{"ymdb_id":"YMDB00469","created_at":"2011-05-29T18:20:33.000Z","updated_at":"2016-09-08T18:35:30.000Z","name":"hexadec-2-enoyl-CoA","cas":"4460-95-1","state":"Solid","melting_point":null,"description":"Hexadec-2-enoyl-CoA is a coenzyme A derivative of hexadec-2-enoate. Fatty acids must be activated with CoA before any chemical modification can be applied. Also fatty acid metabolic intermediates will also exists as CoA derivatives until the CoA is enzymatically cleaved. The fatty acid group is linked to the terminal thoil moiety of CoA.","experimental_water_solubility":null,"experimental_logp_hydrophobicity":"2.319","location":"lipid particle;endoplasmic reticulum;peroxisome;cytoplasm","synthesis_reference":"Al-Arif, Adhid; Blecher, Melvin.  Chemical synthesis of carnitine and coenzyme A esters of the b-substituted intermediates of hexadecanoic acid metabolism.    Biochimica et Biophysica Acta, Lipids and Lipid Metabolism  (1971),  248(3),  416-29.  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J., Swainston, N., Dobson, P., Dunn, W. B., Arga, K. Y., Arvas, M., Bluthgen, N., Borger, S., Costenoble, R., Heinemann, M., Hucka, M., Le Novere, N., Li, P., Liebermeister, W., Mo, M. L., Oliveira, A. P., Petranovic, D., Pettifer, S., Simeonidis, E., Smallbone, K., Spasic, I., Weichart, D., Brent, R., Broomhead, D. S., Westerhoff, H. V., Kirdar, B., Penttila, M., Klipp, E., Palsson, B. O., Sauer, U., Oliver, S. G., Mendes, P., Nielsen, J., Kell, D. B. (2008). \"A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology.\" Nat Biotechnol 26:1155-1160."},{"pubmed_id":9837886,"citation":"Geisbrecht, B. V., Zhu, D., Schulz, K., Nau, K., Morrell, J. C., Geraghty, M., Schulz, H., Erdmann, R., Gould, S. J. (1998). \"Molecular characterization of Saccharomyces cerevisiae Delta3, Delta2-enoyl-CoA isomerase.\" J Biol Chem 273:33184-33191."}],"proteins":[{"created_at":"2011-05-24T21:20:10.000Z","updated_at":"2011-07-22T17:54:57.000Z","name":"Long-chain-fatty-acid--CoA ligase 4","uniprot_id":"P47912","uniprot_name":"LCF4_YEAST","enzyme":true,"transporter":false,"gene_name":"FAA4","num_residues":694,"molecular_weight":"77266.5","theoretical_pi":"6.52","general_function":"Involved in catalytic activity","specific_function":"Esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids. Contributes, with FAA1, to the activation of imported myristate","reactions":[{"id":1512,"direction":"\u003c\u003e","locations":"peroxisome;cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1513,"direction":"\u003c\u003e","locations":"peroxisome;cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1516,"direction":"\u003c\u003e","locations":"cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1517,"direction":"\u003c\u003e","locations":"cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1518,"direction":"\u003c\u003e","locations":"cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1520,"direction":"\u003c\u003e","locations":"peroxisome;cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1521,"direction":"\u003c\u003e","locations":"peroxisome;cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":2380,"direction":"\u003e","locations":"Cytoplasm. Mitochondrion.","altext":"ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA.","export":false,"pw_reaction_id":null,"source":null},{"id":3871,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006387","source":"Smpdb"},{"id":14185,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006609","source":"Smpdb"}],"signal_regions":"None","transmembrane_regions":"None","pdb_id":null,"cellular_location":null,"genbank_gene_id":"Z48744","genbank_protein_id":"732946","gene_card_id":"FAA4","chromosome_location":"chromosome 13","locus":"YMR246W","synonyms":["Fatty acid activator 4","Long-chain acyl-CoA synthetase 4"],"enzyme_classes":["6.2.1.3"],"go_classes":[{"category":"Component","description":" Not Available"},{"category":"Function","description":" catalytic activity"},{"category":"Process","description":" metabolic process"}],"pfams":[{"name":"AMP-binding","identifier":"PF00501"}],"pathways":[{"name":"Fatty acid metabolism","kegg_map_id":"00071"},{"name":"Biosynthesis of unsaturated fatty acids","kegg_map_id":"01040"}],"gene_sequence":"ATGACCGAACAATATTCCGTTGCAGTTGGCGAAGCCGCCAATGAGCATGAAACCGCTCCAAGAAGAAATATCAGGGTTAAAGACCAGCCTTTGATTAGACCCATAAACTCCTCAGCATCTACACTGTACGAATTCGCCCTGGAATGTTTTACCAAGGGTGGTAAGAGAGACGGTATGGCATGGAGAGATATTATAGATATACATGAGACGAAAAAAACCATAGTCAAGAGGGTGGATGGTAAGGATAAGCCCATCGAAAAAACATGGTTGTACTACGAACTGACTCCCTACATAACCATGACATACGAGGAGATGATCTGCGTAATGCACGACATTGGACGTGGGCTGATAAAGATTGGTGTTAAACCTAACGGTGAGAACAAGTTCCACATCTTTGCCTCTACTTCTCACAAGTGGATGAAAACTTTTCTTGGTTGCATGTCACAAGGTATTCCTGTGGTCACCGCGTACGACACTTTGGGTGAGAGCGGTTTGATTCACTCCATGGTGGAAACAGATTCCGTCGCCATTTTCACGGACAACCAGCTGTTGTCCAAATTAGCAGTTCCTTTGAAAACCGCCAAGAACGTAAAATTCGTCATTCACAACGAACCCATCGATCCAAGTGACAAAAGACAAAATGGTAAGCTTTACAAGGCTGCCAAGGATGCTGTTGACAAAATCAAGGAAGTTAGACCGGACATAAAAATCTACAGTTTCGATGAAATTATTGAGATAGGTAAAAAGGCCAAGGACGAGGTTGAATTGCATTTCCCCAAGCCTGAAGATCCAGCTTGTATCATGTACACTTCTGGTTCCACTGGTACACCAAAGGGTGTGGTATTGACACATTACAACATTGTAGCTGGCATTGGTGGTGTGGGCCATAACGTTATCGGATGGATTGGCCCAACAGACCGTATTATCGCATTCTTGCCATTGGCTCATATTTTTGAATTAACCTTTGAATTCGAAGCGTTCTACTGGAATGGTATCCTAGGGTACGCCAATGTCAAGACTTTAACCCCAACTTCTACACGTAATTGCCAAGGTGACCTGATGGAGTTTAAACCTACCGTAATGGTGGGTGTCGCCGCAGTTTGGGAAACAGTGAGAAAAGGTATCCTGGCCAAGATCAACGAATTGCCCGGTTGGTCTCAAACGCTTTTCTGGACTGTCTATGCTTTGAAAGAGAGAAATATACCATGTAGCGGCTTGCTGAGTGGGTTGATCTTCAAGAGAATCAGAGAAGCAACCGGTGGAAACTTAAGGTTTATTCTGAACGGTGGGTCTGCAATCAGCATAGACGCCCAAAAATTCCTCTCCAACCTTCTATGTCCTATGCTCATTGGATATGGGCTAACTGAGGGTGTGGCTAATGCCTGTGTCCTGGAGCCTGAACATTTTGATTACGGTATTGCTGGTGACCTTGTCGGAACTATTACAGCTAAATTGGTGGATGTCGAAGATTTGGGCTATTTTGCCAAGAATAATCAAGGTGAATTGCTGTTTAAGGGTGCACCCATCTGTTCTGAATACTATAAGAATCCTGAAGAAACTGCTGCGGCCTTTACCGATGATGGCTGGTTCCGTACCGGTGATATCGCTGAATGGACCCCCAAGGGACAAGTTAAGATCATTGATAGAAAGAAAGGTTTGGTTAAGACCTTAAATGGTGAGTACATTGCATTGGAAAAATTAGAATCCATTTACAGATCAAATCCTTACGTCCAAAACATCTGTGTCTACGCTGATGAAAACAAAGTTAAGCCTGTCGGTATTGTGGTCCCTAACTTAGGACACTTGTCTAAGCTGGCTATCGAATTAGGTATAATGGTACCAGGTGAAGATGTCGAAAGCTATATCCATGAAAAGAAGCTACAGGATGCCGGTTGCAAAGATATGCTGTCAACTGCCAAATCTCAAGGCTTGAATGGTATTGAATTATTATGTGGCATTGTTTTCTTTGAAGAAGAATGGACTCCAGAAAATGGCCTTGTTACATCCGCCCAAAAATTAAAGAGAAGAGATATTCTAGCGGCTGTCAAGCCAGATGTGGAAAGAGTTTATAAAGAAAACACTTAA","protein_sequence":"MTEQYSVAVGEAANEHETAPRRNIRVKDQPLIRPINSSASTLYEFALECFTKGGKRDGMAWRDIIDIHETKKTIVKRVDGKDKPIEKTWLYYELTPYITMTYEEMICVMHDIGRGLIKIGVKPNGENKFHIFASTSHKWMKTFLGCMSQGIPVVTAYDTLGESGLIHSMVETDSVAIFTDNQLLSKLAVPLKTAKNVKFVIHNEPIDPSDKRQNGKLYKAAKDAVDKIKEVRPDIKIYSFDEIIEIGKKAKDEVELHFPKPEDPACIMYTSGSTGTPKGVVLTHYNIVAGIGGVGHNVIGWIGPTDRIIAFLPLAHIFELTFEFEAFYWNGILGYANVKTLTPTSTRNCQGDLMEFKPTVMVGVAAVWETVRKGILAKINELPGWSQTLFWTVYALKERNIPCSGLLSGLIFKRIREATGGNLRFILNGGSAISIDAQKFLSNLLCPMLIGYGLTEGVANACVLEPEHFDYGIAGDLVGTITAKLVDVEDLGYFAKNNQGELLFKGAPICSEYYKNPEETAAAFTDDGWFRTGDIAEWTPKGQVKIIDRKKNLVKTLNGEYIALEKLESIYRSNPYVQNICVYADENKVKPVGIVVPNLGHLSKLAIELGIMVPGEDVESYIHEKKLQDAVCKDMLSTAKSQGLNGIELLCGIVFFEEEWTPENGLVTSAQKLKRRDILAAVKPDVERVYKENT"},{"created_at":"2011-05-24T21:26:49.000Z","updated_at":"2011-05-29T05:06:16.000Z","name":"3-hydroxyisobutyryl-CoA hydrolase, mitochondrial","uniprot_id":"P28817","uniprot_name":"HIBCH_YEAST","enzyme":true,"transporter":false,"gene_name":"EHD3","num_residues":500,"molecular_weight":"56287.89844","theoretical_pi":"8.5","general_function":"Involved in catalytic activity","specific_function":"Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA. Has an indirect role in endocytic membrane trafficking. May have a function in protein biosynthesis in mitochondrial small ribosomal subunit","reactions":[{"id":2387,"direction":"\u003e","locations":"Mitochondrion","altext":"3-hydroxy-2-methylpropanoyl-CoA + H(2)O = CoA + 3-hydroxy-2-methylpropanoate.","export":false,"pw_reaction_id":null,"source":null},{"id":14164,"direction":"\u003c\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006606","source":"Smpdb"},{"id":14165,"direction":"\u003c\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006610","source":"Smpdb"},{"id":14166,"direction":"\u003c\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006615","source":"Smpdb"},{"id":14167,"direction":"\u003c\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006618","source":"Smpdb"},{"id":14168,"direction":"\u003c\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006622","source":"Smpdb"},{"id":14169,"direction":"\u003c\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006626","source":"Smpdb"},{"id":14170,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006633","source":"Smpdb"},{"id":14171,"direction":"\u003c\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006670","source":"Smpdb"}],"signal_regions":"None","transmembrane_regions":"None","pdb_id":null,"cellular_location":"Mitochondrion","genbank_gene_id":"AY723769","genbank_protein_id":"51830224","gene_card_id":"EHD3","chromosome_location":"chromosome 4","locus":"YDR036C","synonyms":["3-hydroxyisobutyryl-coenzyme A hydrolase","HIB-CoA hydrolase","HIBYL-CoA-H"],"enzyme_classes":["3.1.2.4"],"go_classes":[{"category":"Component","description":" Not Available"},{"category":"Function","description":" catalytic activity"},{"category":"Process","description":" metabolic process"}],"pfams":[{"name":"ECH","identifier":"PF00378"}],"pathways":[{"name":"Valine, leucine and isoleucine degradation","kegg_map_id":"00280"},{"name":"beta-Alanine metabolism","kegg_map_id":"00410"},{"name":"Propanoate metabolism","kegg_map_id":"00640"},{"name":"Fatty acid metabolism","kegg_map_id":"00071"}],"gene_sequence":"ATGCTCAGAAATACGCTAAAATGTGCCCAATTGTCGTCTAAATACGGATTTAAAACTACCACACGTACATTCATGACTACTCAACCCCAGCTAAATGTCACCGACGCACCACCTGTGCTATTTACCGTTCAAGATACAGCTAGAGTTATCACGCTAAATAGGCCCAAAAAGCTCAATGCTTTGAACGCCGAAATGTCAGAATCCATGTTCAAGACTTTGAACGAGTATGCAAAGAGCGATACTACAAACTTAGTCATTTTAAAGTCATCCAACCGACCACGTTCGTTCTGTGCTGGTGGTGATGTAGCTACTGTGGCAATATTCAATTTTAACAAAGAATTTGCCAAGTCCATCAAATTTTTTACTGATGAATATTCTTTGAATTTTCAAATAGCAACTTACTTGAAACCAATTGCTACCTTCATGGACGGTATCACCATGGGTGGCGGCGTTGGTCTATCCATTCACACGCCCTTTAGAATTGCTACAGAAAACACCAAATGGGCCATGCCCGAGATGGACATTGGTTTTTTTCCAGATGTAGGCTCAACTTTTGCTCTCCCTAGAATCGTGACATTGGCTAACTCAAACTCACAAATGGCCCTGTATCTATGTCTTACAGGAGAAGTAGTCACAGGAGCAGACGCTTATATGCTCGGCTTAGCGTCTCATTACGTCAGTAGTGAAAATTTAGATGCTTTGCAGAAAAGATTAGGTGAAATTAGCCCCCCTTTTAATAACGATCCACAATCTGCATACTTCTTCGGGATGGTTAACGAATCCATCGACGAATTCGTATCACCATTACCAAAAGATTATGTTTTCAAGTATTCTAACGAGAAATTAAACGTTATTGAAGCCTGTTTTAACTTGTCTAAAAATGGTACTATTGAAGACATAATGAATAACTTACGTCAATATGAAGGTTCTGCGGAAGGTAAGGCTTTCGCACAAGAAATCAAAACGAAATTGTTAACCAAGTCACCATCCTCTCTTCAAATCGCCTTGAGATTGGTGCAAGAGAATTCCAGAGATCACATAGAATCTGCTATCAAAAGAGACTTATACACAGCGGCTAACATGTGCATGAACCAGGACTCTTTGGTGGAATTCTCTGAAGCCACAAAGCATAAACTTATTGATAAACAAAGGGTCCCGTATCCATGGACAAAGAAGGAACAGTTATTTGTATCTCAGTTGACATCTATCACATCTCCTAAACCATCGCTACCAATGTCATTACTAAGAAATACCTCGAATGTTACTTGGACTCAATATCCCTACCATTCTAAATACCAATTGCCTACAGAACAGGAAATCGCTGCGTATATTGAAAAGAGAACGAATGATGACACTGGCGCCAAAGTTACCGAAAGAGAAGTACTAAATCACTTTGCCAATGTGATTCCTTCTAGAAGAGGGAAACTGGGTATCCAATCGCTATGTAAAATTGTTTGTGAAAGAAAATGTGAAGAAGTTAACGATGGCTTAAGATGGAAATAA","protein_sequence":"MLRNTLKCAQLSSKYGFKTTTRTFMTTQPQLNVTDAPPVLFTVQDTARVITLNRPKKLNALNAEMSESMFKTLNEYAKSDTTNLVILKSSNRPRSFCAGGDVATVAIFNFNKEFAKSIKFFTDEYSLNFQIATYLKPIVTFMDGITMGGGVGLSIHTPFRIATENTKWAMPEMDIGFFPDVGSTFALPRIVTLANSNSQMALYLCLTGEVVTGADAYMLGLASHYVSSENLDALQKRLGEISPPFNNDPQSAYFFGMVNESIDEFVSPLPKDYVFKYSNEKLNVIEACFNLSKNGTIEDIMNNLRQYEGSAEGKAFAQEIKTKLLTKSPSSLQIALRLVQENSRDHIESAIKRDLYTAANMCMNQDSLVEFSEATKHKLIDKQRVPYPWTKKEQLFVSQLTSITSPKPSLPMSLLRNTSNVTWTQYPYHSKYQLPTEQEIAAYIEKRTNDDTGAKVTEREVLNHFANVIPSRRGKLGIQSLCKIVCERKCEEVNDGLRWK"},{"created_at":"2011-05-24T21:41:52.000Z","updated_at":"2011-07-22T17:53:57.000Z","name":"Acyl-coenzyme A oxidase","uniprot_id":"P13711","uniprot_name":"ACOX_YEAST","enzyme":true,"transporter":false,"gene_name":"POX1","num_residues":748,"molecular_weight":"84041.39844","theoretical_pi":"8.7","general_function":"Involved in acyl-CoA dehydrogenase activity","specific_function":"Acyl-CoA + O(2) = trans-2,3-dehydroacyl-CoA + H(2)O(2)","reactions":[{"id":1249,"direction":"\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1250,"direction":"\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1251,"direction":"\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1252,"direction":"\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1253,"direction":"\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1254,"direction":"\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":2392,"direction":"\u003e","locations":"Peroxisome","altext":"Acyl-CoA + O(2) = trans-2,3-dehydroacyl-CoA + H(2)O(2).","export":false,"pw_reaction_id":null,"source":null}],"signal_regions":"None","transmembrane_regions":"None","pdb_id":null,"cellular_location":"Peroxisome","genbank_gene_id":"M27515","genbank_protein_id":"172217","gene_card_id":"POX1","chromosome_location":"chromosome 7","locus":"YGL205W","synonyms":["Acyl-CoA oxidase"],"enzyme_classes":["1.3.3.6"],"go_classes":[{"category":"Component","description":" intracellular membrane-bounded organelle"},{"category":"Component","description":" microbody"},{"category":"Component","description":" peroxisome"},{"category":"Component","description":" organelle"},{"category":"Component","description":" membrane-bounded organelle"},{"category":"Function","description":" catalytic activity"},{"category":"Function","description":" oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor"},{"category":"Function","description":" acyl-CoA oxidase activity"},{"category":"Function","description":" oxidoreductase activity, acting on the CH-CH group of donors"},{"category":"Function","description":" binding"},{"category":"Function","description":" acyl-CoA dehydrogenase activity"},{"category":"Function","description":" nucleoside binding"},{"category":"Function","description":" purine nucleoside binding"},{"category":"Function","description":" adenyl nucleotide binding"},{"category":"Function","description":" FAD or FADH2 binding"},{"category":"Function","description":" oxidoreductase activity"},{"category":"Process","description":" metabolic process"},{"category":"Process","description":" cellular metabolic process"},{"category":"Process","description":" fatty acid catabolic process"},{"category":"Process","description":" fatty acid beta-oxidation"},{"category":"Process","description":" monocarboxylic acid metabolic process"},{"category":"Process","description":" fatty acid metabolic process"},{"category":"Process","description":" oxidation reduction"},{"category":"Process","description":" organic acid metabolic process"},{"category":"Process","description":" oxoacid metabolic process"},{"category":"Process","description":" carboxylic acid metabolic process"}],"pfams":[{"name":"ACOX","identifier":"PF01756"},{"name":"Acyl-CoA_dh_M","identifier":"PF02770"}],"pathways":[{"name":"Fatty acid metabolism","kegg_map_id":"00071"},{"name":"alpha-Linolenic acid metabolism","kegg_map_id":"00592"},{"name":"Biosynthesis of unsaturated fatty acids","kegg_map_id":"01040"}],"gene_sequence":"ATGACGAGACGTACTACTATTAATCCCGATTCGGTGGTTCTGAATCCTCAAAAATTTATCCAGAAAGAAAGGGCGGATTCGAAAATCAAAGTTGACCAAGTTAACACATTTTTAGAGTCATCCCCGGAGAGGAGAACTCTGACGCACGCCTTAATAGACCAAATAGTGAATGATCCTATATTGAAAACTGATACGGACTATTACGATGCTAAAAAAATGCAAGAGAGAGAAATTACTGCCAAAAAAATAGCTAGGCTTGCTAGTTATATGGAGCACGATATCAAAACAGTGCGCAAACACTTTCGCGACACTGACCTGATGAAAGAGTTGCAAGCAAATGATCCAGACAAAGCTTCGCCTTTAACAAACAAAGACCTTTTTATATTCGATAAGAGATTGTCACTTGTAGCAAATATTGATCCTCAATTGGGTACGCGCGTGGGTGTACACTTGGGGCTATTTGGTAATTGTATCAAGGGCAATGGTACTGATGAGCAAATCCGGTATTGGTTGCAGGAGAGAGGTGCCACTTTGATGAAAGGTATATATGGCTGTTTTGCAATGACTGAGTTAGGACATGGTTCCAATGTTGCCCAGCTGCAGACTAGGGCTGTGTACGATAAGCAAAATGATACTTTTGTAATTGATACACCTGATCTAACTGCCACCAAATGGTGGATTGGTGGGGCTGCCCATTCTGCCACGCACGCTGCCGTGTACGCCAGATTGATCGTTGAAGGTAAAGACTACGGTGTAAAAACATTCGTTGTTCCTCTGAGAGACCCTTCGACTTTCCAACTGTTAGCTGGTGTTTCCATAGGGGATATTGGAGCGAAGATGGGTCGTGACGGTATTGATAATGGCTGGATCCAGTTCAGAAACGTAGTTATCCCTAGAGAATTTATGCTAAGTAGATTTACCAAAGTTGTCCGTTCTCCAGATGGTTCAGTCACCGTCAAAACTGAGCCACAATTGGATCAAATTTCTGGTTATAGTGCATTGTTAAGTGGTAGAGTTAACATGGTCATGGATTCATTTAGGTTTGGCTCCAAATTTGCTACTATTGCTGTACGTTACGCGGTTGGTCGTCAGCAATTCGCACCTAGAAAGGGATTGTCTGAAACACAATTAATCGACTATCCCCTTCACCAATATCGTGTTTTACCACAATTGTGTGTTCCATATTTGGTGTCACCTGTAGCTTTTAAGTTAATGGACAACTATTATTCCACTTTGGACGAGTTATACAACGCTTCCTCATCTGCATACAAAGCTGCTCTGGTTACCGTGAGTAAAAAGTTGAAGAATTTATTTATTGATAGCGCCACGTTGAAAGCCACCAATACTTGGTTAATTGCTACACTGATTGATGAGTTGAGACAGACTTGCGGAGGACATGGGTATTCACAGTATAACGGATTTGGTAAAGGCTATGACGACTGGGTGGTTCAGTGCACATGGGAGGGTGATAATAATGTTTTATCTTTAACTTCAGCAAAATCAATATTGAAAAAATTTATCGATTCAGCCACAAAGGGTAGATTTGACAACACACTGGATGTGGACTCATTCTCTTACTTAAAACCTCAGTACATAGGATCTGTGGTTTCTGGAGAAATAAAGAGTGGTTTAAAGGAGTTGGGTGATTATACTGAAATTTGGTCTATCACCTTAATCAAATTACTGGCACATATTGGTACTTTAGTTGAAAAATCAAGAAGTATTGATAGCGTTTCTAAGCTTTTAGTCTTAGTATCCAAATTTCATGCCTTGCGCTGCATGTTGAAAACCTATTACGACAAGTTAAACTCTCGTGATTCACATATTTCCGATGAAATTACAAAGGAATCTATGTGGAATGTTTATAAGTTATTTTCCTTGTATTTTATTGACAAGCATTCCGGAGAATTCCAACAATTCAAGATCTTCACTCCTGATCAGATCTCTAAAGTTGTGCAGCCACAACTATTGGCTCTTTTGCCAATTGTGAGGAAAGACTGTATAGGTCTGACAGACTCCTTTGAATTACCTGACGCGATGTTAAATTCTCCTATAGGTTACTTTGATGGCGATATCTATCACAATTACTTCAATGAAGTTTGCCGCAATAATCCAGTGGAGGCAGATGGGGCAGGGAAGCCTTCTTATCATGCGCTGTTGAGCAGCATGCTCGGTAGAGGTTTCGAATTTGACCAAAAGTTAGGTGGTGCAGCTAATGCGGAAATTTTATCGAAAATAAACAAGTGA","protein_sequence":"MTRRTTINPDSVVLNPQKFIQKERADSKIKVDQVNTFLESSPERRTLTHALIDQIVNDPILKTDTDYYDAKKMQEREITAKKIARLASYMEHDIKTVRKHFRDTDLMKELQANDPDKASPLTNKDLFIFDKRLSLVANIDPQLGTRVGVHLGLFGNCIKGNGTDEQIRYWLQERGATLMKGIYGCFAMTELGHGSNVAQLQTRAVYDKQNDTFVIDTPDLTATKWWIGGAAHSATHAAVYARLIVEGKDYGVKTFVVPLRDPSTFQLLAGVSIGDIGAKMGRDGIDNGWIQFRNVVIPREFMLSRFTKVVRSPDGSVTVKTEPQLDQISGYSALLSGRVNMVMDSFRFGSKFATIAVRYAVGRQQFAPRKGLSETQLIDYPLHQYRVLPQLCVPYLVSPVAFKLMDNYYSTLDELYNASSSAYKAALVTVSKKLKNLFIDSASLKATNTWLIATLIDELRQTCGGHGYSQYNGFGKGYDDWVVQCTWEGDNNVLSLTSAKSILKKFIDSATKGRFDNTLDVDSFSYLKPQYIGSVVSGEIKSGLKELGDYTEIWSITLIKLLAHIGTLVEKSRSIDSVSKLLVLVSKFHALRCMLKTYYDKLNSRDSHISDEITKESMWNVYKLFSLYFIDKHSGEFQQFKIFTPDQISKVVQPQLLALLPIVRKDCIGLTDSFELPDAMLNSPIGYFDGDIYHNYFNEVCRNNPVEADGAGKPSYHALLSSMLGRGFEFDQKLGGAANAEILSKINK"},{"created_at":"2011-05-24T21:43:31.000Z","updated_at":"2011-07-22T17:54:57.000Z","name":"Long-chain-fatty-acid--CoA ligase 