Glucose 6-phosphate (YMDB00947)

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Identification

YMDB ID

YMDB00947

Name

Glucose 6-phosphate

Species

Saccharomyces cerevisiae

Strain

Baker's yeast

Description

Glucose 6-phosphate, also known as robison ester or GLC6P, belongs to the class of organic compounds known as hexose phosphates. These are carbohydrate derivatives containing a hexose substituted by one or more phosphate groups. Glucose 6-phosphate is an extremely weak basic (essentially neutral) compound (based on its pKa). Glucose 6-phosphate exists in all living species, ranging from bacteria to humans.

Structure

MOL SDF PDB SMILES InChI

Synonyms

a-D-glucose 6- phosphate
alpha-D-glucose 6- phosphate
alpha-D-glucose 6-phosphate
alpha-D-Hexose 6-phosphate
D-Glucose 6-phosphate
D-Glucose-6-dihydrogen phosphate
D-Hexose 6-phosphate
D(+)-Glucopyranose 6-phosphate
Glucose 6-phosphate
Glucose 6-phosphic acid
Glucose-6-phosphate
Robison ester
6-O-Phosphono-D-glucopyranose
GLC6p
D-Glucose 6-phosphoric acid
Glucose 6-phosphoric acid
D-Glucopyranose 6-phosphoric acid

CAS number

56-73-5

Weight

Average: 260.1358
Monoisotopic: 260.029718526

InChI Key

NBSCHQHZLSJFNQ-GASJEMHNSA-N

InChI

InChI=1S/C6H13O9P/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8/h2-10H,1H2,(H2,11,12,13)/t2-,3-,4+,5-,6?/m1/s1

IUPAC Name

{[(2R,3S,4S,5R)-3,4,5,6-tetrahydroxyoxan-2-yl]methoxy}phosphonic acid

Traditional IUPAC Name

glucose 6-phosphate

Chemical Formula

C₆H₁₃O₉P

SMILES

[H]OC1([H])O[C@]([H])(C([H])([H])OP(=O)(O[H])O[H])[C@@]([H])(O[H])[C@]([H])(O[H])[C@@]1([H])O[H]

Chemical Taxonomy

Description

belongs to the class of organic compounds known as hexose phosphates. These are carbohydrate derivatives containing a hexose substituted by one or more phosphate groups.

Kingdom

Organic compounds

Super Class

Organic oxygen compounds

Class

Organooxygen compounds

Sub Class

Carbohydrates and carbohydrate conjugates

Direct Parent

Hexose phosphates

Alternative Parents

Substituents

Hexose phosphate
Monosaccharide phosphate
Monoalkyl phosphate
Organic phosphoric acid derivative
Alkyl phosphate
Oxane
Phosphoric acid ester
Hemiacetal
Secondary alcohol
Oxacycle
Organoheterocyclic compound
Polyol
Hydrocarbon derivative
Alcohol
Organic oxide
Aliphatic heteromonocyclic compound

Molecular Framework

Aliphatic heteromonocyclic compounds

External Descriptors

D-hexopyranose 6-phosphate (CHEBI:4170 )
D-glucose 6-phosphate (CHEBI:4170 )

Physical Properties

State

Liquid

Charge

Melting point

Not Available

Experimental Properties

Property	Value	Reference
Water Solubility	Not Available	PhysProp
LogP	Not Available	PhysProp

Predicted Properties

Property	Value	Source
Water Solubility	31.4 g/L	ALOGPS
logP	-2.1	ALOGPS
logP	-3.1	ChemAxon
logS	-0.92	ALOGPS
pKa (Strongest Acidic)	1.22	ChemAxon
pKa (Strongest Basic)	-3.6	ChemAxon
Physiological Charge	-2	ChemAxon
Hydrogen Acceptor Count	8	ChemAxon
Hydrogen Donor Count	6	ChemAxon
Polar Surface Area	156.91 Å²	ChemAxon
Rotatable Bond Count	3	ChemAxon
Refractivity	46.8 m³·mol⁻¹	ChemAxon
Polarizability	21 Å³	ChemAxon
Number of Rings	1	ChemAxon
Bioavailability	1	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	Yes	ChemAxon
MDDR-like Rule	Yes	ChemAxon

