{"ymdb_id":"YMDB01061","created_at":"2011-07-21T17:05:44.000Z","updated_at":"2016-09-08T18:36:13.000Z","name":"3-Phosphonatooxypyruvate(3-)","cas":null,"state":null,"melting_point":null,"description":"3-Phosphonatooxypyruvate is an intermediate in serine biosynthesis pathway. Serine is an important precursor used for the biosynthesis of glycine, cysteine, tryptophan, and phospholipids. [Biocyc SERSYN-PWY]","experimental_water_solubility":null,"experimental_logp_hydrophobicity":null,"location":"cytoplasm","synthesis_reference":null,"chebi_id":"18110","hmdb_id":null,"kegg_id":null,"pubchem_id":null,"cs_id":"4573923","foodb_id":null,"wikipedia_link":null,"biocyc_id":null,"iupac":"2-oxo-3-(phosphonatooxy)propanoate","traditional_iupac":"3-phosphonooxypyruvate","logp":"-0.8749401239999998","pka":"2.771821818294329","alogps_solubility":"3.41e+01 g/l","alogps_logp":"-0.46","alogps_logs":"-0.84","acceptor_count":"6","donor_count":"0","rotatable_bond_count":"4","polar_surface_area":"129.62","refractivity":"39.15850000000001","polarizability":"11.707053784981882","formal_charge":"-3","physiological_charge":"-3","pka_strongest_basic":null,"pka_strongest_acidic":"1.0202501691523165","bioavailability":"1","number_of_rings":"0","rule_of_five":"1","ghose_filter":"0","veber_rule":"0","mddr_like_rule":"0","synonyms":["3-phospho-Hydroxypyruvic acid","3-Phosphohydroxypyruvate","3-Phosphohydroxypyruvic acid","3-Phosphonooxypyruvate","3-Phosphonooxypyruvic acid","Phosphohydroxypyruvate","Phosphohydroxypyruvic acid"],"pathways":[{"name":"glycine metabolism","kegg_map_id":null},{"name":"serine metabolism","kegg_map_id":null}],"growth_conditions":[],"references":[{"pubmed_id":8017107,"citation":"Belhumeur, P., Fortin, N., Clark, M. W. (1994). \"A gene from Saccharomyces cerevisiae which codes for a protein with significant homology to the bacterial 3-phosphoserine aminotransferase.\" Yeast 10:385-389."},{"pubmed_id":12525494,"citation":"Albers, E., Laize, V., Blomberg, A., Hohmann, S., Gustafsson, L. (2003). \"Ser3p (Yer081wp) and Ser33p (Yil074cp) are phosphoglycerate dehydrogenases in Saccharomyces cerevisiae.\" J Biol Chem 278:10264-10272."}],"proteins":[]}