1","uniprot_id":"P30624","uniprot_name":"LCF1_YEAST","enzyme":true,"transporter":false,"gene_name":"FAA1","num_residues":700,"molecular_weight":"77865.79688","theoretical_pi":"7.69","general_function":"Involved in catalytic activity","specific_function":"Esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids. It may supplement intracellular myristoyl-CoA pools from exogenous myristate. Preferentially acts on C12:0-C16:0 fatty acids with myristic and pentadecanic acid (C15:0) having the highest activities","reactions":[{"id":1512,"direction":"\u003c\u003e","locations":"peroxisome;cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1513,"direction":"\u003c\u003e","locations":"peroxisome;cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1516,"direction":"\u003c\u003e","locations":"cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1517,"direction":"\u003c\u003e","locations":"cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1518,"direction":"\u003c\u003e","locations":"cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1520,"direction":"\u003c\u003e","locations":"peroxisome;cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1521,"direction":"\u003c\u003e","locations":"peroxisome;cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":2380,"direction":"\u003e","locations":"Cytoplasm. Mitochondrion.","altext":"ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA.","export":false,"pw_reaction_id":null,"source":null},{"id":3871,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006387","source":"Smpdb"}],"signal_regions":"None","transmembrane_regions":"None","pdb_id":null,"cellular_location":null,"genbank_gene_id":"X66194","genbank_protein_id":"3692","gene_card_id":"FAA1","chromosome_location":"chromosome 15","locus":"YOR317W","synonyms":["Fatty acid activator 1","Long-chain acyl-CoA synthetase 1"],"enzyme_classes":["6.2.1.3"],"go_classes":[{"category":"Component","description":" Not Available"},{"category":"Function","description":" catalytic activity"},{"category":"Process","description":" metabolic process"}],"pfams":[{"name":"AMP-binding","identifier":"PF00501"}],"pathways":[{"name":"Fatty acid metabolism","kegg_map_id":"00071"},{"name":"Biosynthesis of unsaturated fatty acids","kegg_map_id":"01040"}],"gene_sequence":"ATGGTTGCTCAATATACCGTTCCAGTTGGGAAAGCCGCCAATGAGCATGAAACTGCTCCAAGAAGAAATTATCAATGCCGCGAGAAGCCGCTCGTCAGACCGCCTAACACAAAGTGTTCCACTGTTTATGAGTTTGTTCTAGAGTGCTTTCAGAAGAACAAAAATTCAAATGCTATGGGTTGGAGGGATGTTAAGGAAATTCATGAAGAATCCAAATCGGTTATGAAAAAAGTTGATGGCAAGGAGACTTCAGTGGAAAAGAAATGGATGTATTATGAACTATCGCATTATCATTATAATTCATTTGACCAATTGACCGATATCATGCATGAAATTGGTCGTGGGTTGGTGAAAATAGGATTAAAGCCTAATGATGATGACAAATTACATCTTTACGCAGCCACTTCTCACAAGTGGATGAAGATGTTCTTAGGAGCGCAGTCTCAAGGTATTCCTGTCGTCACTGCCTACGATACTTTGGGAGAGAAAGGGCTAATTCATTCTTTGGTGCAAACGGGGTCTAAGGCCATTTTTACCGATAACTCTTTATTACCATCCTTGATCAAACCAGTGCAAGCCGCTCAAGACGTAAAATACATAATTCATTTCGATTCCATCAGTTCTGAGGACAGGAGGCAAAGTGGTAAGATCTATCAATCTGCTCATGATGCCATCAACAGAATTAAAGAAGTTAGACCTGATATCAAGACCTTTAGCTTTGACGACATCTTGAAGCTAGGTAAAGAATCCTGTAACGAAATCGATGTTCATCCACCTGGCAAGGATGATCTTTGTTGCATCATGTATACGTCTGGTTCTACAGGTGAGCCAAAGGGTGTTGTCTTGAAACATTCAAATGTTGTCGCAGGTGTTGGTGGTGCAAGTTTGAATGTTTTGAAGTTTGTGGGCAATACCGACCGTGTTATCTGTTTTTTGCCACTAGCTCATATTTTTGAATTGGTTTTCGAACTATTGTCCTTTTATTGGGGGGCCTGCATTGGTTATGCCACCGTAAAAACTTTAACTAGCAGCTCTGTGAGAAATTGTCAAGGTGATTTGCAAGAATTCAAGCCCACAATCATGGTTGGTGTCGCCGCTGTTTGGGAAACAGTGAGAAAAGGGATCTTAAACCAAATTGATAATTTGCCCTTCCTCACCAAGAAAATCTTCTGGACCGCGTATAATACCAAGTTGAACATGCAACGTCTCCACATCCCTGGTGGCGGCGCCTTAGGAAACTTGGTTTTCAAAAAAATCAGAACTGCCACAGGTGGCCAATTAAGATATTTGTTAAACGGTGGTTCTCCAATCAGTCGGGATGCTCAGGAATTCATCACAAATTTAATCTGCCCTATGCTTATTGGTTACGGTTTAACCGAGACATGCGCTAGTACCACCATCTTGGATCCTGCTAATTTTGAACTCGGCGTCGCTGGTGACCTAACAGGTTGTGTTACCGTCAAACTAGTTGATGTTGAAGAATTAGGTTATTTTGCTAAAAACAACCAAGGTGAAGTTTGGATCACAGGTGCCAATGTCACGCCTGAATATTATAAGAATGAGGAAGAAACTTCTCAAGCTTTAACAAGCGATGGTTGGTTCAAGACCGGTGACATCGGTGAATGGGAAGCAAATGGCCATTTGAAAATAATTGACAGGAAGAAAAACTTGGTCAAAACAATGAACGGTGAATATATCGCACTCGAGAAATTAGAGTCCGTTTACAGATCTAACGAATATGTTGCTAACATTTGTGTTTATGCCGACCAATCTAAGACTAAGCCAGTTGGTATTATTGTACCAAATCATGCTCCATTAACGAAGCTTGCTAAAAAGTTGGGAATTATGGAACAAAAAGACAGTTCAATTAATATCGAAAATTATTTGGAGGATGCAAAATTGATTAAAGCTGTTTATTCTGATCTTTTGAAGACAGGTAAAGACCAAGGTTTGGTTGGCATTGAATTACTAGCAGGCATAGTGTTCTTTGACGGCGAATGGACTCCACAAAACGGTTTTGTTACGTCCGCTCAGAAATTGAAAAGAAAAGACATTTTGAATGCTGTCAAAGATAAAGTTGACGCCGTTTATAGTTCGTCTTAA","protein_sequence":"MVAQYTVPVGKAANEHETAPRRNYQCREKPLVRPPNTKCSTVYEFVLECFQKNKNSNAMGWRDVKEIHEESKSVMKKVDGKETSVEKKWMYYELSHYHYNSFDQLTDIMHEIGRGLVKIGLKPNDDDKLHLYAATSHKWMKMFLGAQSQGIPVVTAYDTLGEKGLIHSLVQTGSKAIFTDNSLLPSLIKPVQAAQDVKYIIHFDSISSEDRRQSGKIYQSAHDAINRIKEVRPDIKTFSFDDILKLGKESCNEIDVHPPGKDDLCCIMYTSGSTGEPKGVVLKHSNVVAGVGGASLNVLKFVGNTDRVICFLPLAHIFELVFELLSFYWGACIGYATVKTLTSSSVRNCQGDLQEFKPTIMVGVAAVWETVRKGILNQIDNLPFLTKKIFWTAYNTKLNMQRLHIPGGGALGNLVFKKIRTATGGQLRYLLNGGSPISRDAQEFITNLICPMLIGYGLTETCASTTILDPANFELGVAGDLTGCVTVKLVDVEELGYFAKNNQGEVWITGANVTPEYYKNEEETSQALTSDGWFKTGDIGEWEANGHLKIIDRKKNLVKTMNGEYIALEKLESVYRSNEYVANICVYADQSKTKPVGIIVPNHAPLTKLAKKLGIMEQKDSSINIENYLEDAKLIKAVYSDLLKTGKDQGLVGIELLAGIVFFDGEWTPQNGFVTSAQKLKRKDILNAVKDKVDAVYSSS"},{"created_at":"2011-05-24T21:45:48.000Z","updated_at":"2011-07-22T17:54:57.000Z","name":"Long-chain-fatty-acid--CoA ligase 3","uniprot_id":"P39002","uniprot_name":"LCF3_YEAST","enzyme":true,"transporter":false,"gene_name":"FAA3","num_residues":694,"molecular_weight":"77946.0","theoretical_pi":"9.41","general_function":"Involved in catalytic activity","specific_function":"Esterification, concomitant with transport, of endogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids. This enzyme acts preferentially on C16 and C18 fatty acids with a cis-double bond at