| Identification |
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| Name | Peroxiredoxin TSA2 |
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| Synonyms | - Cytoplasmic thiol peroxidase 2
- cTPx 2
- Thiol-specific antioxidant protein 2
- Thioredoxin peroxidase 2
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| Gene Name | TSA2 |
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| Enzyme Class | |
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| Biological Properties |
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| General Function | Posttranslational modification, protein turnover, chaperones |
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| Specific Function | Reduces peroxides. May play an important role in eliminating peroxides generated during metabolism |
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| Cellular Location | Cytoplasm |
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| SMPDB Pathways | Not Available |
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| KEGG Pathways | Not Available |
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| SMPDB Reactions | Not Available |
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| KEGG Reactions | Not Available |
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| Metabolites | |
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| GO Classification | | Function |
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| peroxiredoxin activity | | antioxidant activity | | catalytic activity | | oxidoreductase activity | | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | | Process |
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| cellular process | | cellular homeostasis | | cell redox homeostasis |
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| Gene Properties |
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| Chromosome Location | Not Available |
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| Locus | |
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| Gene Sequence | >591 bp
ATGGTAGCAGAAGTTCAAAAACAAGCCCCACCATTTAAGAAAACCGCCGTAGTCGACGGT
ATCTTCGAGGAAATTTCACTGGAAAAGTATAAAGGTAAGTACGTTGTTCTAGCTTTTGTC
CCATTGGCTTTTTCATTTGTCTGTCCAACTGAGATTGTTGCGTTTTCCGATGCCGCCAAG
AAATTCGAAGATCAGGGCGCCCAAGTTTTATTTGCCTCCACCGACTCTGAATATTCCTTA
CTGGCATGGACCAACCTTCCCAGAAAAGACGGTGGATTAGGTCCAGTTAAAGTTCCTTTG
CTTGCTGATAAGAATCATTCCTTATCCAGAGACTATGGCGTTTTGATTGAAAAAGAAGGT
ATAGCTTTAAGAGGTTTGTTCATAATCGACCCGAAGGGAATCATTAGACATATCACTATC
AATGATTTATCTGTTGGCAGAAACGTCAATGAAGCTTTGAGATTAGTCGAAGGTTTCCAG
TGGACTGACAAAAATGGTACAGTTTTGCCATGCAACTGGACCCCAGGAGCCGCCACCATC
AAACCTGACGTTAAAGATTCCAAGGAGTATTTCAAAAATGCCAATAATTAA |
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| Protein Properties |
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| Pfam Domain Function | |
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| Protein Residues | 196 |
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| Protein Molecular Weight | 21614.69922 |
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| Protein Theoretical pI | 7.42 |
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| Signalling Regions | |
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| Transmembrane Regions | |
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| Protein Sequence | >Peroxiredoxin TSA2
MVAEVQKQAPPFKKTAVVDGIFEEISLEKYKGKYVVLAFVPLAFSFVCPTEIVAFSDAAK
KFEDQGAQVLFASTDSEYSLLAWTNLPRKDGGLGPVKVPLLADKNHSLSRDYGVLIEKEG
IALRGLFIIDPKGIIRHITINDLSVGRNVNEALRLVEGFQWTDKNGTVLPCNWTPGAATI
KPDVKDSKEYFKNANN |
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| References |
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| External Links | |
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| General Reference | - Jacq, C., Alt-Morbe, J., Andre, B., Arnold, W., Bahr, A., Ballesta, J. P., Bargues, M., Baron, L., Becker, A., Biteau, N., Blocker, H., Blugeon, C., Boskovic, J., Brandt, P., Bruckner, M., Buitrago, M. J., Coster, F., Delaveau, T., del Rey, F., Dujon, B., Eide, L. G., Garcia-Cantalejo, J. M., Goffeau, A., Gomez-Peris, A., Zaccaria, P., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV." Nature 387:75-78.9169867
- Park, S. G., Cha, M. K., Jeong, W., Kim, I. H. (2000). "Distinct physiological functions of thiol peroxidase isoenzymes in Saccharomyces cerevisiae." J Biol Chem 275:5723-5732.10681558
- Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106
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