Biological Properties

Cellular Locations

Not Available

Organoleptic Properties

Not Available

SMPDB Pathways

Amino sugar and nucleotide sugar metabolism	PW002413
Ethanol fermentation	PW002448
Fructose Metabolism	PW002390
Glycolysis I	PW002386
Inositol phosphate metabolism	PW002495

KEGG Pathways

Amino sugar and nucleotide sugar metabolism	ec00520
Galactose metabolism	ec00052
Glycolysis / Gluconeogenesis	ec00010
Inositol phosphate metabolism	ec00562
Pentose phosphate pathway	ec00030

SMPDB Reactions

D-Glucose + Adenosine triphosphate → Glucose 6-phosphate + ADP

Alpha-D-Glucose + Adenosine triphosphate → Glucose 6-phosphate + ADP

Alpha-D-Glucose + Adenosine triphosphate → ADP + hydron + Glucose 6-phosphate

Fructose 6-phosphate ↔ Glucose 6-phosphate

Glucose 6-phosphate → β-D-fructofuranose 6-phosphate

KEGG Reactions

Not Available

Concentrations

Intracellular Concentrations

Intracellular Concentration	Substrate	Growth Conditions	Strain	Citation
2050 ± 110 µM	20 ml 2% (wt/vol) glucose, 0.5% (wt/vol) ammonium sulfate, 0.17% (wt/vol) yeast nitrogen base without amino acids (Difco, Detroit, MI) and 100 mM potassium phthalate at pH 5.0, supplemented with required nutrients (40 mg/L uracil, 40 mg/L Ltryptophan, 60	aerobic	Baker's yeast	PMID: 11135551
2300 ± 200 µM	Synthetic medium with 2% glucose	aerobic;growing cells	Baker's yeast	PMID: 6229402
560 ± 80 µM	Synthetic medium with 2% glucose	aerobic;resting cells	Baker's yeast	PMID: 6229402
340 ± 130 µM	Synthetic medium with 2% glucose	anaerobic;resting cells	Baker's yeast	PMID: 6229402
1360 ± 600 µM	Synthetic medium with 2% galactose	aerobic;resting cells	Baker's yeast	PMID: 6229402
Conversion Details Here

