You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on Yeast Metabolome Database.
Palmityl-CoA + 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol ↔ 6-(alpha-D-glucosaminyl)-O-acyl-1-phosphatidyl-1D-myo-inositol + Coenzyme A
Thumb+6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol6-(alpha-D-glucosaminyl)-O-acyl-1-phosphatidyl-1D-myo-inositol+Thumb

Enzymes

  1. GPI-anchored wall transfer protein 1

Cellular Locations

  • endoplasmic reticulum membrane
  • endoplasmic reticulum

References

  • Huh, W. K., Falvo, J. V., Gerke, L. C., Carroll, A. S., Howson, R. W., Weissman, J. S., O'Shea, E. K. (2003). "Global analysis of protein localization in budding yeast." Nature 425:686-691.14562095
  • Tsukahara, K., Hata, K., Nakamoto, K., Sagane, K., Watanabe, N. A., Kuromitsu, J., Kai, J., Tsuchiya, M., Ohba, F., Jigami, Y., Yoshimatsu, K., Nagasu, T. (2003). "Medicinal genetics approach towards identifying the molecular target of a novel inhibitor of fungal cell wall assembly." Mol Microbiol 48:1029-1042.12753194
  • Galibert, F., Alexandraki, D., Baur, A., Boles, E., Chalwatzis, N., Chuat, J. C., Coster, F., Cziepluch, C., De Haan, M., Domdey, H., Durand, P., Entian, K. D., Gatius, M., Goffeau, A., Grivell, L. A., Hennemann, A., Herbert, C. J., Heumann, K., Hilger, F., Hollenberg, C. P., Huang, M. E., Jacq, C., Jauniaux, J. C., Katsoulou, C., Karpfinger-Hartl, L., et, a. l. .. (1996). "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X." EMBO J 15:2031-2049.8641269
  • Okamoto, M., Yoko-o, T., Umemura, M., Nakayama, K., Jigami, Y. (2006). "Glycosylphosphatidylinositol-anchored proteins are required for the transport of detergent-resistant microdomain-associated membrane proteins Tat2p and Fur4p." J Biol Chem 281:4013-4023.16361252
  • Kim, H., Melen, K., Osterberg, M., von Heijne, G. (2006). "A global topology map of the Saccharomyces cerevisiae membrane proteome." Proc Natl Acad Sci U S A 103:11142-11147.16847258
  • Umemura, M., Okamoto, M., Nakayama, K., Sagane, K., Tsukahara, K., Hata, K., Jigami, Y. (2003). "GWT1 gene is required for inositol acylation of glycosylphosphatidylinositol anchors in yeast." J Biol Chem 278:23639-23647.12714589
  • Miosga, T., Schaaff-Gerstenschlager, I., Chalwatzis, N., Baur, A., Boles, E., Fournier, C., Schmitt, S., Velten, C., Wilhelm, N., Zimmermann, F. K. (1995). "Sequence analysis of a 33.1 kb fragment from the left arm of Saccharomyces cerevisiae chromosome X, including putative proteins with leucine zippers, a fungal Zn(II)2-Cys6 binuclear cluster domain and a putative alpha 2-SCB-alpha 2 binding site." Yeast 11:681-689.7483841