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Mitochondrial phosphate carrier protein 2 (P40035)

Identification
NameMitochondrial phosphate carrier protein 2
Synonyms
  • Phosphate transport protein 2
  • PTP 2
  • Pi carrier isoform 2
  • mPic 2
Gene NamePIC2
Enzyme ClassNot Available
Biological Properties
General FunctionInvolved in binding
Specific FunctionTransport of phosphate groups from the cytosol to the mitochondrial matrix
Cellular LocationMitochondrion inner membrane; Multi-pass membrane protein
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
YMDB00908HydroxideShow
GO Classification
Component
cell part
membrane
Function
binding
Process
transmembrane transport
establishment of localization
transport
Gene Properties
Chromosome Locationchromosome 5
LocusYER053C
Gene Sequence>903 bp ATGGAGTCCAATAAACAACCACGTAAAATCCAATTATATACGAAAGAGTTTTATGCCACA TGTACCTTAGGTGGTATAATTGCGTGCGGTCCAACACATTCTTCGATCACTCCACTAGAT CTTGTCAAATGTAGGCTACAGGTCAATCCCAAGTTGTATACTTCAAACTTACAAGGGTTC CGTAAGATTATAGCTAATGAAGGCTGGAAGAAAGTATACACTGGGTTTGGTGCTACATTC GTCGGATATTCGCTACAAGGTGCAGGTAAGTATGGTGGTTATGAGTATTTCAAGCATTTG TATTCTAGTTGGTTAAGTCCTGGTGTCACTGTGTACTTGATGGCCTCAGCGACCGCTGAA TTCCTCGCTGATATCATGTTGTGCCCATTTGAAGCTATTAAAGTGAAACAGCAGACTACT ATGCCGCCCTTTTGCAATAACGTTGTTGATGGATGGAAAAAAATGTATGCAGAAAGTGGA GGTATGAAAGCATTTTATAAAGGTATTGTTCCCCTATGGTGCAGACAGATTCCTTACACA ATGTGTAAGTTTACCTCATTCGAAAAAATTGTTCAAAAAATATACAGTGTTTTACCTAAA AAGAAAGAAGAAATGAACGCATTACAGCAAATATCAGTCAGTTTTGTAGGTGGTTATCTG GCAGGTATATTATGTGCTGCAGTCTCACATCCTGCAGACGTTATGGTTTCCAAGATCAAT AGCGAAAGAAAGGCCAACGAGTCCATGTCTGTAGCCTCTAAAAGAATATATCAAAAAATT GGCTTTACTGGGTTGTGGAATGGGTTAATGGTGAGAATTGTCATGATCGGTACTTTGACA AGTTTCCAATGGCTAATTTACGATTCGTTCAAGGCTTATGTAGGCTTACCAACCACCGGT TAG
Protein Properties
Pfam Domain Function
Protein Residues300
Protein Molecular Weight33528.10156
Protein Theoretical pI9.8
Signalling Regions
  • None
Transmembrane Regions
  • 22-42
  • 70-89
  • 108-128
  • 171-192
  • 211-231
  • 260-280
Protein Sequence>Mitochondrial phosphate carrier protein 2 MESNKQPRKIQLYTKEFYATCTLGGIIACGPTHSSITPLDLVKCRLQVNPKLYTSNLQGF RKIIANEGWKKVYTGFGATFVGYSLQGAGKYGGYEYFKHLYSSWLSPGVTVYLMASATAE FLADIMLCPFEAIKVKQQTTMPPFCNNVVDGWKKMYAESGGMKAFYKGIVPLWCRQIPYT MCKFTSFEKIVQKIYSVLPKKKEEMNALQQISVSFVGGYLAGILCAAVSHPADVMVSKIN SERKANESMSVASKRIYQKIGFTGLWNGLMVRIVMIGTLTSFQWLIYDSFKAYVGLPTTG
References
External Links
ResourceLink
Saccharomyces Genome Database PIC2
Uniprot IDP40035
Uniprot NamePIC2_YEAST
GenBank Gene IDU18796
Genebank Protein ID603286
General Reference
  • Dietrich, F. S., Mulligan, J., Hennessy, K., Yelton, M. A., Allen, E., Araujo, R., Aviles, E., Berno, A., Brennan, T., Carpenter, J., Chen, E., Cherry, J. M., Chung, E., Duncan, M., Guzman, E., Hartzell, G., Hunicke-Smith, S., Hyman, R. W., Kayser, A., Komp, C., Lashkari, D., Lew, H., Lin, D., Mosedale, D., Davis, R. W., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome V." Nature 387:78-81.9169868
  • Takabatake, R., Siddique, A. B., Kouchi, H., Izui, K., Hata, S. (2001). "Characterization of a Saccharomyces cerevisiae gene that encodes a mitochondrial phosphate transporter-like protein." J Biochem 129:827-833.11328608
  • Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106
  • Hamel, P., Saint-Georges, Y., de Pinto, B., Lachacinski, N., Altamura, N., Dujardin, G. (2004). "Redundancy in the function of mitochondrial phosphate transport in Saccharomyces cerevisiae and Arabidopsis thaliana." Mol Microbiol 51:307-317.14756774