Identification
NameMalonyl CoA-acyl carrier protein transacylase, mitochondrial
Synonyms
  • MCT
  • Malonyl-CoA:ACP transferase
Gene NameMCT1
Enzyme Class
Biological Properties
General FunctionInvolved in transferase activity
Specific FunctionInvolved in biosynthesis of fatty acids in mitochondria
Cellular LocationMitochondrion
SMPDB Pathways
Fatty acid biosynthesisPW002458 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG Pathways
Fatty acid biosynthesisec00061 Map00061
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
YMDB00045Coenzyme AShow
YMDB00533malonyl-CoAShow
GO Classification
Component
Not Available
Function
catalytic activity
transferase activity
Process
metabolic process
Gene Properties
Chromosome Locationchromosome 15
LocusYOR221C
Gene Sequence>gi|1420511|emb|Z75129.1| S.cerevisiae chromosome XV reading frame ORF YOR221c AGCACTAGAGCATAACTAATACTATAAATTAGACAAAGCAGAAAAAGGGAAAAAGGTTCA TGCTATGATAATGTAAAGAATATGCGTAGAGATATCTATATATCCATTTATACGTTTATA TACTTGCGTGTTTACTTTGTATGGCATAATAACATGTATGTTTGCATTAGGGATTTGTTT TAGTGTATCCAAGAGCGATTAGTATAGAAGGAATGTATGTATGTGTATACGATATTTATA TAAAGGGAAGTTGGCTAATTTTTTGCACACTTTCGTCCTCTTTCCATTTTCAATGAATGC GTAGAAGCACAGACTGGGAGTGGAGAGAGTTCGCAGTTTTGATCTCTTTCTCAATCTTTG TTCTCCTCTGCCGCCTTGTGATAAGCGTCTATAGTTGCTAAAGAGGTGTATTCTATAGTG TCCACTTGGGGACAATTTCTCCGAATAAGGTTATAAATCACATTGCCCGGGCCAAAGCAA ATACTCTTATCAATTTCCACTGGGGTTCCAGAGTTTATGGTATCATAACACATGGTGAAT TGCACAGTCCTGCTTGAACACTTAACGAATCTATCTAGGGCATGATGAATATAGTAAGAT ATATTACCATCTAAGTTAGCTATTATTGGATGGTTCAACTCCATCAACGTGTGAGTTCCG TTTTTCTTTAATATATCCCAAATGTAGTCATAGAGTGGTTCCTGAACGGGCCTCAACACA GTGCTATTATGGAAGGGGATGTTGTATGGGTTAGTTAATTCTGTAATTCTTAAACGCGGG AACCTTAAGTTCAATTCTGTTCTTAAGGACTCTAAATCATCAACCAGACCGGTGACTACA CATTGCTTTACTGAATTTGCATTTGCTACAGAAATGGTATTTTGTGAAGATGATAATAAA TTAGGGGAATTTAGTAGTTTTTGCACTTCTTGCGGTAAATCTGTGGCCCTCGGAGAAGAG AGTGCCCACATTTCAAATTTGTTGGATCTGTTGATATTGTGGGCTACTAAGTACTTTTCA GTAGATGTTACCATTAACTTATTTCTAAAATTAGCAATATCAAAAAGATCCTTTAACGAA AACAGTGAATTAACACTCAGACATGTTAACTCGCCTAGCGAGTGACCCAAAAGGTAACAT TGTTCATTGTCTTTCTTGTCGGGGGAATCGATCTTAGTCATATTTTTTGGTGCTTGATCT TGAGGATCAGAAGGATTCGAGAGTATCTGGTACAATTGATAGAAAAGGTTGGAGCAGACT GCAATGCTTCCGGGGCTGGAAGGGTTCTGGAAGATGTACTGCAATAGATCATTTGATTCC TTGCCGTTCTGACTCAGTATTGTTTGGAATTCTCTTGATTTGTTTCTTATTATCGCTTTT AATATCGAAATGGAGATGGAGGTCCCTTGACCTGGGAAGGTTAGTAGCTTCATACAAACG CTTATATATGTGTACCACGATCAGAAAAGTGCAAAACGCTTTGTTACTACCCTCAGTGTA CGTTATTGAATAGTTCTAATATGCAGCAAGTTACTGGTAAGCTTTGTTTTACCCTTGAGT