Extracellular Concentrations

Not Available

Spectra

Spectrum Type	Description	Splash Key	View
GC-MS	GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (6 TMS)	splash10-000b-1932000000-59f4881b86595037d013	JSpectraViewer \| MoNA
GC-MS	GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (6 TMS)	splash10-0f7t-1933000000-4894135f21c21c369428	JSpectraViewer \| MoNA
GC-MS	GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (6 TMS; 1 MEOX)	splash10-00di-9522000000-81266970683faa1f2aaf	JSpectraViewer \| MoNA
GC-MS	GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (6 TMS; 1 MEOX)	splash10-00di-9412000000-2f2a0e772025b48bf6f3	JSpectraViewer \| MoNA
GC-MS	GC-MS Spectrum - GC-MS (1 MEOX; 6 TMS)	splash10-000j-1956000000-692b4df2b9c16f6a780c	JSpectraViewer \| MoNA
GC-MS	GC-MS Spectrum - GC-MS (1 MEOX; 6 TMS)	splash10-000i-1957000000-bd94955ffc1474153a48	JSpectraViewer \| MoNA
GC-MS	GC-MS Spectrum - GC-MS (6 TMS)	splash10-0v0a-0596000000-676527ddfc1d596e78f8	JSpectraViewer \| MoNA
GC-MS	GC-MS Spectrum - GC-EI-TOF (Non-derivatized)	splash10-000b-1932000000-59f4881b86595037d013	JSpectraViewer \| MoNA
GC-MS	GC-MS Spectrum - GC-EI-TOF (Non-derivatized)	splash10-0f7t-1933000000-4894135f21c21c369428	JSpectraViewer \| MoNA
GC-MS	GC-MS Spectrum - GC-EI-TOF (Non-derivatized)	splash10-00di-9522000000-81266970683faa1f2aaf	JSpectraViewer \| MoNA
GC-MS	GC-MS Spectrum - GC-EI-TOF (Non-derivatized)	splash10-00di-9412000000-2f2a0e772025b48bf6f3	JSpectraViewer \| MoNA
GC-MS	GC-MS Spectrum - GC-MS (Non-derivatized)	splash10-000j-1956000000-692b4df2b9c16f6a780c	JSpectraViewer \| MoNA
GC-MS	GC-MS Spectrum - GC-MS (Non-derivatized)	splash10-000i-1957000000-bd94955ffc1474153a48	JSpectraViewer \| MoNA
GC-MS	GC-MS Spectrum - GC-MS (Non-derivatized)	splash10-0v0a-0596000000-676527ddfc1d596e78f8	JSpectraViewer \| MoNA
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	splash10-0005-9740000000-a6e81224fb97751dc2e6	JSpectraViewer
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (4 TMS) - 70eV, Positive	splash10-001i-6252790000-ef5662fb1886367e07f2	JSpectraViewer
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	Not Available	JSpectraViewer
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	Not Available	JSpectraViewer
LC-MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 10V, N/A (Annotated)	splash10-03di-0090000000-5653def80d1b5ff0eebb	JSpectraViewer \| MoNA
LC-MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 25V, N/A (Annotated)	splash10-000b-9200000000-66741d773ac31b347625	JSpectraViewer \| MoNA
LC-MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 40V, N/A (Annotated)	splash10-000t-9000000000-068809fcfaff0d387e6b	JSpectraViewer \| MoNA
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Negative	splash10-0a4i-1090000000-d6e539d78b38c01dafea	JSpectraViewer \| MoNA
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Negative	splash10-0002-9210000000-8b9ff1c5095f48a81fef	JSpectraViewer \| MoNA
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Negative	splash10-0002-9000000000-f6e1147852f75db4c0a4	JSpectraViewer \| MoNA
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Negative	splash10-002b-9000000000-1c52fd659f8a2b795e51	JSpectraViewer \| MoNA
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Negative	splash10-004i-9000000000-d3f6a05e18ea6d56c56d	JSpectraViewer \| MoNA
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Positive	splash10-0006-0890000000-5f3047c92c970dfe6927	JSpectraViewer \| MoNA
