Showing Reaction 1411

Acetyl-CoA + water + Oxalacetic acid → hydron + Citric acid + Coenzyme A
Thumb+Thumb+Thumb→Thumb+Thumb+Thumb

Enzymes

  1. Citrate synthase, peroxisomal
  2. Citrate synthase, mitochondrial
  3. Citrate synthase 3

Cellular Locations

  • mitochondrion
  • peroxisome

References

  • Velot, C., Lebreton, S., Morgunov, I., Usher, K. C., Srere, P. A. (1999). "Metabolic effects of mislocalized mitochondrial and peroxisomal citrate synthases in yeast Saccharomyces cerevisiae." Biochemistry 38:16195-16204.10587442
  • Mo, M. L., Palsson, B. O., Herrgard, M. J. (2009). "Connecting extracellular metabolomic measurements to intracellular flux states in yeast." BMC Syst Biol 3:37.19321003
  • Jia, Y. K., Becam, A. M., Herbert, C. J. (1997). "The CIT3 gene of Saccharomyces cerevisiae encodes a second mitochondrial isoform of citrate synthase." Mol Microbiol 24:53-59.9140965