| Identification |
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| Name | S-methylmethionine permease 1 |
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| Synonyms | Not Available |
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| Gene Name | MMP1 |
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| Enzyme Class | Not Available |
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| Biological Properties |
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| General Function | Involved in transport |
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| Specific Function | High-affinity S-methylmethionine (SMM) permease, required for utilization of S-methylmethionine as a sulfur source |
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| Cellular Location | Membrane; Multi-pass membrane protein. Endoplasmic reticulum |
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| SMPDB Pathways | Not Available |
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| KEGG Pathways | Not Available |
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| SMPDB Reactions | Not Available |
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| KEGG Reactions | Not Available |
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| Metabolites | | YMDB ID | Name | View |
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| YMDB00347 | S-Methyl-L-methionine | Show | | YMDB00862 | hydron | Show |
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| GO Classification | | Component |
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| membrane | | membrane part | | intrinsic to membrane | | integral to membrane | | cell part | | Function |
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| transporter activity | | transmembrane transporter activity | | active transmembrane transporter activity | | amine transmembrane transporter activity | | amino acid transmembrane transporter activity | | Process |
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| amine transport | | amino acid transport | | transmembrane transport | | establishment of localization | | transport |
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| Gene Properties |
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| Chromosome Location | chromosome 12 |
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| Locus | YLL061W |
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| Gene Sequence | >1752 bp
ATGGATGAATTTGAATCTACCAAACTTTCGAAGGTTCAGTTTTCCACTAGCGTGTTAAGT
ACGCCTTCGAATGAAGGAAATAATCTAATACACAGATTCAAGAACTCTTTCAAGCGAAAT
GATTCACCAGCGATCCAAGAAGGTTTGCTGTATTCGGAGCTTTCAGAGGAAGAAAAAATA
CAATGGGACTTAGCCAACCAGCCGTATAAAAAGGTCCTAGATCAAAGACACCTGACCATG
ATAGCCATTGGAGGTACTCTAGGGACGGGTCTTTTCATTGGTTTAGGGGAATCACTAGCG
TCCGGACCTGCTTCTTTGCTAATTGGTTTCTTGTTGGTCGGCGCATCTATGCTCTGTGTT
GTTCAGTGTGGGGCCGAACTTTCATGTCAGTACCCTGTTTCCGGCTCCTATGCGCTGCAC
GCCAGTAGATTTATAGACCCATCAGTCGGCTTCAGTATAGGAATTAACTACTTATTGATG
TGGCTCATATCTTACCCTAGCGAGCTGGTAGGATGTTCGCTTACCATCTCTTATTGGGCA
CCATCGGTCAATCCTGCTGCCTGGGTTGCAATCGCGTTCGTTTTAAGCATGCTATTGAAT
CTTTTTGGGGCAAGAGGCTTTGCAGAATCAGAGTTTTATATGTCAATTTTCAAAATTGTG
GCTCTATTCATTTTTATAATTATTGGTATTGTTCTCATTGCAGGTGGTGGGCCTGATTCT
ACTGGATACATCGGCACGAAGTATTGGCACGATCCAGGCTCCTTCGCTGTTCCTGTTTTC
AAAAACCTCTGCAATACTTTTGTTTCGGCAGCATACTCCTTTAGTGGTACAGAAATGGTT
GTTTTAACCAGCACTGAAGCAAGGAGTGTTTCCTCAGTCTCTCGGGCAGCGAAAGGTACG
TTCTGGAGAATTATCATCTTTTATATTGTTACAGTGATTATAATTGGTTGCCTGGTCCCT
TATAATGATCCTCGTCTGATTAGCGGTTCATCCAGTGAGGATATTACTGCTTCCCCGTTT
