{"ymdb_id":"YMDB00994","created_at":"2011-06-14T19:33:53.000Z","updated_at":"2016-09-08T18:36:08.000Z","name":"glycerol 2-phosphate","cas":"17181-54-3","state":"Solid","melting_point":null,"description":"Glycerol 2-phosphate is an intermediate in the CDP-2-glycerol biosynthesis pathway, a capsular polysaccharide found in pathogen bacteria. [Biocyc PWY-6626]","experimental_water_solubility":null,"experimental_logp_hydrophobicity":null,"location":null,"synthesis_reference":null,"chebi_id":"17270","hmdb_id":"HMDB02520","kegg_id":"C02979","pubchem_id":"2526","cs_id":"2431","foodb_id":null,"wikipedia_link":null,"biocyc_id":"CPD-536","iupac":"[(1,3-dihydroxypropan-2-yl)oxy]phosphonic acid","traditional_iupac":"β-glycerophosphorate","logp":"-1.9625800539999998","pka":"6.165546869512347","alogps_solubility":"3.07e+01 g/l","alogps_logp":"-1.84","alogps_logs":"-0.75","acceptor_count":"5","donor_count":"4","rotatable_bond_count":"4","polar_surface_area":"107.22","refractivity":"31.389","polarizability":"13.288127184427333","formal_charge":"0","physiological_charge":"-2","pka_strongest_basic":"-2.9891179827681142","pka_strongest_acidic":"1.134625237612609","bioavailability":"1","number_of_rings":"0","rule_of_five":"1","ghose_filter":"0","veber_rule":"0","mddr_like_rule":"0","synonyms":["1,2,3-Propanetriol, 2-(dihydrogen phosphate)","1,3-Hydroxy-2-propyl dihydrogen phosphate","2-HYDROXY-1-(HYDROXYMETHYL)ETHYL DIHYDROGEN PHOSPHATE","819-83-0 (di-hydrochloride salt)","beta-Glycerophosphorate","beta-Glycerophosphoric acid","Glycerol 2-phosphate","Glycerol-2-phosphate","Glycerol-2-phosphic acid"],"pathways":[],"growth_conditions":[],"references":[{"pubmed_id":21062828,"citation":"Scheer, M., Grote, A., Chang, A., Schomburg, I., Munaretto, C., Rother, M., Sohngen, C., Stelzer, M., Thiele, J., Schomburg, D. (2011). \"BRENDA, the enzyme information system in 2011.\" Nucleic Acids Res 39:D670-D676."}],"proteins":[{"created_at":"2011-05-24T20:34:21.000Z","updated_at":"2011-05-29T14:01:21.000Z","name":"Enolase-phosphatase E1","uniprot_id":"P32626","uniprot_name":"ENOPH_YEAST","enzyme":true,"transporter":false,"gene_name":"UTR4","num_residues":227,"molecular_weight":"25187.19922","theoretical_pi":"5.3","general_function":"Involved in catalytic activity","specific_function":"Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene)","reactions":[{"id":2327,"direction":"\u003e","locations":"Cytoplasm. Nucleus","altext":"5-(methylthio)-2,3-dioxopentyl phosphate + H(2)O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate.","export":false,"pw_reaction_id":null,"source":null},{"id":2328,"direction":"\u003e","locations":"Cytoplasmic;Cytoplasm. Nucleus","altext":"2-Phosphoglycolate + H2O = glycolate + phosphate","export":false,"pw_reaction_id":null,"source":null},{"id":3792,"direction":null,"locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006311","source":"Smpdb"}],"signal_regions":"None","transmembrane_regions":"None","pdb_id":null,"cellular_location":"Cytoplasm. Nucleus","genbank_gene_id":"U18779","genbank_protein_id":"603641","gene_card_id":"UTR4","chromosome_location":"chromosome 5","locus":"YEL038W","synonyms":["2,3-diketo-5-methylthio-1-phosphopentane phosphatase","Unknown transcript 4 protein"],"enzyme_classes":["3.1.3.77","3.1.3.18"],"go_classes":[{"category":"Component","description":" Not Available"},{"category":"Function","description":" phosphatase activity"},{"category":"Function","description":" phosphoglycolate phosphatase activity"},{"category":"Function","description":" acireductone synthase activity"},{"category":"Function","description":" catalytic