Showing Reaction 1313

Beta-1,4-D-Mannosylchitobiosyldiphosphodolichol + Guanosine diphosphate mannose → alpha-D-mannosyl-beta-D-mannosyldiacetylchitobiosyldiphosphodolichol + hydron + Guanosine diphosphate
Thumb+Thumb→Thumb+Thumb+Thumb

Enzymes

  1. Glycolipid 2-alpha-mannosyltransferase
  2. Alpha-1,2 mannosyltransferase KTR1
  3. Probable mannosyltransferase KTR2
  4. Probable mannosyltransferase KTR3
  5. Probable mannosyltransferase YUR1

Cellular Locations

  • Golgi

References

  • Mo, M. L., Palsson, B. O., Herrgard, M. J. (2009). "Connecting extracellular metabolomic measurements to intracellular flux states in yeast." BMC Syst Biol 3:37.19321003
  • Lussier, M., Sdicu, A. M., Camirand, A., Bussey, H. (1996). "Functional characterization of the YUR1, KTR1, and KTR2 genes as members of the yeast KRE2/MNT1 mannosyltransferase gene family." J Biol Chem 271:11001-11008.8631921
  • Lobsanov, Y. D., Romero, P. A., Sleno, B., Yu, B., Yip, P., Herscovics, A., Howell, P. L. (2004). "Structure of Kre2p/Mnt1p: a yeast alpha1,2-mannosyltransferase involved in mannoprotein biosynthesis." J Biol Chem 279:17921-17931.14752117
  • Romero, P. A., Lussier, M., Sdicu, A. M., Bussey, H., Herscovics, A. (1997). "Ktr1p is an alpha-1,2-mannosyltransferase of Saccharomyces cerevisiae. Comparison of the enzymic properties of soluble recombinant Ktr1p and Kre2p/Mnt1p produced in Pichia pastoris." Biochem J 321 ( Pt 2):289-295.9020857