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Positive	splash10-004i-0900000000-b84eb7685667fa7ee85e	JSpectraViewer \| MoNA
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Positive	splash10-004i-2900000000-d4a0d51bb6e2da28533a	JSpectraViewer \| MoNA
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Positive	splash10-004i-6900000000-dfb5bcbd9a7439c32352	JSpectraViewer \| MoNA
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Positive	splash10-03gi-9600000000-a0922c82e185f6b5aa67	JSpectraViewer \| MoNA
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-IT (LC/MSD Trap XCT, Agilent Technologies) , Positive	splash10-0006-0290000000-7ac7b397c52f29cd3822	JSpectraViewer \| MoNA
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-IT (LC/MSD Trap XCT, Agilent Technologies) , Positive	splash10-052b-6590000000-5cdbc23378480ac55c4f	JSpectraViewer \| MoNA
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-IT (LC/MSD Trap XCT, Agilent Technologies) , Positive	splash10-004i-1900000000-b74270f21c6086362227	JSpectraViewer \| MoNA
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) , Negative	splash10-002b-9000000000-bc69e8fa215a3b82dcf2	JSpectraViewer \| MoNA
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ , negative	splash10-0a4i-0090000000-d6e539d78b38c01dafea	JSpectraViewer \| MoNA
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ , negative	splash10-0002-9210000000-10019f92fd1eca143bab	JSpectraViewer \| MoNA
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-03di-0490000000-94ea79ec673f4688b7a0	JSpectraViewer
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-03dm-5940000000-c649262446626dcb8d6e	JSpectraViewer
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-0uka-9800000000-aae2cb792906d2dec6cd	JSpectraViewer
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-0a6r-8290000000-8e20219f94b3fe964e38	JSpectraViewer
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-004i-9000000000-b19b64f5cb4124047baf	JSpectraViewer
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-004i-9000000000-ecb75a44e3d25affdf31	JSpectraViewer
1D NMR	13C NMR Spectrum	Not Available	JSpectraViewer
1D NMR	1H NMR Spectrum	Not Available	JSpectraViewer
1D NMR	1H NMR Spectrum	Not Available	JSpectraViewer
1D NMR	13C NMR Spectrum	Not Available	JSpectraViewer
1D NMR	1H NMR Spectrum	Not Available	JSpectraViewer
1D NMR	13C NMR Spectrum	Not Available	JSpectraViewer
1D NMR	1H NMR Spectrum	Not Available	JSpectraViewer
1D NMR	13C NMR Spectrum	Not Available	JSpectraViewer
1D NMR	1H NMR Spectrum	Not Available	JSpectraViewer
1D NMR	13C NMR Spectrum	Not Available	JSpectraViewer
1D NMR	1H NMR Spectrum	Not Available	JSpectraViewer
1D NMR	13C NMR Spectrum	Not Available	JSpectraViewer
1D NMR	1H NMR Spectrum	Not Available	JSpectraViewer
1D NMR	13C NMR Spectrum	Not Available	JSpectraViewer
1D NMR	1H NMR Spectrum	Not Available	JSpectraViewer
1D NMR	13C NMR Spectrum	Not Available	JSpectraViewer
1D NMR	1H NMR Spectrum	Not Available	JSpectraViewer
1D NMR	13C NMR Spectrum	Not Available	JSpectraViewer
1D NMR	1H NMR Spectrum	Not Available	JSpectraViewer
1D NMR	13C NMR Spectrum	Not Available	JSpectraViewer
1D NMR	1H NMR Spectrum	Not Available	JSpectraViewer
1D NMR	13C NMR Spectrum	Not Available	JSpectraViewer
2D NMR	[1H,1H] 2D NMR Spectrum	Not Available	JSpectraViewer
2D NMR	[1H,13C] 2D NMR Spectrum	Not Available	JSpectraViewer