activity"},{"category":"Function","description":" binding"},{"category":"Function","description":" ion binding"},{"category":"Function","description":" cation binding"},{"category":"Function","description":" metal ion binding"},{"category":"Function","description":" hydrolase activity"},{"category":"Function","description":" hydrolase activity, acting on ester bonds"},{"category":"Function","description":" phosphoric ester hydrolase activity"},{"category":"Process","description":" cellular amino acid biosynthetic process"},{"category":"Process","description":" metabolic process"},{"category":"Process","description":" amino acid salvage"},{"category":"Process","description":" L-methionine salvage from methylthioadenosine"},{"category":"Process","description":" cellular metabolic process"},{"category":"Process","description":" cellular amino acid and derivative metabolic process"},{"category":"Process","description":" cellular amino acid metabolic process"}],"pfams":[{"name":"Hydrolase","identifier":"PF00702"}],"pathways":[{"name":"Cysteine and methionine metabolism","kegg_map_id":"00270"},{"name":"Methionine metabolism and salvage","kegg_map_id":null}],"gene_sequence":"ATGGTCATTGGGCAAAAGGTCCTGCTAGCTCGTATACCAAAAATGGGAGACAATTACTCGACTTACTTGCTTGATATTGAAGGGACAGTGTGCCCGATCTCGTTCGTGAAGGAGACTTTATTCCCTTATTTCACGAATAAAGTGCCGCAATTGGTTCAACAGGATACAAGGGACTCCCCGGTTTCCAACATTCTGTCGCAGTTTCACATCGACAATAAGGAGCAGTTGCAGGCGCATATTTTGGAGTTGGTGGCCAAGGATGTGAAGGATCCAATCTTGAAACAGTTGCAAGGCTACGTCTGGGCTCACGGATACGAATCTGGGCAGATTAAGGCGCCCGTTTATGCAGATGCTATTGACTTTATCAAGAGGAAGAAGCGTGTGTTTATCTACTCTAGTGGATCTGTAAAGGCACAGAAATTGCTGTTCGGGTATGTTCAGGATCCCAACGCGCCTGCGCATGATTCGTTGGATTTGAATTCTTATATAGATGGTTATTTCGACATCAACACTTCTGGAAAGAAAACCGAAACACAGTCTTACGCCAACATCTTGCGGGATATCGGTGCGAAGGCTAGCGAGGTACTGTTCTTGAGCGATAATCCATTGGAATTGGACGCAGCGGCCGGCGTTGGAATAGCTACTGGGTTAGCTTCCCGACCTGGTAATGCACCTGTCCCCGATGGGCAAAAGTACCAGGTATACAAGAATTTTGAAACTCTTTAA","protein_sequence":"MGDNYSTYLLDIEGTVCPISFVKETLFPYFTNKVPQLVQQDTRDSPVSNILSQFHIDNKEQLQAHILELVAKDVKDPILKQLQGYVWAHGYESGQIKAPVYADAIDFIKRKKRVFIYSSGSVKAQKLLFGYVQDPNAPAHDSLDLNSYIDGYFDINTSGKKTETQSYANILRDIGAKASEVLFLSDNPLELDAAAGVGIATGLASRPGNAPVPDGQKYQVYKNFETL"},{"created_at":"2011-05-27T18:43:37.000Z","updated_at":"2011-05-29T14:01:21.000Z","name":"Putative uncharacterized hydrolase YOR131C","uniprot_id":"Q12486","uniprot_name":"YOR31_YEAST","enzyme":true,"transporter":false,"gene_name":null,"num_residues":218,"molecular_weight":"24839.80078","theoretical_pi":"6.63","general_function":"Involved in catalytic activity","specific_function":null,"reactions":[{"id":2328,"direction":"\u003e","locations":"Cytoplasmic;Cytoplasm. Nucleus","altext":"2-Phosphoglycolate + H2O = glycolate + phosphate","export":false,"pw_reaction_id":null,"source":null}],"signal_regions":"None","transmembrane_regions":"None","pdb_id":null,"cellular_location":"Cytoplasm. Nucleus","genbank_gene_id":"X90518","genbank_protein_id":"1050822","gene_card_id":null,"chromosome_location":null,"locus":"YOR131C","synonyms":[],"enzyme_classes":["3.-.-.-","3.1.3.18"],"go_classes":[{"category":"Component","description":" Not Available"},{"category":"Function","description":" catalytic activity"},{"category":"Function","description":" hydrolase activity"},{"category":"Function","description":" hydrolase activity, acting on ester bonds"},{"category":"Function","description":" phosphoric ester hydrolase activity"},{"category":"Function","description":" phosphatase activity"},{"category":"Function","description":" phosphoglycolate phosphatase activity"},{"category":"Process","description":" metabolic