C-9-C-10","reactions":[{"id":1512,"direction":"\u003c\u003e","locations":"peroxisome;cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1513,"direction":"\u003c\u003e","locations":"peroxisome;cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1516,"direction":"\u003c\u003e","locations":"cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1517,"direction":"\u003c\u003e","locations":"cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1518,"direction":"\u003c\u003e","locations":"cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1520,"direction":"\u003c\u003e","locations":"peroxisome;cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1521,"direction":"\u003c\u003e","locations":"peroxisome;cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":2380,"direction":"\u003e","locations":"Cytoplasm. Mitochondrion.","altext":"ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA.","export":false,"pw_reaction_id":null,"source":null},{"id":3871,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006387","source":"Smpdb"}],"signal_regions":"None","transmembrane_regions":"None","pdb_id":null,"cellular_location":null,"genbank_gene_id":"AY558110","genbank_protein_id":"45270110","gene_card_id":"FAA3","chromosome_location":"chromosome 9","locus":"YIL009W","synonyms":["Fatty acid activator 3","Long-chain acyl-CoA synthetase 3"],"enzyme_classes":["6.2.1.3"],"go_classes":[{"category":"Component","description":" Not Available"},{"category":"Function","description":" catalytic activity"},{"category":"Process","description":" metabolic process"}],"pfams":[{"name":"AMP-binding","identifier":"PF00501"}],"pathways":[{"name":"Fatty acid metabolism","kegg_map_id":"00071"},{"name":"Biosynthesis of unsaturated fatty acids","kegg_map_id":"01040"},{"name":"Biosynthesis of unsaturated fatty acids (docosanoyl)","kegg_map_id":null},{"name":"Biosynthesis of unsaturated fatty acids (tetracosanoyl-CoA)","kegg_map_id":null}],"gene_sequence":"ATGTCCGAACAACACTCTGTCGCAGTCGGTAAAGCTGCTAATGAGCACGAGACTGCCCCTAGGAGAAATGTTAGAGTCAAGAAGCGGCCCTTAATTAGACCATTGAACTCGTCAGCATCTACGCTGTATGAATTTGCCCTAGAGTGTTTCAACAAGGGTGGAAAACGAGATGGTATGGCTTGGAGAGATGTCATCGAGATTCATGAGACAAAGAAAACCATTGTGAGAAAGGTAGACGGCAAGGATAAATCTATAGAAAAGACATGGCTGTATTATGAAATGTCACCATATAAAATGATGACCTACCAGGAACTGATCTGGGTGATGCACGATATGGGCCGTGGGCTGGCAAAAATAGGCATCAAGCCCAATGGAGAACACAAATTCCACATCTTCGCATCTACTTCCCATAAATGGATGAAGATTTTCCTTGGTTGCATATCCCAGGGTATCCCCGTAGTAACCGCGTATGATACTTTGGGTGAGAGCGGTTTGATTCACTCCATGGTTGAAACCGAGTCTGCTGCTATTTTCACTGATAATCAATTATTGGCTAAAATGATAGTGCCTTTGCAATCTGCTAAAGATATCAAATTTCTTATCCATAACGAACCTATCGACCCCAATGACAGAAGACAAAACGGCAAACTTTACAAGGCTGCTAAGGATGCCATTAATAAGATCAGAGAAGTTAGGCCAGACATAAAAATTTATAGTTTTGAAGAAGTTGTCAAGATAGGTAAAAAAAGTAAAGATGAGGTCAAACTTCATCCACCTGAGCCAAAAGATTTGGCTTGTATCATGTACACCTCGGGCTCGATCAGTGCACCAAAAGGTGTAGTATTGACTCATTATAATATTGTTTCGGGTATCGCTGGTGTAGGTCACAACGTCTTTGGATGGATCGGCTCTACAGACCGTGTTTTGTCGTTCTTGCCATTGGCTCATATTTTTGAACTGGTCTTTGAATTCGAAGCCTTTTACTGGAACGGTATTCTTGGGTACGGTAGTGTTAAGACTTTGACTAATACTTCGACTCGTAATTGTAAGGGTGACCTGGTTGAGTTTAAGCCTACTATTATGATCGGTGTGGCTGCCGTTTGGGAAACTGTGAGAAAAGCTATTTTGGAAAAGATCAGCGATTTAACTCCCGTACTCCAAAAGATTTTTTGGTCTGCCTATAGTATGAAAGAAAAGAGTGTACCATGCACCGGGTTTTTAAGTCGTATGGTCTTCAAGAAAGTCAGACAAGCCACCGGTGGTCATCTTAAGTATATTATGAACGGTGGGTCTGCGATCAGTATTGATGCTCAGAAATTCTTTTCTATCGTCCTGTGTCCTATGATTATCGGTTACGGCCTTACTGAAACAGTTGCGAATGCTTGTGTTTTGGAGCCTGATCATTTCGAATATGGTATAGTTGGTGATCTTGTTGGATCGGTCACTGCCAAATTGGTGGATGTTAAGGACCTAGGTTATTATGCAAAAAACAATCAAGGTGAATTGCTTCTAAAGGGTGCGCCGGTCTGTTCTGAATATTATAAGAATCCAATAGAAACGGCGGTCTCTTTCACTTACGATGGATGGTTTCGTACTGGTGATATTGTTGAATGGACTCCCAAGGGACAACTTAAAATTATTGATAGAAGAAAGAATTTGGTTAAAACCCTAAATGGTGAATATATTGCATTAGAAAAGTTAGAATCTGTTTACAGGTCAAACTCCTATGTGAAAAATATCTGTGTTTATGCCGATGAAAGTAGGGTTAAACCGGTGGGTATTGTGGTACCCAACCCAGGACCCCTATCTAAATTTGCTGTCAAATTGCGTATTATGAAAAAGGGTGAAGACATCGAAAACTATATCCATGACAAAGCATTACGAAATGCTGTTTTCAAAGAGATGATCGCAACAGCCAAATCTCAAGGTTTGGTTGGTATTGAACTATTATGTGGTATTGTTTTCTTTGATGAAGAATGGACACCTGAAAATGGCTTTGTCACATCTGCTCAAAAATTAAAGAGAAGAGAAATCTTAGCCGCTGTTAAATCAGAAGTCGAAAGGGTTTACAAAGAAAATTCTTAG","protein_sequence":"MSEQHSVAVGKAANEHETAPRRNVRVKKRPLIRPLNSSASTLYEFALECFNKGGKRDGMAWRDVIEIHETKKTIVRKVDGKDKSIEKTWLYYEMSPYKMMTYQELIWVMHDMGRGLAKIGIKPNGEHKFHIFASTSHKWMKIFLGCISQGIPVVTAYDTLGESGLIHSMVETESAAIFTDNQLLAKMIVPLQSAKDIKFLIHNEPIDPNDRRQNGKLYKAAKDAINKIREVRPDIKIYSFEEVVKIGKKSKDEVKLHPPEPKDLACIMYTSGSISAPKGVVLTHYNIVSGIAGVGHNVFGWIGSTDRVLSFLPLAHIFELVFEFEAFYWNGILGYGSVKTLTNTSTRNCKGDLVEFKPTIMIGVAAVWETVRKAILEKISDLTPVLQKIFWSAYSMKEKSVPCTGFLSRMVFKKVRQATGGHLKYIMNGGSAISIDAQKFFSIVLCPMIIGYGLTETVANACVLEPDHFEYGIVGDLVGSVTAKLVDVKDLGYYAKNNQGELLLKGAPVCSEYYKNPIETAVSFTYDGWFRTGDIVEWTPKGQLKIIDRRKNLVKTLNGEYIALEKLESVYRSNSYVKNICVYADESRVKPVGIVVPNPGPLSKFAVKLRIMKKGEDIENYIHDKALRNAVFKEMIATAKSQGLVGIELLCGIVFFDEEWTPENGFVTSAQKLKRREILAAVKSEVERVYKENS"},{"created_at":"2011-05-24T21:54:46.000Z","updated_at":"2011-07-22T17:54:57.000Z","name":"Long-chain-fatty-acid--CoA ligase 2","uniprot_id":"P39518","uniprot_name":"LCF2_YEAST","enzyme":true,"transporter":false,"gene_name":"FAA2","num_residues":744,"molecular_weight":"83437.10156","theoretical_pi":"7.82","general_function":"Involved in catalytic activity","specific_function":"Esterification, concomitant with transport, of endogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids. Preferentially acts on C9:0-C13:0 fatty acids although C7:0-C17:0 fatty acids are tolerated","reactions":[{"id":1510,"direction":"\u003c\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1511,"direction":"\u003c\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1512,"direction":"\u003c\u003e","locations":"peroxisome;cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1513,"direction":"\u003c\u003e","locations":"peroxisome;cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1519,"direction":"\u003c\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1520,"direction":"\u003c\u003e","locations":"peroxisome;cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1521,"direction":"\u003c\u003e","locations":"peroxisome;cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":2380,"direction":"\u003e","locations":"Cytoplasm. Mitochondrion.","altext":"ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA.","export":false,"pw_reaction_id":null,"source":null},{"id":3871,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006387","source":"Smpdb"}],"signal_regions":"None","transmembrane_regions":"None","pdb_id":null,"cellular_location":"Cytoplasm. Mitochondrion.","genbank_gene_id":"U18778","genbank_protein_id":"603607","gene_card_id":"FAA2","chromosome_location":"chromosome 