{"ymdb_id":"YMDB01042","created_at":"2011-07-21T17:00:32.000Z","updated_at":"2016-09-08T18:36:11.000Z","name":"Ureidoglycolic acid","cas":null,"state":null,"melting_point":null,"description":"(S)-Ureidoglycolic acid is an hydrolysis product of allantoate in the allantoin degradation to glyoxylate pathway. Allantoin is a common product of purine degradation. Allantoin is rich in nitrogen and many organisms are able to degrade it and recycle it. Yeast can use allantoin as sole nitrogen source by degrading it to urea, CO2 and glyoxylate. Urea is further degraded to ammonia. [Biocyc PWY-5694]","experimental_water_solubility":null,"experimental_logp_hydrophobicity":null,"location":"cytoplasm","synthesis_reference":null,"chebi_id":"49050","hmdb_id":null,"kegg_id":"C05241","pubchem_id":"16219415","cs_id":"329","foodb_id":null,"wikipedia_link":null,"biocyc_id":"CPD-1091","iupac":"2-hydroxy-2-[(C-hydroxycarbonimidoyl)amino]acetic acid","traditional_iupac":"hydroxy(C-hydroxycarbonimidoylamino)acetic acid","logp":"-2.5938180631809367","pka":"8.683690123308399","alogps_solubility":"5.48e+00 g/l","alogps_logp":"-1.82","alogps_logs":"-1.39","acceptor_count":"6","donor_count":"5","rotatable_bond_count":"2","polar_surface_area":"113.64000000000001","refractivity":"36.258900000000004","polarizability":"10.806090477403519","formal_charge":"0","physiological_charge":"-1","pka_strongest_basic":"5.340051936950143","pka_strongest_acidic":"1.778100826000688","bioavailability":"1","number_of_rings":"0","rule_of_five":"1","ghose_filter":"0","veber_rule":"0","mddr_like_rule":"0","synonyms":["Ureidoglycolate"],"pathways":[],"growth_conditions":[],"references":[{"pubmed_id":4604238,"citation":"Lawther, R. P., Riemer, E., Chojnacki, B., Cooper, T. G. (1974). \"Clustering of the genes for allantoin degradation in Saccharomyces cerevisiae.\" J Bacteriol 119:461-468."},{"pubmed_id":1776360,"citation":"Yoo, H. S., Cooper, T. G. (1991). \"The ureidoglycollate hydrolase (DAL3) gene in Saccharomyces cerevisiae.\" Yeast 7:693-698."}],"proteins":[]}