{"ymdb_id":"YMDB01213","created_at":"2011-07-24T19:12:54.000Z","updated_at":"2016-10-17T22:34:51.000Z","name":"PG(18:0/18:1(9Z))","cas":"66322-31-4","state":"Solid","melting_point":null,"description":"PG(18:0/18:1(9Z)) is a phosphatidylglycerol. Phosphatidylglycerols consist of a glycerol 3-phosphate backbone esterified to either saturated or unsaturated fatty acids on carbons 1 and 2. As is the case with diacylglycerols, phosphatidylglycerols can have many different combinations of fatty acids of varying lengths and saturation attached to the C-1 and C-2 positions. PG(18:0/18:1(9Z)), in particular, consists of one octadecanoyl chain  to the C-1 atom, and one 9Z-octadecenoyl  to the C-2 atom. In E. coli glycerophospholipid metabolism, phosphatidylglycerol is formed from phosphatidic acid (1,2-diacyl-sn-glycerol 3-phosphate) by a sequence of enzymatic reactions that proceeds via two intermediates, cytidine diphosphate diacylglycerol (CDP-diacylglycerol) and phosphatidylglycerophosphate (PGP, a phosphorylated phosphatidylglycerol). Phosphatidylglycerols, along with CDP-diacylglycerol, also serve as precursor molecules for the synthesis of cardiolipin, a phospholipid found in membranes.","experimental_water_solubility":null,"experimental_logp_hydrophobicity":null,"location":null,"synthesis_reference":null,"chebi_id":null,"hmdb_id":"HMDB10604","kegg_id":null,"pubchem_id":"119120","cs_id":"24768103","foodb_id":null,"wikipedia_link":null,"biocyc_id":null,"iupac":"[(2S)-2,3-dihydroxypropoxy][(2R)-2-[(9Z)-octadec-9-enoyloxy]-3-(octadecanoyloxy)propoxy]phosphinic acid","traditional_iupac":"(2S)-2,3-dihydroxypropoxy((2R)-2-[(9Z)-octadec-9-enoyloxy]-3-(octadecanoyloxy)propoxy)phosphinic acid","logp":"12.353404522666665","pka":"13.641245576372423","alogps_solubility":"8.46e-05 g/l","alogps_logp":"8.58","alogps_logs":"-6.96","acceptor_count":"6","donor_count":"3","rotatable_bond_count":"43","polar_surface_area":"148.82000000000002","refractivity":"214.82950000000005","polarizability":"94.61617236886448","formal_charge":"0","physiological_charge":"-1","pka_strongest_basic":"-2.9689647678483633","pka_strongest_acidic":"1.8907737771908404","bioavailability":"0","number_of_rings":"0","rule_of_five":"0","ghose_filter":"0","veber_rule":"0","mddr_like_rule":"0","synonyms":["1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-glycerol)","1-stearoyl-2-oleoyl-sn-glycero-3-phosphoglycerol","GPG(18:0/18:1)","GPG(18:0/18:1n9)","GPG(18:0/18:1w9)","GPG(36:1)","PG(18:0/18:1)","PG(18:0/18:1n9)","PG(18:0/18:1w9)","PG(36:1)","Phosphatidylglycerol(18:0/18:1)","Phosphatidylglycerol(18:0/18:1n9)","Phosphatidylglycerol(18:0/18:1w9)","Phosphatidylglycerol(36:1)"],"pathways":[],"growth_conditions":[],"references":[{"pubmed_id":19174513,"citation":"Ejsing, C. S., Sampaio, J. L., Surendranath, V., Duchoslav, E., Ekroos, K., Klemm, R. W., Simons, K., Shevchenko, A. (2009). \"Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry.\" Proc Natl Acad Sci U S A 106:2136-2141."}],"proteins":[]}