5","locus":"YER015W","synonyms":["Fatty acid activator 2","Long-chain acyl-CoA synthetase 2"],"enzyme_classes":["6.2.1.3"],"go_classes":[{"category":"Component","description":" Not Available"},{"category":"Function","description":" catalytic activity"},{"category":"Process","description":" metabolic process"}],"pfams":[{"name":"AMP-binding","identifier":"PF00501"}],"pathways":[{"name":"Fatty acid metabolism","kegg_map_id":"00071"},{"name":"Biosynthesis of unsaturated fatty acids","kegg_map_id":"01040"},{"name":"Biosynthesis of unsaturated fatty acids (docosanoyl)","kegg_map_id":null},{"name":"Biosynthesis of unsaturated fatty acids (tetracosanoyl-CoA)","kegg_map_id":null}],"gene_sequence":"ATGGCCGCTCCAGATTATGCACTTACCGATTTAATTGAATCGGATCCTCGTTTCGAAAGTTTGAAGACAAGATTAGCCGGTTACACCAAAGGCTCTGATGAATATATTGAAGAGCTATACTCTCAATTACCACTGACCAGCTATCCCAGGTACAAAACATTTTTAAAGAAACAGGCGGTTGCCATTTCGAATCCGGATAATGAAGCTGGTTTTAGCTCGATTTATAGGAGTTCTCTTTCTTCTGAAAATCTAGTGAGCTGTGTGGATAAAAACTTAAGAACTGCATACGATCACTTCATGTTTTCTGCAAGGAGATGGCCTCAACGTGACTGTTTAGGTTCAAGGCCAATTGATAAAGCCACAGGCACCTGGGAGGAAACATTCCGTTTCGAGTCGTACTCCACGGTATCTAAAAGATGTCATAATATCGGAAGTGGTATATTGTCTTTGGTAAACACGAAAAGGAAACGTCCTTTGGAAGCCAATGATTTTGTTGTTGCTATCTTATCACACAACAACCCTGAATGGATCCTAACAGATTTGGCCTGTCAGGCCTATTCTCTAACTAACACGGCTTTGTACGAAACATTAGGTCCAAACACCTCCGAGTACATATTGAATTTAACCGAGGCCCCCATTCTGATTTTTGCAAAATCAAATATGTATCATGTATTGAAGATGGTGCCTGATATGAAATTTGTTAATACTTTGGTTTGTATGGATGAATTAACTCATGACGAGCTCCGTATGCTAAATGAATCGTTGCTACCCGTTAAGTGCAACTCTCTCAATGAAAAAATCACATTTTTTTCATTGGAGCAGGTAGAACAAGTTGGTTGCTTTAACAAAATTCCTGCAATTCCACCTACCCCAGATTCCTTGTATACTATTTCGTTTACTTCTGGTACTACAGGTTTACCTAAAGGTGTGGAAATGTCTCACAGAAACATTGCGTCTGGGATAGCATTTGCTTTTTCTACCTTCAGAATACCGCCAGATAAAAGAAACCAACAGTTATATGATATGTGTTTTTTGCCATTGGCTCATATTTTTGAAAGAATGGTTATTGCGTATGATCTAGCCATCGGGTTTGGAATAGGCTTCTTACATAAACCAGACCCAACTGTATTGGTAGAGGATTTGAAGATTTTGAAACCTTACGCGGTTGCCCTGGTTCCTAGAATATTAACACGGTTTGAAGCCGGTATAAAAAACGCTTTGGATAAATCGACTGTCCAGAGGAACGTAGCAAATACTATATTGGATTCTAAATCGGCCAGATTTACCGCAAGAGGTGGTCCAGATAAATCGATTATGAATTTTCTAGTTTATCATCGCGTATTGATTGATAAAATCAGAGACTCTTTAGGTTTGTCCAATAACTCGTTTATAATTACCGGATCAGCTCCCATATCTAAAGATACCTTACTATTTTTAAGAAGTGCCTTGGATATTGGTATAAGACAGGGCTACGGCTTAACTGAAACTTTTGCTGGTGTCTGTTTAAGCGAACCGTTTGAAAAAGATGTCGGATCTTGTGGTGCCATAGGTATTTCTGCAGAATGTAGATTGAAGTCTGTTCCAGAAATGGGTTACCATGCCGACAAGGATTTAAAAGGTGAACTGCAAATTCGTGGCCCACAGGTTTTTGAAAGATATTTTAAAAATCCGAATGAAACTTCAAAAGCCGTTGACCAAGATGGTTGGTTTTCCACGGGAGATGTTGCATTTATCGATGGAAAAGGTCGCATCAGCGTCATTGATCGAGTCAAGAACTTTTTCAAGCTAGCACATGGTGAATATATTGCTCCAGAGAAAATCGAAAATATTTATTTATCATCATGCCCCTATATCACGCAAATATTTGTCTTTGGAGATCCTTTAAAGACATTTTTAGTTGGCATCGTTGGTGTTGATGTTGATGCAGCGCAACCGATTTTAGCTGCAAAGCACCCAGAGGTGAAAACGTGGACTAAGGAAGTGCTAGTAGAAAACTTAAATCGTAATAAAAAGCTAAGGAAGGAATTTTTAAACAAAATTAATAAATGCACCGATGGGCTACAAGGATTCGAAAAATTGCATAACATCAAAGTCGGACTTGAGCCTTTAACTCTCGAGGATGATGTTGTGACGCCAACTTTTAAAATAAAGCGTGCCAAAGCATCAAAATTCTTCAAAGATACATTAGACCAACTATACGCCGAAGGTTCACTAGTCAAGACAGAAAAGCTTTAG","protein_sequence":"MAAPDYALTDLIESDPRFESLKTRLAGYTKGSDEYIEELYSQLPLTSYPRYKTFLKKQAVAISNPDNEAGFSSIYRSSLSSENLVSCVDKNLRTAYDHFMFSARRWPQRDCLGSRPIDKATGTWEETFRFESYSTVSKRCHNIGSGILSLVNTKRKRPLEANDFVVAILSHNNPEWILTDLACQAYSLTNTALYETLGPNTSEYILNLTEAPILIFAKSNMYHVLKMVPDMKFVNTLVCMDELTHDELRMLNESLLPVKCNSLNEKITFFSLEQVEQVGCFNKIPAIPPTPDSLYTISFTSGTTGLPKGVEMSHRNIASGIAFAFSTFRIPPDKRNQQLYDMCFLPLAHIFERMVIAYDLAIGFGIGFLHKPDPTVLVEDLKILKPYAVALVPRILTRFEAGIKNALDKSTVQRNVANTILDSKSARFTARGGPDKSIMNFLVYHRVLIDKIRDSLGLSNNSFIITGSAPISKDTLLFLRSALDIGIRQGYGLTETFAGVCLSEPFEKDVGSCGAIGISAECRLKSVPEMGYHADKDLKGELQIRGPQVFERYFKNPNETSKAVDQDGWFSTGDVAFIDGKGRISVIDRVKNFFKLAHGEYIAPEKIENIYLSSCPYITQIFVFGDPLKTFLVGIVGVDVDAAQPILAAKHPEVKTWTKEVLVENLNRNKKLRKEFLNKINKCTDGLQGFEKLHNIKVGLEPLTLEDDVVTPTFKIKRAKASKFFKDTLDQLYAEGSLVKTEKL"},{"created_at":"2011-05-24T21:56:13.000Z","updated_at":"2011-07-22T17:53:54.000Z","name":"3-ketoacyl-CoA 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3-oxoacyl-CoA","reactions":[{"id":1232,"direction":"\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1233,"direction":"\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1234,"direction":"\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1236,"direction":"\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1237,"direction":"\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1238,"direction":"\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":2399,"direction":"\u003e","locations":"Peroxisome","altext":"Acyl-CoA + acetyl-CoA = CoA + 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hydratase-dehydrogenase-epimerase","uniprot_id":"Q02207","uniprot_name":"FOX2_YEAST","enzyme":true,"transporter":false,"gene_name":"FOX2","num_residues":900,"molecular_weight":"98702.39844","theoretical_pi":"9.46","general_function":"Involved in oxidoreductase activity","specific_function":"Second trifunctional enzyme acting on the beta-oxidation pathway for fatty acids, possessing hydratase-dehydrogenase- epimerase activities. Converts trans-2-enoyl-CoA via D-3- hydroxyacyl-CoA to 3-ketoacyl-CoA","reactions":[{"id":1168,"direction":"\u003c\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1169,"direction":"\u003c\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1170,"direction":"\u003c\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1171,"direction":"\u003c\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1172,"direction":"\u003c\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1173,"direction":"\u003c\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1174,"direction":"\u003c\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1175,"direction":"\u003c\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1176,"direction":"\u003c\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1177,"direction":"\u003c\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1178,"direction":"\u003c\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1179,"direction":"\u003c\u003e","locations":"peroxisome","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":2642,"direction":"\u003e","locations":"Peroxisome","altext":"(3R)-3-hydroxyacyl-CoA = (2E)-2-enoyl-CoA + H(2)O.","export":false,"pw_reaction_id":null,"source":null},{"id":2643,"direction":"\u003e","locations":"Peroxisome","altext":"(R)-3-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA + 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desaturase 1","uniprot_id":"P21147","uniprot_name":"ACO1_YEAST","enzyme":true,"transporter":false,"gene_name":"OLE1","num_residues":510,"molecular_weight":"58402.60156","theoretical_pi":"9.33","general_function":"Involved in stearoyl-CoA 9-desaturase activity","specific_function":"Utilizes O(2) and electrons from the reduced cytochrome b(5) domain to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates (Probable)","reactions":[{"id":1825,"direction":"\u003e","locations":"cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":1981,"direction":"\u003e","locations":"cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":2816,"direction":"\u003e","locations":"Endoplasmic reticulum membrane; Multi-pass membrane protein (Probable)","altext":"Stearoyl-CoA + 2 ferrocytochrome b5 + O(2) + 2 H(+) = oleoyl-CoA + 2 ferricytochrome b5 + 2 H(2)O.","export":false,"pw_reaction_id":null,"source":null}],"signal_regions":"None","transmembrane_regions":"113-133;139-159;256-276;281-301","pdb_id":null,"cellular_location":"Endoplasmic reticulum membrane; Multi-pass membrane protein (Probable)","genbank_gene_id":"J05676","genbank_protein_id":"172064","gene_card_id":"OLE1","chromosome_location":"chromosome 7","locus":"YGL055W","synonyms":["Fatty acid desaturase 1","Stearoyl-CoA desaturase 1"],"enzyme_classes":["1.14.19.1"],"go_classes":[{"category":"Component","description":" cell part"},{"category":"Component","description":" organelle"},{"category":"Component","description":" membrane"},{"category":"Component","description":" membrane-bounded organelle"},{"category":"Component","description":" intracellular membrane-bounded organelle"},{"category":"Component","description":" endoplasmic reticulum"},{"category":"Function","description":" catalytic activity"},{"category":"Function","description":" binding"},{"category":"Function","description":" ion binding"},{"category":"Function","description":" cation binding"},{"category":"Function","description":" metal ion binding"},{"category":"Function","description":" oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"},{"category":"Function","description":" transition metal ion binding"},{"category":"Function","description":" oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"},{"category":"Function","description":" iron ion binding"},{"category":"Function","description":" stearoyl-CoA 9-desaturase activity"},{"category":"Function","description":" oxidoreductase activity"},{"category":"Function","description":" heme binding"},{"category":"Process","description":" organic acid metabolic process"},{"category":"Process","description":" oxoacid metabolic process"},{"category":"Process","description":" metabolic process"},{"category":"Process","description":" carboxylic acid metabolic process"},{"category":"Process","description":" cellular metabolic process"},{"category":"Process","description":" lipid metabolic process"},{"category":"Process","description":" monocarboxylic acid metabolic process"},{"category":"Process","description":" primary metabolic process"},{"category":"Process","description":" fatty acid metabolic process"},{"category":"Process","description":" fatty acid biosynthetic process"},{"category":"Process","description":" oxidation reduction"}],"pfams":[{"name":"Cyt-b5","identifier":"PF00173"},{"name":"FA_desaturase","identifier":"PF00487"}],"pathways":[{"name":"Biosynthesis of unsaturated fatty acids","kegg_map_id":"01040"}],"gene_sequence":"ATGCCAACTTCTGGAACTACTATTGAATTGATTGACGACCAATTTCCAAAGGATGACTCTGCCAGCAGTGGCATTGTCGACGAAGTCGACTTAACGGAAGCTAATATTTTGGCTACTGGTTTGAATAAGAAAGCACCAAGAATTGTCAACGGTTTTGGTTCTTTAATGGGCTCCAAGGAAATGGTTTCCGTGGAATTCGACAAGAAGGGAAACGAAAAGAAGTCCAATTTGGATCGTCTGCTAGAAAAGGACAACCAAGAAAAAGAAGAAGCTAAAACTAAAATTCACATCTCCGAACAACCATGGACTTTGAATAACTGGCACCAACATTTGAACTGGTTGAACATGGTTCTTGTTTGTGGTATGCCAATGATTGGTTGGTACTTCGCTCTCTCTGGTAAAGTACCTTTGCATTTAAACGTTTTCCTTTTCTCCGTTTTCTACTACGCTGTCGGTGGTGTTTCTATTACTGCCGGTTACCATAGATTATGGTCTCACAGATCTTACTCCGCTCACTGGCCATTGAGATTATTCTACGCTATCTTCGGTTGTGCTTCCGTTGAAGGGTCCGCTAAATGGTGGGGCCACTCTCACAGAATTCACCATCGTTACACTGATACCTTGAGAGATCCTTATGACGCTCGTAGAGGTCTATGGTACTCCCACATGGGATGGATGCTTTTGAAGCCAAATCCAAAATACAAGGCTAGAGCTGATATTACCGATATGACTGATGATTGGACCATTAGATTCCAACACAGACACTACATCTTGTTGATGTTATTAACCGCTTTCGTCATTCCAACTCTTATCTGTGGTTACTTTTTCAACGACTATATGGGTGGTTTGATCTATGCCGGTTTTATTCGTGTCTTTGTCATTCAACAAGCTACCTTTTGCATTAACTCCATGGCTCATTACATCGGTACCCAACCATTCGATGACAGAAGAACCCCTCGTGACAACTGGATTACTGCCATTGTTACTTTCGGTGAAGGTTACCATAACTTCCACCACGAATTCCCAACTGATTACAGAAACGCTATTAAGTGGTACCAATACGACCCAACTAAGGTTATCATCTATTTGACTTCTTTAGTTGGTCTAGCATACGACTTGAAGAAATTCTCTCAAAATGCTATTGAAGAAGCCTTGATTCAACAAGAACAAAAGAAGATCAATAAAAAGAAGGCTAAGATTAACTGGGGTCCAGTTTTGACTGATTTGCCAATGTGGGACAAACAAACCTTCTTGGCTAAGTCTAAGGAAAACAAGGGTTTGGTTATCATTTCTGGTATTGTTCACGACGTATCTGGTTATATCTCTGAACATCCAGGTGGTGAAACTTTAATTAAAACTGCATTAGGTAAGGACGCTACCAAGGCTTTCAGTGGTGGTGTCTACCGTCACTCAAATGCCGCTCAAAATGTCTTGGCTGATATGAGAGTGGCTGTTATCAAGGAAAGTAAGAACTCTGCTATTAGAATGGCTAGTAAGAGAGGTGAAATCTACGAAACTGGTAAGTTCTTTTAA","protein_sequence":"MPTSGTTIELIDDQFPKDDSASSGIVDEVDLTEANILATGLNKKAPRIVNGFGSLMGSKEMVSVEFDKKGNEKKSNLDRLLEKDNQEKEEAKTKIHISEQPWTLNNWHQHLNWLNMVLVCGMPMIGWYFALSGKVPLHLNVFLFSVFYYAVGGVSITAGYHRLWSHRSYSAHWPLRLFYAIFGCASVEGSAKWWGHSHRIHHRYTDTLRDPYDARRGLWYSHMGWMLLKPNPKYKARADITDMTDDWTIRFQHRHYILLMLLTAFVIPTLICGYFFNDYMGGLIYAGFIRVFVIQQATFCINSLAHYIGTQPFDDRRTPRDNWITAIVTFGEGYHNFHHEFPTDYRNAIKWYQYDPTKVIIYLTSLVGLAYDLKKFSQNAIEEALIQQEQKKINKKKAKINWGPVLTDLPMWDKQTFLAKSKENKGLVIISGIVHDVSGYISEHPGGETLIKTALGKDATKAFSGGVYRHSNAAQNVLADMRVAVIKESKNSAIRMASKRGEIYETGKFF"},{"created_at":"2011-05-27T08:03:53.000Z","updated_at":"2011-05-27T15:01:29.000Z","name":"Peroxisomal long-chain fatty acid import protein 1","uniprot_id":"P34230","uniprot_name":"PXA2_YEAST","enzyme":false,"transporter":true,"gene_name":"PXA2","num_residues":853,"molecular_weight":"97125.29688","theoretical_pi":"9.25","general_function":"Involved