{"ymdb_id":"YMDB14523","created_at":"2016-07-07T23:31:45.000Z","updated_at":"2016-10-17T22:39:53.000Z","name":"PGP(18:1(9Z)/22:0)","cas":null,"state":"Solid","melting_point":null,"description":"PGP(18:1(9Z)/22:0) belongs to the class of glycerophosphoglycerophosphates, also called phosphatidylglycerophosphates (PGPs). These lipids contain a common glycerophosphate skeleton linked to at least one fatty acyl chain and a glycero-3-phosphate moiety. As is the case with diacylglycerols, phosphatidylglycerophosphates can have many different combinations of fatty acids of varying lengths and saturation attached to the C-1 and C-2 positions. PGP(18:1(9Z)/22:0), in particular, consists of one 9Z-octadecenoyl chain  to the C-1 atom, and one docosanoyl  to the C-2 atom. In E. coli, PGPs can be found in the cytoplasmic membrane. The are synthesized by the addition of glycerol 3-phosphate to a CDP-diacylglycerol. In turn, PGPs are dephosphorylated to Phosphatidylglycerols (PGs) by the enzyme Phosphatidylglycerophosphatase.","experimental_water_solubility":null,"experimental_logp_hydrophobicity":null,"location":"Mitochondrion membrane","synthesis_reference":null,"chebi_id":null,"hmdb_id":null,"kegg_id":null,"pubchem_id":null,"cs_id":null,"foodb_id":null,"wikipedia_link":null,"biocyc_id":null,"iupac":"[(2S)-3-({[(2R)-2-(docosanoyloxy)-3-[(9Z)-octadec-9-enoyloxy]propoxy](hydroxy)phosphoryl}oxy)-2-hydroxypropoxy]phosphonic acid","traditional_iupac":"(2S)-3-{[(2R)-2-(docosanoyloxy)-3-[(9Z)-octadec-9-enoyloxy]propoxy(hydroxy)phosphoryl]oxy}-2-hydroxypropoxyphosphonic acid","logp":"14.008113151333333","pka":"2.0402061436989327","alogps_solubility":"3.65e-04 g/l","alogps_logp":"8.17","alogps_logs":"-6.40","acceptor_count":"8","donor_count":"4","rotatable_bond_count":"49","polar_surface_area":"195.34999999999997","refractivity":"244.10640000000004","polarizability":"108.65550737340398","formal_charge":"0","physiological_charge":"-3","pka_strongest_basic":"-3.410499386302644","pka_strongest_acidic":"1.354879296415124","bioavailability":"0","number_of_rings":"0","rule_of_five":"0","ghose_filter":"0","veber_rule":"0","mddr_like_rule":"0","synonyms":[],"pathways":[],"growth_conditions":[],"references":[{"pubmed_id":240350,"citation":"Rattray JB, Schibeci A, Kidby DK. (1975). \"Lipids of yeasts.\" Bacteriol Rev. 1975 Sep;39(3):197-231."}],"proteins":[]}