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| Identification |
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| YMDB ID | YMDB01064 |
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| Name | (S)-malate(2-) |
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| Species | Saccharomyces cerevisiae |
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| Strain | Brewer's yeast |
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| Description | (S)-malate(2-), also known as L-malate or (S)-malic acid, belongs to the class of organic compounds known as beta hydroxy acids and derivatives. Beta hydroxy acids and derivatives are compounds containing a carboxylic acid substituted with a hydroxyl group on the C3 carbon atom (S)-malate(2-) is an extremely weak basic (essentially neutral) compound (based on its pKa) (S)-malate(2-) may be a unique S. cerevisiae (yeast) metabolite. |
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| Structure | |
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| Synonyms | - (S)-Malate
- (S)-Malic acid
- (S)-Malic acid(2-)
- L-Malate
- L-Malic acid
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| CAS number | Not Available |
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| Weight | Average: 132.0716
Monoisotopic: 132.005873238 |
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| InChI Key | BJEPYKJPYRNKOW-REOHCLBHSA-L |
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| InChI | InChI=1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/p-2/t2-/m0/s1 |
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| IUPAC Name | (2S)-2-hydroxybutanedioate |
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| Traditional IUPAC Name | L-malate |
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| Chemical Formula | C4H4O5 |
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| SMILES | O[C@@H](CC([O-])=O)C([O-])=O |
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| Chemical Taxonomy |
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| Description | belongs to the class of organic compounds known as beta hydroxy acids and derivatives. Beta hydroxy acids and derivatives are compounds containing a carboxylic acid substituted with a hydroxyl group on the C3 carbon atom. |
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| Kingdom | Organic compounds |
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| Super Class | Organic acids and derivatives |
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| Class | Hydroxy acids and derivatives |
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| Sub Class | Beta hydroxy acids and derivatives |
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| Direct Parent | Beta hydroxy acids and derivatives |
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| Alternative Parents | |
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| Substituents | - Short-chain hydroxy acid
- Beta-hydroxy acid
- Fatty acid
- Dicarboxylic acid or derivatives
- Secondary alcohol
- Carboxylic acid
- Carboxylic acid derivative
- Organic oxygen compound
- Organic oxide
- Hydrocarbon derivative
- Organooxygen compound
- Carbonyl group
- Alcohol
- Organic anion
- Aliphatic acyclic compound
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| Molecular Framework | Aliphatic acyclic compounds |
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| External Descriptors | |
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| Physical Properties |
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| State | Not Available |
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| Charge | -2 |
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| Melting point | Not Available |
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| Experimental Properties | | Property | Value | Reference |
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| Water Solubility | Not Available | PhysProp | | LogP | Not Available | PhysProp |
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| Predicted Properties | |
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| Biological Properties |
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| Cellular Locations | - extracellular
- mitochondrion
- peroxisome
- cytoplasm
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| Organoleptic Properties | Not Available |
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| SMPDB Pathways |
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| KEGG Pathways | |
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| SMPDB Reactions | Not Available |
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| KEGG Reactions | |
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| Concentrations |
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| Intracellular Concentrations | Not Available |
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| Extracellular Concentrations | Not Available |
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| Spectra |
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| Spectra | |
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| References |
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| References: | - Kunze, M., Kragler, F., Binder, M., Hartig, A., Gurvitz, A. (2002). "Targeting of malate synthase 1 to the peroxisomes of Saccharomyces cerevisiae cells depends on growth on oleic acid medium." Eur J Biochem 269:915-922.11846793
- Przybyla-Zawislak, B., Gadde, D. M., Ducharme, K., McCammon, M. T. (1999). "Genetic and biochemical interactions involving tricarboxylic acid cycle (TCA) function using a collection of mutants defective in all TCA cycle genes." Genetics 152:153-166.10224250
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| Synthesis Reference: | Not Available |
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| External Links: | | Resource | Link |
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| CHEBI ID | 15589 | | HMDB ID | Not Available | | Pubchem Compound ID | 5459792 | | Kegg ID | Not Available | | ChemSpider ID | Not Available | | FOODB ID | Not Available | | Wikipedia ID | Not Available | | BioCyc ID | MAL |
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