in transport","specific_function":"Involved in the import of activated long-chain fatty acids from the cytosol to the peroxisomal matrix","reactions":[],"signal_regions":"None","transmembrane_regions":"122-142;166-186;269-289;364-384","pdb_id":null,"cellular_location":"Peroxisome membrane; Multi-pass membrane protein","genbank_gene_id":"U93584","genbank_protein_id":"1931633","gene_card_id":"PXA2","chromosome_location":"chromosome 11","locus":"YKL188C","synonyms":["Peroxisomal ABC transporter 2"],"enzyme_classes":[],"go_classes":[{"category":"Component","description":" cell part"},{"category":"Component","description":" membrane"},{"category":"Component","description":" membrane part"},{"category":"Component","description":" intrinsic to membrane"},{"category":"Component","description":" integral to membrane"},{"category":"Function","description":" active transmembrane transporter activity"},{"category":"Function","description":" catalytic activity"},{"category":"Function","description":" hydrolase activity"},{"category":"Function","description":" hydrolase activity, acting on acid anhydrides"},{"category":"Function","description":" hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"},{"category":"Function","description":" primary active transmembrane transporter activity"},{"category":"Function","description":" binding"},{"category":"Function","description":" P-P-bond-hydrolysis-driven transmembrane transporter activity"},{"category":"Function","description":" nucleoside binding"},{"category":"Function","description":" ATPase activity, coupled to transmembrane movement of substances"},{"category":"Function","description":" purine nucleoside binding"},{"category":"Function","description":" pyrophosphatase activity"},{"category":"Function","description":" adenyl nucleotide binding"},{"category":"Function","description":" nucleoside-triphosphatase activity"},{"category":"Function","description":" adenyl ribonucleotide binding"},{"category":"Function","description":" ATPase activity"},{"category":"Function","description":" ATP binding"},{"category":"Function","description":" nucleotide binding"},{"category":"Function","description":" transporter activity"},{"category":"Function","description":" transmembrane transporter activity"},{"category":"Process","description":" transmembrane transport"},{"category":"Process","description":" establishment of localization"},{"category":"Process","description":" transport"}],"pfams":[{"name":"ABC_tran","identifier":"PF00005"},{"name":"ABC_membrane_2","identifier":"PF06472"}],"pathways":[],"gene_sequence":"ATGATCTCAACAGCTTCTGCATTTTATCAGAAGCATAGAGTAAATTTACTGCGTTCTTCATACATAATATTGTTGCTAGCCACGCTTTACAATTCAAATTCCAGTTCTAGTAACAACAAAACTGATAAGAAGGATTCTGAGTCAACGGTTTTAGAAAATAAGAAAATTGAAGAGGGAAAAGAAACCGCAGTAGATAGAGAGGAAGATGAAAGTAGCAAAGAAGAGTTAACGATAGTCTCCAAACATAGCACAGATTCAGAAGATGGTGCAATAATAATTGATAAAGAAAGCAAGACTAATCATAAGGGGGGAGAGCGAAAAGGAAAGGTAGATTTTTTGTTCAAACTTTTGCTTCATGATAAGAAGTGCCTCATTTTATTTATTACACAGGCTATTCTTCTGAACATCAGAACATTGCTGTCTCTTCGTGTGGCTACTTTAGATGGTCAATTAGTGTCCACACTAGTAAGAGCTCAATACGCAAACTTCACAAAGATATTGTTGGGGAAATGGATGATCCTTGGAATTCCCGCCAGTTTTATTAATTCACTGATCAGTTACACGACAAAACTTTGTGCTGTCACTATTAATAGGAAAGTTTCAGACTTTCTACTCTCAAAGTATCTATCTAATCACCATACTTTCTATTCCGTAGCTTCTGCTGAATCTGTTTCAGAAATTCAGGATAATTTGACAAAAGATATTTACACATTTTCAATGAACTCGTCATTATTACTGAATCAGCTATTAAAGCCAATGCTGGATTTGATCCTCTGTTCATTCAAATTATTAACCTCAAACACTAGTGTTATGGGTGAAGGAACTTTGGCACTGGGCTTAATTGTCTACGCCTCCAATTCATTACTAAAATTGATTCAACCGAATTTCACTAGGTTAACTATGGCAAGCGCATCTTTGGAAAGTTGGTTCAGATCTTTACACTCGAATCTACATTCAAGCAATGAAGAAATTGCACTGCTAAGAGGGCAAAAGAGGGAACTAGAAAACGTTGATTATTCATTTTACCGTTTGGTGCTATTTTTAAACAGAGAAATAAAGGCAAGAGCTATTTATGATGTTGCTACTGCATTTGTCATTAAATATACTTGGGGCGCAGCTGGCTTGGTACTATGCTCGATTCCAATATTTTTCAAAAACAAACCTAGTGAAGACACCTTACAGCTTAAGGAACCCGGGAATGATATGACGGCTGATTTCATCACAAATAGAAGATTATTAGTCACTGCATCTAGCTCTATCGGAAGATTTGTGGAACTGAAGAGAAATATACAACAATTACGCGGTATCAGATTGAGATTGAACAAGTTCAATGATTTGTTGGATGCTAATAAAGGTGATGACGAAAAAGAACCAAGAGATGAAAGGTGTATAGTGGAATATGATGATTCAAGGATAAAGTTTGAAAATATTCCTTTAATAACACCTGCCAATCAAGTTCTAGTACCGGAGCTAAGTTTTGATCTGAAGCATGGAAATCATCTACTAATTATTGGGCCCAACGGTTGCGGTAAATCTTCATTATTTCGTATTCTAGGCGGGCTTTGGCCGATAAGGGCGACTCCCAATAAAAATCATCAATCCAAGTTAATAATGCCGCGTAGAACTGTGGATAGAGATTGCGCAATATTTTATTTACCCCAAAGGCCGTATATGGGCAATAGGTCGACATTCAGGGAACAGATTATTTATCCAGACAGTATTGAACAATTCAAAGAAAGATATCACAATGATTATGATCTAGGCGATGCAGATTTAATAAAAATTCTGCAATTATTAGATTTGGAGGATTTAGTCACTGAAAATATGTCACTTCTGCTGGCGCAAAGGACTTCCAAAAATGATTCACAGCAGTTGTCGACGGAAGACAATCAGTCACCATGCGCCATTAAAGTTCGTGATGCATTCAGTATAGTAAGAAATTGGTCCGAAGAATTAACAATTGGTGTCCAACAAAGGTTAGCTATGGCAAGGATGTACTATCATAAACCCAAGTTTGCTGTGCTCGACGAATGTACATCTGCAGTAGCCCCAGAAATGGAACAAAGGATGTACGAAAATGCGCAAAATTTTGGTATCTCGTTAATATCAGTTTGCCACAGGACAAGTTTATGGCATTTTCATAACTATCTGTTAAAATTTGATGGTAAAGGCGGATACCAATTTGGACCGTTTAACCCGAAGGAAAGGTTATGTAATGAAGAAAAACTTCTTGAACTAAATGCCATCTTGGATCAACAGGTGCCACTTTGGGAGCGGAAGTTGAAAGATCTGACAATTGCTAAAGAATCCAACATCATTCGTAAATCAGAAACTAACCTGAATCTTTTTGAAAAGATCGAAGATCCAAAAACGTCCAAATCTAATGCATTGTTTAATGCAAATAAAGGGCAGCGAATCACATCACCTACAGGGCAGGAGACTAGTAAGAGATTACCACTATTTTCCCAACCATCTAGTTCAGCATCATCAAATTTACTAAGAAACAATAAAAGCTTGAACAAAAAAGTTAAAACAAAAAAGGAAGAAGGAAAGGAGAGGTAA","protein_sequence":"MISTASAFYQKHRVNLLRSSYIILLLATLYNSNSSSSNNKTDKKDSESTVLENKKIEEGKETAVDREEDESSKEELTIVSKHSTDSEDGAIIIDKESKTNHKGGERKGKVDFLFKLLLHDKKCLILFITQAILLNIRTLLSLRVATLDGQLVSTLVRAQYANFTKILLGKWMILGIPASFINSLISYTTKLCAVTINRKVSDFLLSKYLSNHHTFYSVASAESVSEIQDNLTKDIYTFSMNSSLLLNQLLKPMLDLILCSFKLLTSNTSVMGEGTLALGLIVYASNSLLKLIQPNFTRLTMASASLESWFRSLHSNLHSSNEEIALLRGQKRELENVDYSFYRLVLFLNREIKARAIYDVATAFVIKYTWGAAGLVLCSIPIFFKNKPSEDTLQLKEPGNDMTADFITNRRLLVTASSSIGRFVELKRNIQQLRGIRLRLNKFNDLLDANKGDDEKEPRDERCIVEYDDSRIKFENIPLITPANQVLVPELSFDLKHGNHLLIIGPNGCGKSSLFRILGGLWPIRATPNKNHQSKLIMPRRTVDRDCAIFYLPQRPYMGNRSTFREQIIYPDSIEQFKERYHNDYDLGDADLIKILQLLDLEDLVTENMSLLLAQRTSKNDSQQLSTEDNQSPCAIKVRDAFSIVRNWSEELTIGVQQRLAMARMYYHKPKFAVLDECTSAVAPEMEQRMYENAQNFGISLISVCHRTSLWHFHNYLLKFDGKGGYQFGPFNPKERLCNEEKLLELNAILDQQVPLWERKLKDLTIAKESNIIRKSETNLNLFEKIEDPKTSKSNALFNANKGQRITSPTGQETSKRLPLFSQPSSSASSNLLRNNKSLNKKVKTKKEEGKER"}]}