References

References:

UniProt Consortium (2011). "Ongoing and future developments at the Universal Protein Resource." Nucleic Acids Res 39:D214-D219.21051339
Scheer, M., Grote, A., Chang, A., Schomburg, I., Munaretto, C., Rother, M., Sohngen, C., Stelzer, M., Thiele, J., Schomburg, D. (2011). "BRENDA, the enzyme information system in 2011." Nucleic Acids Res 39:D670-D676.21062828
Raamsdonk, L. M., Teusink, B., Broadhurst, D., Zhang, N., Hayes, A., Walsh, M. C., Berden, J. A., Brindle, K. M., Kell, D. B., Rowland, J. J., Westerhoff, H. V., van Dam, K., Oliver, S. G. (2001). "A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations." Nat Biotechnol 19:45-50.11135551
Coevoet, M. A., Hervagault, J. F. (1997). "Irreversible metabolic transitions: the glucose 6-phosphate metabolism in yeast cell-free extracts." Biochem Biophys Res Commun 234:162-166.9168982
Eschrich, K., Schellenberger, W., Hofmann, E. (1990). "A hysteretic cycle in glucose 6-phosphate metabolism observed in a cell-free yeast extract." Eur J Biochem 188:697-703.2158887
Thevelein, J. M., Hohmann, S. (1995). "Trehalose synthase: guard to the gate of glycolysis in yeast?" Trends Biochem Sci 20:3-10.7878741
Vaseghi, S., Baumeister, A., Rizzi, M., Reuss, M. (1999). "In vivo dynamics of the pentose phosphate pathway in Saccharomyces cerevisiae." Metab Eng 1:128-140.10935926
Senac, T., Hahn-Hagerdal, B. (1990). "Intermediary Metabolite Concentrations in Xylulose- and Glucose-Fermenting Saccharomyces cerevisiae Cells." Appl Environ Microbiol 56:120-126.16348083
Lagunas, R., Gancedo, C. (1983). "Role of phosphate in the regulation of the Pasteur effect in Saccharomyces cerevisiae." Eur J Biochem 137:479-483.6229402
Castrillo, J. I., Zeef, L. A., Hoyle, D. C., Zhang, N., Hayes, A., Gardner, D. C., Cornell, M. J., Petty, J., Hakes, L., Wardleworth, L., Rash, B., Brown, M., Dunn, W. B., Broadhurst, D., O'Donoghue, K., Hester, S. S., Dunkley, T. P., Hart, S. R., Swainston, N., Li, P., Gaskell, S. J., Paton, N. W., Lilley, K. S., Kell, D. B., Oliver, S. G. (2007). "Growth control of the eukaryote cell: a systems biology study in yeast." J Biol 6:4.17439666

Synthesis Reference:

Not Available

External Links:

Resource	Link
CHEBI ID	4170
HMDB ID	HMDB01401
Pubchem Compound ID	208
Kegg ID	C00668
ChemSpider ID	25057696
FOODB ID	FDB021818
Wikipedia	Glucose_6-phosphate
BioCyc ID	GLC-6-P

Enzymes

Protein Details

1. Phosphoglucomutase-2

General function:: Involved in intramolecular transferase activity, phosphotransferases
Specific function:: This enzyme participates in both the breakdown and synthesis of glucose. Can also act on mannose
Gene Name:: PGM2
Uniprot ID:: P37012
Molecular weight:: 63088.0

Reactions

Alpha-D-glucose 1-phosphate → alpha-D-glucose 6-phosphate.

Protein Details

2. Phosphoglucomutase-1

General function:: Involved in intramolecular transferase activity, phosphotransferases
Specific function:: This enzyme participates in both the breakdown and synthesis of glucose. Can also act on mannose
Gene Name:: PGM1
Uniprot ID:: P33401
Molecular weight:: 63111.30078

Reactions

Alpha-D-glucose 1-phosphate → alpha-D-glucose 6-phosphate.

Protein Details

3. Hexokinase-2

General function:: Involved in ATP binding
Specific function:: Main glucose phosphorylating enzyme. May play a regulatory role in both induction and repression of gene expression by glucose
Gene Name:: HXK2
Uniprot ID:: P04807
Molecular weight:: 53942.0

Reactions

ATP + D-hexose → ADP + D-hexose 6-phosphate.
ATP + D-fructose → ADP + D-fructose 1-phosphate

Protein Details

4. Putative hexokinase YLR446W

General function:: Involved in ATP binding
Specific function:: ATP + D-hexose = ADP + D-hexose 6-phosphate
Gene Name:: Not Available
Uniprot ID:: Q06204
Molecular weight:: 48968.80078

Reactions

ATP + D-hexose → ADP + D-hexose 6-phosphate.

Protein Details

5. Hexokinase-1

General function:: Involved in ATP binding
Specific function:: ATP + D-hexose = ADP + D-hexose 6-phosphate
Gene Name:: HXK1
Uniprot ID:: P04806
Molecular weight:: 53737.89844

Reactions

ATP + D-hexose → ADP + D-hexose 6-phosphate.
ATP + D-fructose → ADP + D-fructose 1-phosphate

Protein Details

6. Glucose-6-phosphate isomerase

General function:: Involved in glucose-6-phosphate isomerase activity
Specific function:: D-glucose 6-phosphate = D-fructose 6- phosphate
Gene Name:: PGI1
Uniprot ID:: P12709
Molecular weight:: 61298.89844

Reactions

D-glucose 6-phosphate → D-fructose 6-phosphate.

