{"ymdb_id":"YMDB01564","created_at":"2011-08-11T21:20:02.000Z","updated_at":"2016-10-18T17:12:05.000Z","name":"Ethylene glycol","cas":"107-21-1","state":"Liquid","melting_point":"-13 oC","description":"Ethylene glycol is an organic compound widely used as an automotive antifreeze and a precursor to polymers. Ethylene glycol is a substrate of yeast alcohol dehydrogenase [EC 1.1.1.1] which convert it to the corresponding aldehyde. Ethylene glycol is toxic, and ingestion can result in death. [PMID: 10092940]","experimental_water_solubility":"1000 mg/mL [RIDDICK,JA et al. (1986)]","experimental_logp_hydrophobicity":"-1.36 [HANSCH,C ET AL. (1995)]","location":null,"synthesis_reference":null,"chebi_id":"30742","hmdb_id":null,"kegg_id":"C01380","pubchem_id":"174","cs_id":"13835235","foodb_id":null,"wikipedia_link":null,"biocyc_id":null,"iupac":null,"traditional_iupac":null,"logp":null,"pka":null,"alogps_solubility":"9.50e+02 g/l","alogps_logp":"-1.53","alogps_logs":"1.18","acceptor_count":null,"donor_count":null,"rotatable_bond_count":null,"polar_surface_area":null,"refractivity":null,"polarizability":null,"formal_charge":"0","physiological_charge":null,"pka_strongest_basic":null,"pka_strongest_acidic":null,"bioavailability":null,"number_of_rings":null,"rule_of_five":"0","ghose_filter":"0","veber_rule":null,"mddr_like_rule":null,"synonyms":["1,2 Ethanediol","1,2-Dihydroxyethane","1,2-Ethanediol","2 Hydroxyethanol","2-Hydroxyethanol","Ethanediol","Glycol","Glycol, ethylene","Glycol, monoethylene","HO-CH2-CH2-OH","Monoethylene glycol"],"pathways":[],"growth_conditions":[{"growth_media":"YEB media with 0.5 mM glucose","concentration":"1050.0","concentration_units":"\u0026#181;M","error":"53.0"}],"references":[{"pubmed_id":17439666,"citation":"Castrillo, J. I., Zeef, L. A., Hoyle, D. C., Zhang, N., Hayes, A., Gardner, D. C., Cornell, M. J., Petty, J., Hakes, L., Wardleworth, L., Rash, B., Brown, M., Dunn, W. B., Broadhurst, D., O'Donoghue, K., Hester, S. S., Dunkley, T. P., Hart, S. R., Swainston, N., Li, P., Gaskell, S. J., Paton, N. W., Lilley, K. S., Kell, D. B., Oliver, S. G. (2007). \"Growth control of the eukaryote cell: a systems biology study in yeast.\" J Biol 6:4."}],"proteins":[]}