process"}],"pfams":[{"name":"Hydrolase","identifier":"PF00702"}],"pathways":[],"gene_sequence":"ATGACAAAGCTACAAGGACTACAGGGATTAAAACACATCAAAGCGGTTGTATTTGATATGGATGGCACATTATGCCTACCCCAGCCTTGGATGTTTCCAGCAATGAGAAACGCCATAGGATTGGAGGACAAATCGATTGATATCCTTCATTTCATTGATACATTGCCCACAGAAAAAGAAAAAAAAGAAGCGCATGATAGAATAGAATTAGTTGAGGCAAAAGCCATGAAGGAGATGCAACCGCAGCCTGGTCTGGTTGACATAATGAGGTATTTGACGAAAAATGGTATTAGCAAGAACATATGTACTAGAAATGTCGGAGCCCCGGTAGAGACTTTTGTTAAAAGATTTATTCCATCCGAGCTTTCGAGGTTTGACTATATTGTGACAAGGGAGTTTAGGCCTACAAAACCGCAACCAGACCCATTATTACACATCGCCTCGAAGCTAAATATAAGGCCCTTGGAAATGATCATGGTAGGAGATTCATTTGACGACATGAAATCCGGTAGATCTGCTGGATGTTTCACGGTATTACTCAAGAATCATGTGAATGGACATTTACTGCTCGAACATAAAGAACTAGTAGACGTTTCAGTAGAGGATCTTTCCGAAATAATTGAATTGATTCAAAATATGAATAAAGAAAGTTTCTAA","protein_sequence":"MTKLQGLQGLKHIKAVVFDMDGTLCLPQPWMFPAMRNAIGLEDKSIDILHFIDTLPTEKEKKEAHDRIELVEAKAMKEMQPQPGLVDIMRYLTKNGISKNICTRNVGAPVETFVKRFIPSELSRFDYIVTREFRPTKPQPDPLLHIASKLNIRPLEMIMVGDSFDDMKSGRSAGCFTVLLKNHVNGHLLLEHKELVDVSVEDLSEIIELIQNMNKESF"},{"created_at":"2011-05-27T18:44:06.000Z","updated_at":"2011-05-29T14:08:02.000Z","name":"Uncharacterized protein YMR130W","uniprot_id":"Q04223","uniprot_name":"YM14_YEAST","enzyme":true,"transporter":false,"gene_name":null,"num_residues":302,"molecular_weight":"35278.10156","theoretical_pi":"6.18","general_function":"Involved in catalytic activity","specific_function":null,"reactions":[{"id":2328,"direction":"\u003e","locations":"Cytoplasmic;Cytoplasm. Nucleus","altext":"2-Phosphoglycolate + H2O = glycolate + phosphate","export":false,"pw_reaction_id":null,"source":null}],"signal_regions":"None","transmembrane_regions":"None","pdb_id":null,"cellular_location":"Cytoplasmic","genbank_gene_id":"AY557987","genbank_protein_id":"45269864","gene_card_id":null,"chromosome_location":null,"locus":"YMR130W","synonyms":[],"enzyme_classes":["3.1.3.18"],"go_classes":[{"category":"Component","description":" Not Available"},{"category":"Function","description":" catalytic activity"},{"category":"Function","description":" hydrolase activity"},{"category":"Function","description":" hydrolase activity, acting on ester bonds"},{"category":"Function","description":" phosphoric ester hydrolase activity"},{"category":"Function","description":" phosphatase activity"},{"category":"Function","description":" phosphoglycolate phosphatase activity"},{"category":"Process","description":" metabolic process"}],"pfams":[{"name":"Hydrolase","identifier":"PF00702"}],"pathways":[],"gene_sequence":"ATGACCTATCCGAAAAGAATACCTATAAATGCGTGGTCTGAAGTTCATAGGGTGGCAAGGCCACTAATTATTACTTTCGACGCATATAATACACTATACGCCACAAAACTTCCCGTCATGGAACAATACTGCATTGTTGGGCGTAAATATGGTATCAAGGCGAATCCTTCGACTTTAACAAACAATTTTCCACACGTTTTTAAAAAACTGAAGGAAGACTATCCCCAATACGGAAAATATTCTGGTATCAAGCCCGAACAATGGTGGTCCATCTTGATTAGGAACGTCTTCGCACCAAACGAAATTCCCGATGAGATGATAAATGAAATATTAATGCGGTTTGAGGGCTTCGATTCGTATTTTGTTTATCCAGATTTGATCAAATTTTTAAAGGATTTGAAGTCAAGACATCCTGATGTTATCTTAGGAATAGTAAGCAATACTGATCCAATTTTTTACAAATTATTAAAGAATATCGGATTATTTGAGACATTTTCCGGTCACATTTATTTATCATATGAGCTTAATCTCGCCAAACCTGATAGAGCAATATTTCAATATGCGCTTGACGATATTATATCTAAACAACCTCATTTACTCGAAAAGTACACCAGGGAGGAAATTCTACAGCATTGCTTTCACATCGGAGATGAATTAAAGAACGATCTCGAAGGGGCAGAAGCTGCCGGTTGGACTGGTATACTGTTAGATAGAAATGATAAATACGGGTTTCTTTCAAACTCGATTAGTAAACCAATGCGGGACGAATACAAGCTGTCAATTGATAAAATAGATAATAATTCAATAAACACTTGGGAAGCCAATACTAAGCAAACTGACACGTTACAGTTGAGTGAAAGAAAGTACGTTGTTTCGAATCTTGAGGTTTTAGAGGAACTCTTTCCCTGA","protein_sequence":"MTYPKRIPINAWSEVHRVARPLIITFDAYNTLYATKLPVMEQYCIVGRKYGIKANPSTLTNNFPHVFKKLKEDYPQYGKYSGIKPEQWWSILIRNVFAPNEIPDEMINEILMRFEGFDSYFVYPDLIKFLKDLKSRHPDVILGIVSNTDPIFYKLLKNIGLFETFSGHIYLSYELNLAKPDRAIFQYALDDIISKQPHLLEKYTREEILQHCFHIGDELKNDLEGAEAAGWTGILLDRNDKYGFLSNSISKPMRDEYKLSIDKIDNNSINTWEANTKQTDTLQLSERKYVVSNLEVLEELFP"}]}