKTGSRSVDIVTAIDKQVEKLIWESVKTQYPTFKFIGEESYVKGETVITDDPTFIIDPIDGTTNFVHDFPFSCTSLGLTVNKEPVVGVIYNPHINLLVSASKGNGMRVNNKDYDYKSKLESMGSLILNKSVVALQPGSAREGKNFQTKMATYEKLLSCDYGFVHGFRNLGSSAMTMAYIAMGYLDSYWDGGCYSWDVCAGWCILKEVGGRVVGANPGEWSIDVDNRTYLAVRGTINNESDEQTKYITDFWNCVDGHLKYD"}]}