GTTATTGCCTTGAGCAATACTGGTGCTATGGGAACAAGAGTGTCTCATTTTATGAATGCG
GTCATCTTGATAGCCGTATTTTCTGTTTGCAATTCCTGCGTTTACGCATCCTCTAGATTG
ATTCAGGGTTTGGCGACAGCAGGCCAACTTCCAAAGATCTGCGCTTACATGGACAGGAAT
GGTCGGCCTTTAGTTGGCATGGCTATATGTGGCGCTTTTGGATTGTTAGGCTTTTTGGTT
GTTTCCAAGAACCAGGGTACAGTTTTCACATGGTTGTTTGCGTTGTGTTCCATTTCATTT
TTCACAACTTGGTTCTGTATTTGCTTCTGTCAAGTCAGATTTAGGATGGCAATGAAAGCT
CAAGGAAGGTCAAAGGATGACATTATCTATAGATCGACATTAGGGATATACGGAGGAATT
TTCGGCTGTATCTTAAATGTTCTATTGGTAATTGGAGAAATATATGTATCGGCTGCACCC
GTGGGTAGTCCCAGTTCTGCTGCTAATTTCTTTGAATATTGTATGAGTATTCCCATAATG
ATTGCTGTATATATTGGCCATAGAATTTACCGCAGAGACTGGAGACACTGGTACATCAAG
CGGATGGATATTGACCTCGATAGCGGACATTCGTTAGAGGACTTCGAAGCCACCAAGCTT
GAGAGGGATGAGGATAAGAAATACGTTTCCTCTAAGCCACTTTACTATAGGATCTATCGG
TTTTTCTGTTAA |
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| Protein Properties |
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| Pfam Domain Function | |
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| Protein Residues | 583 |
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| Protein Molecular Weight | 64217.0 |
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| Protein Theoretical pI | 7.97 |
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| Signalling Regions | |
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| Transmembrane Regions | - 78-96
- 102-123
- 144-164
- 183-203
- 216-236
- 255-274
- 299-319
- 357-377
- 403-423
- 429-449
- 474-494
- 506-526
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| Protein Sequence | >S-methylmethionine permease 1
MDEFESTKLSKVQFSTSVLSTPSNEGNNLIHRFKNSFKRNDSPAIQEGLLYSELSEEEKI
QWDLANQPYKKVLDQRHLTMIAIGGTLGTGLFIGLGESLASGPASLLIGFLLVGASMLCV
VQCGAELSCQYPVSGSYALHASRFIDPSVGFSIGINYLLMWLISYPSELVGCSLTISYWA
PSVNPAAWVAIAFVLSMLLNLFGARGFAESEFYMSIFKIVALFIFIIIGIVLIAGGGPDS
TGYIGTKYWHDPGSFAVPVFKNLCNTFVSAAYSFSGTEMVVLTSTEARSVSSVSRAAKGT
FWRIIIFYIVTVIIIGCLVPYNDPRLISGSSSEDITASPFVIALSNTGAMGTRVSHFMNA
VILIAVFSVCNSCVYASSRLIQGLATAGQLPKICAYMDRNGRPLVGMAICGAFGLLGFLV
VSKNQGTVFTWLFALCSISFFTTWFCICFCQVRFRMAMKAQGRSKDDIIYRSTLGIYGGI
FGCILNVLLVIGEIYVSAAPVGSPSSAANFFEYCMSIPIMIAVYIGHRIYRRDWRHWYIK
RMDIDLDSGHSLEDFEATKLERDEDKKYVSSKPLYYRIYRFFC |
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| References |
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| External Links | |
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| General Reference | - Johnston, M., Hillier, L., Riles, L., Albermann, K., Andre, B., Ansorge, W., Benes, V., Bruckner, M., Delius, H., Dubois, E., Dusterhoft, A., Entian, K. D., Floeth, M., Goffeau, A., Hebling, U., Heumann, K., Heuss-Neitzel, D., Hilbert, H., Hilger, F., Kleine, K., Kotter, P., Louis, E. J., Messenguy, F., Mewes, H. W., Hoheisel, J. D., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII." Nature 387:87-90.9169871
- Rouillon, A., Surdin-Kerjan, Y., Thomas, D. (1999). "Transport of sulfonium compounds. Characterization of the s-adenosylmethionine and s-methylmethionine permeases from the yeast Saccharomyces cerevisiae." J Biol Chem 274:28096-28105.10497160
- Huh, W. K., Falvo, J. V., Gerke, L. C., Carroll, A. S., Howson, R. W., Weissman, J. S., O'Shea, E. K. (2003). "Global analysis of protein localization in budding yeast." Nature 425:686-691.14562095
- Kim, H., Melen, K., Osterberg, M., von Heijne, G. (2006). "A global topology map of the Saccharomyces cerevisiae membrane proteome." Proc Natl Acad Sci U S A 103:11142-11147.16847258
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