Protein Details

7. Putative glucokinase-2

General function:: Involved in ATP binding
Specific function:: Putative glucokinase involved in phosphorylation of aldohexoses and glucose uptake. Involved in sporulation. Required for the full activation of the early meiotic inducer IME1
Gene Name:: EMI2
Uniprot ID:: Q04409
Molecular weight:: 55920.30078

Reactions

ATP + D-glucose → ADP + D-glucose 6-phosphate.

Protein Details

8. Glucokinase-1

General function:: Involved in ATP binding
Specific function:: Two isoenzymes, hexokinase-1 and hexokinase-2, can phosphorylate keto- and aldohexoses in yeast, whereas a third isoenzyme, GLK, is specific for aldohexoses. All glucose phosphorylating enzymes are involved in glucose uptake
Gene Name:: GLK1
Uniprot ID:: P17709
Molecular weight:: 55376.89844

Reactions

ATP + D-glucose → ADP + D-glucose 6-phosphate.

Protein Details

9. Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

General function:: Involved in catalytic activity
Specific function:: Synthase catalytic subunit of the trehalose synthase complex that catalyzes the production of trehalose from glucose-6- phosphate and UDP-glucose in a two step process. Can function independently of the complex
Gene Name:: TPS1
Uniprot ID:: Q00764
Molecular weight:: 56147.5

Reactions

UDP-glucose + D-glucose 6-phosphate → UDP + alpha,alpha-trehalose 6-phosphate.

Protein Details

10. Glucose-6-phosphate 1-epimerase

General function:: Involved in isomerase activity
Specific function:: Catalyzes the interconversion between the alpha and beta anomers from at least three hexose 6-phosphate sugars (Glc6P, Gal6P, and Man6P)
Gene Name:: Not Available
Uniprot ID:: Q03161
Molecular weight:: 33955.69922

Reactions

Alpha-D-glucose 6-phosphate → beta-D-glucose 6-phosphate.

Protein Details

11. Phosphoglucomutase YMR278W

General function:: Involved in intramolecular transferase activity, phosphotransferases
Specific function:: This enzyme participates in both the breakdown and synthesis of glucose
Gene Name:: Not Available
Uniprot ID:: Q03262
Molecular weight:: 71068.60156

Reactions

Alpha-D-glucose 1-phosphate → alpha-D-glucose 6-phosphate.

Protein Details

12. Invertase 2

General function:: Involved in hydrolase activity, hydrolyzing O-glycosyl compounds
Specific function:: Hydrolysis of terminal non-reducing beta-D- fructofuranoside residues in beta-D-fructofuranosides
Gene Name:: SUC2
Uniprot ID:: P00724
Molecular weight:: 60638.89844

Reactions

Protein Details

13. Glucose-6-phosphate 1-dehydrogenase

General function:: Involved in glucose-6-phosphate dehydrogenase activity
Specific function:: D-glucose 6-phosphate + NADP(+) = D-glucono- 1,5-lactone 6-phosphate + NADPH
Gene Name:: ZWF1
Uniprot ID:: P11412
Molecular weight:: 57521.10156

Reactions

D-glucose 6-phosphate + NADP(+) → 6-phospho-D-glucono-1,5-lactone + NADPH.

Protein Details

14. Inositol-3-phosphate synthase

General function:: Involved in inositol-3-phosphate synthase activity
Specific function:: D-glucose 6-phosphate = 1D-myo-inositol 3- phosphate
Gene Name:: INO1
Uniprot ID:: P11986
Molecular weight:: 59641.60156

Reactions

D-glucose 6-phosphate → 1D-myo-inositol 3-phosphate.

Structure for #<Compound:0xaea47a3c>

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