TCGATACTCAGTTTACTTCCTCCATCGGAGGTTGAAATGCGCCTTGTCATACGGCCAAAA AATGCCATGTAAGAAGATGACACTTTCTGCATTTTGAGTATATTTAAGGGCCTATAATTT TCTTCCAACTTTCTCAAGACAAGCATATTGTGTACTTTCGGTTTAGCAAGCCTTTTTACT TCGTTAACACAAGGCGATGCTAACGTGTGTTTACTGTTTTAGAAGATCGGCATTTATCAA ATGTAAGGACAATGAGACATGGTTGACCAATTAGTTCTTCTCAGATAGGAGTTCTAGTTC TTCTGCATACTACTTAGTCCTCTTCTGTCGTTGACATTCAATTGCTTGTGCATTTCTAAC ATGAAATAGTGGTACTACGAATGCTATTATTCTATGCCAGGCAAATTCCTCTGGAACTTT TTTTTTTTCAGTTTTTTCGTGGTGAGCTTTTTTTGCCTGTCTATCTCGAAAGATCTTGTT GTTGATGACTCAGTGCAGTCGCGATCACTTTCGACTCGACATGCATTTGCAAGTAATTCT GTTATAAAACGTTCTCTTCGTTTTTTCAGTCTGAAGCTCTTCTGCACTTTTTTACTGGGT TAGATTCTATATAGTCAAGTAATTCGAGGTAGCATCAAAGTAAT
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues360
Protein Molecular Weight40706.89844
Protein Theoretical pI6.92
Signalling Regions
  • None
Transmembrane Regions
  • None
Protein Sequence>Malonyl CoA-acyl carrier protein transacylase, mitochondrial MKLLTFPGQGTSISISILKAIIRNKSREFQTILSQNGKESNDLLQYIFQNPSSPGSIAVC SNLFYQLYQILSNPSDPQDQAPKNMTKIDSPDKKDNEQCYLLGHSLGELTCLSVNSLFSL KDLFDIANFRNKLMVTSTEKYLVAHNINRSNKFEMWALSSPRATDLPQEVQKLLNSPNLL SSSQNTISVANANSVKQCVVTGLVDDLESLRTELNLRFPRLRITELTNPYNIPFHNSTVL RPVQEPLYDYIWDILKKNGTHTLMELNHPIIANLDGNISYYIHHALDRFVKCSSRTVQFT MCYDTINSGTPVEIDKSICFGPGNVIYNLIRRNCPQVDTIEYTSLATIDAYHKAAEENKD
References
External Links
ResourceLink
Saccharomyces Genome Database MCT1
Uniprot IDQ12283
Uniprot NameFABD_YEAST
General Reference
  • Galisson, F., Dujon, B. (1996). "Sequence and analysis of a 33 kb fragment from the right arm of chromosome XV of the yeast Saccharomyces cerevisiae." Yeast 12:877-885.8840505
  • Dujon, B., Albermann, K., Aldea, M., Alexandraki, D., Ansorge, W., Arino, J., Benes, V., Bohn, C., Bolotin-Fukuhara, M., Bordonne, R., Boyer, J., Camasses, A., Casamayor, A., Casas, C., Cheret, G., Cziepluch, C., Daignan-Fornier, B., Dang, D. V., de Haan, M., Delius, H., Durand, P., Fairhead, C., Feldmann, H., Gaillon, L., Kleine, K., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV." Nature 387:98-102.9169874
  • Schneider, R., Brors, B., Burger, F., Camrath, S., Weiss, H. (1997). "Two genes of the putative mitochondrial fatty acid synthase in the genome of Saccharomyces cerevisiae." Curr Genet 32:384-388.9388293
  • Huh, W. K., Falvo, J. V., Gerke, L. C., Carroll, A. S., Howson, R. W., Weissman, J. S., O'Shea, E. K. (2003). "Global analysis of protein localization in budding yeast." Nature 425:686-691.14562095
  • Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106