{"ymdb_id":"YMDB01774","created_at":"2011-08-31T03:44:06.000Z","updated_at":"2016-09-08T18:37:07.000Z","name":"Phenyllactic acid","cas":"515-30-0","state":"Solid","melting_point":"98 oC","description":"Phenyllactic acid (PLA) is an antifungal metabolite produced by lactic acid bacteria (LAB). Lactic acid bacteria are naturally associated with many foods or their raw ingredients and are popularly used in food fermentation to enhance the sensory, aromatic, and textural properties of food. These microorganisms are well recognized for their biopreservative properties, which are achieved through the production of antimicrobial compounds such as lactic acid, diacetyl, bacteriocins, and other metabolites. [PMID 18724772]","experimental_water_solubility":"21.2 mg/mL at 25 oC [MERCK INDEX (1996)]","experimental_logp_hydrophobicity":"1.83 [HANSCH,C ET AL. (1995)]","location":null,"synthesis_reference":null,"chebi_id":"16684","hmdb_id":"HMDB00779","kegg_id":"C01479","pubchem_id":"643327","cs_id":"1263","foodb_id":null,"wikipedia_link":null,"biocyc_id":null,"iupac":"2-hydroxy-2-phenylpropanoic acid","traditional_iupac":"(+-)-atrolactic acid","logp":"1.328601530666666","pka":"13.436954173717783","alogps_solubility":"1.97e+01 g/l","alogps_logp":"1.07","alogps_logs":"-0.93","acceptor_count":"3","donor_count":"2","rotatable_bond_count":"2","polar_surface_area":"57.53","refractivity":"43.4171","polarizability":"16.491249237127427","formal_charge":"0","physiological_charge":"-1","pka_strongest_basic":"-4.152792869743224","pka_strongest_acidic":"3.812777970192769","bioavailability":"1","number_of_rings":"1","rule_of_five":"1","ghose_filter":"1","veber_rule":"0","mddr_like_rule":"0","synonyms":["2-Hydroxy-2-phenylpropanoic acid","2-Hydroxy-2-phenylpropionic acid","2-Phenyl-2-hydroxypropionic acid","2-Phenyllactic acid","alpha-Hydroxy-alpha-phenylpropionic acid","alpha-Phenyllactic acid","dl-Atrolactic acid","Mandelic acid, .alpha.-methyl-","Mandelic acid, alpha-methyl-","Saeure","Saeuren"],"pathways":[],"growth_conditions":[],"references":[{"pubmed_id":19889834,"citation":"Boer, V. M., Crutchfield, C. A., Bradley, P. H., Botstein, D., Rabinowitz, J. D. (2010). \"Growth-limiting intracellular metabolites in yeast growing under diverse nutrient limitations.\" Mol Biol Cell 21:198-211."}],"proteins":[]}