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Identification
NameHexose transporter HXT8
SynonymsNot Available
Gene NameHXT8
Enzyme ClassNot Available
Biological Properties
General FunctionInvolved in transmembrane transporter activity
Specific FunctionProbable glucose transporter
Cellular LocationMembrane; Multi-pass membrane protein
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
YMDB00286D-GlucoseShow
YMDB00657D-FructoseShow
YMDB00862hydronShow
YMDB00894D-MannoseShow
GO Classification
Component
cell part
membrane
membrane part
intrinsic to membrane
integral to membrane
Function
transporter activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
Process
transmembrane transport
establishment of localization
transport
Gene Properties
Chromosome Locationchromosome 10
LocusYJL214W
Gene Sequence>1710 bp ATGACTGATCGTAAAACCAACTTGCCAGAAGAACCGATTTTCGAAGAGGCAGAAGATGAT GGCTGCCCTTCGATAGAAAATTCTTCACATCTGTCAGTACCTACAGTGGAGGAAAACAAG GACTTTTCCGAGTATAATGGGGAAGAGGCAGAGGAAGTTGTTGTTCCAGAAAAGCCTGCT TCAGCCTATGCTACTGTTTCTATCATGTGTTTATGTATGGCTTTCGGTGGATTTATGTCC GGTTGGGACACAGGTACGATTTCTGGTTTCGTCAATCAGACTGATTTTTTAAGAAGATTT GGTAATTATAGCCATTCCAAGAACACTTACTACTTATCTAATGTGAGAACTGGGTTGATT GTGTCCATCTTCAATGTGGGAAGCGCCATTGGCTGTCTTTTCTTGTCTAAATTGGGTGAT ATTTACGGCCGCTGCATGGGTTTGATTATAGTTATTGTCGTTTATATGGTTGGTATTGTC ATTCAAATTGCCTCTATAGATAAGTGGTATCAGTATTTTATTGGAAGAATTATCGCTGGT ATAGGTGCTGGTTCCATTAGTGTTCTTGCCCCGATGCTTATTTCGGAAACTGCGCCAAAG CATATCAGAGGTACGTTGCTAGCTTGTTGGCAATTGATGGTGACTTTCGCAATTTTCTTG GGTTATTGTACCAATTATGGTACCAAGACTTACTCGAATTCTGTCCAGTGGCGTGTTCCG CTTGGTCTATGTTTTGCATGGGCTATTATTATGATTGGTGGTATGACGTTTGTTCCGGAA TCTCCTCGGTTTTTGGTGCAAGTCGGTAAGATTGAGCAAGCTAAAGCTTCTTTTGCCAAG TCGAACAAGCTTAGTGTTGACGATCCTGCTGTGGTTGCAGAGATTGATCTTCTTGTTGCT GGTGTGGAGGCAGAAGAAGCAATGGGAACTGCTTCATGGAAGGAATTATTTTCGAGAAAG ACTAAAGTTTTTCAACGTTTAACGATGACAGTCATGATTAACTCTCTGCAGCAACTAACC GGTGACAACTATTTCTTCTACTACGGTACTACTATCTTCAAATCTGTCGGTATGAATGAC TCTTTTGAGACTTCAATTGTCTTGGGTATTGTGAATTTTGCTTCTTGCTTCTTTTCACTT TATTCTGTTGATAAGTTGGGCCGTCGTAGATGTCTTTTACTTGGAGCAGCCACCATGACG GCGTGCATGGTTATTTACGCCTCCGTTGGCGTCACAAGACTATATCCGAACGGTAAAAGT GAACCATCATCTAAAGGTGCTGGTAATTGTACGATTGTTTTCACGTGTTTTTACATTTTC TGCTTTTCCTGCACCTGGGGACCTGTATGTTATGTGATTATTTCTGAAACATTTCCATTA AGGGTGAGATCCAAGTGTATGTCCGTTGCAACAGCGGCCAACTTATTGTGGGGGTTCCTA ATCGGGTTTTTCACTCCTTTTATTACTTCGGCAATTAATTTCTACTACGGTTACGTTTTC ATGGGTTGCTTAGCGTTTTCATATTTTTACGTCTTTTTCTTTGTTCCAGAAACAAAAGGT CTAACTTTAGAAGAAGTTGATGAGATGTGGATGGACGGTGTATTACCTTGGAAATCTGAA TCCTGGGTACCAGCTTCTAGAAGGGATGGTGATTATGATAACGAAAAATTACAGCATGAC GAGAAACCCTTCTACAAAAGAATGTTTTAG
Protein Properties
Pfam Domain Function
Protein Residues569
Protein Molecular Weight63492.0
Protein Theoretical pI5.22
Signalling Regions
  • None
Transmembrane Regions
  • 62-82
  • 119-139
  • 146-166
  • 177-197
  • 204-224
  • 239-259
  • 343-359
  • 366-383
  • 391-411
  • 434-454
  • 472-492
  • 494-514
Protein Sequence>Hexose transporter HXT8 MTDRKTNLPEEPIFEEAEDDGCPSIENSSHLSVPTVEENKDFSEYNGEEAEEVVVPEKPA SAYATVSIMCLCMAFGGFMSGWDTGTISGFVNQTDFLRRFGNYSHSKNTYYLSNVRTGLI VSIFNVGSAIGCLFLSKLGDIYGRCMGLIIVIVVYMVGIVIQIASIDKWYQYFIGRIIAG IGAGSISVLAPMLISETAPKHIRGTLLACWQLMVTFAIFLGYCTNYGTKTYSNSVQWRVP LGLCFAWAIIMIGGMTFVPESPRFLVQVGKIEQAKASFAKSNKLSVDDPAVVAEIDLLVA GVEAEEAMGTASWKELFSRKTKVFQRLTMTVMINSLQQLTGDNYFFYYGTTIFKSVGMND SFETSIVLGIVNFASCFFSLYSVDKLGRRRCLLLGAATMTACMVIYASVGVTRLYPNGKS EPSSKGAGNCTIVFTCFYIFCFSCTWGPVCYVIISETFPLRVRSKCMSVATAANLLWGFL IGFFTPFITSAINFYYGYVFMGCLAFSYFYVFFFVPETKGLTLEEVDEMWMDGVLPWKSE SWVPASRRDGDYDNEKLQHDEKPFYKRMF
References
External Links
ResourceLink
Saccharomyces Genome Database HXT8
Uniprot IDP40886
Uniprot NameHXT8_YEAST
GenBank Gene IDZ34098
Genebank Protein ID496948
General Reference
  • Vandenbol, M., Durand, P., Bolle, P. A., Dion, C., Portetelle, D., Hilger, F. (1994). "Sequence analysis of a 40.2 kb DNA fragment located near the left telomere of yeast chromosome X." Yeast 10:1657-1662.7725802
  • Galibert, F., Alexandraki, D., Baur, A., Boles, E., Chalwatzis, N., Chuat, J. C., Coster, F., Cziepluch, C., De Haan, M., Domdey, H., Durand, P., Entian, K. D., Gatius, M., Goffeau, A., Grivell, L. A., Hennemann, A., Herbert, C. J., Heumann, K., Hilger, F., Hollenberg, C. P., Huang, M. E., Jacq, C., Jauniaux, J. C., Katsoulou, C., Karpfinger-Hartl, L., et, a. l. .. (1996). "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X." EMBO J 15:2031-2049.8641269
  • Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106
  • Kim, H., Melen, K., Osterberg, M., von Heijne, G. (2006). "A global topology map of the Saccharomyces cerevisiae membrane proteome." Proc Natl Acad Sci U S A 103:11142-11147.16847258