V-type proton ATPase subunit F (P39111)

Identification
NameV-type proton ATPase subunit F
Synonyms
  • V-ATPase subunit F
  • V-ATPase 14 kDa subunit
  • Vacuolar proton pump subunit F
Gene NameVMA7
Enzyme ClassNot Available
Biological Properties
General FunctionEnergy production and conversion
Specific FunctionSubunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells
Cellular LocationNot Available
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Component
macromolecular complex
protein complex
proton-transporting two-sector ATPase complex, catalytic domain
proton-transporting V-type ATPase, V1 domain
Function
transporter activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
cation transmembrane transporter activity
proton-transporting ATPase activity, rotational mechanism
inorganic cation transmembrane transporter activity
hydrogen ion transporting ATP synthase activity, rotational mechanism
monovalent inorganic cation transmembrane transporter activity
hydrogen ion transmembrane transporter activity
Process
nucleotide metabolic process
purine nucleotide metabolic process
purine nucleotide biosynthetic process
metabolic process
purine nucleoside triphosphate biosynthetic process
purine ribonucleoside triphosphate biosynthetic process
ATP biosynthetic process
ATP synthesis coupled proton transport
nitrogen compound metabolic process
cellular nitrogen compound metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
nucleobase, nucleoside and nucleotide metabolic process
nucleoside phosphate metabolic process
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>357 bp ATGGCTGAGAAACGTACTCTTATAGCTGTGATAGCTGACGAAGATACTACAACTGGTTTA TTGTTAGCCGGGATTGGACAAATCACTCCTGAAACCCAAGAAAAGAACTTTTTTGTTTAC CAAGAAGGTAAGACTACTAAGGAGGAAATCACTGACAAGTTTAATCACTTTACTGAAGAG AGAGACGATATTGCCATCCTTCTAATCAACCAACATATCGCGGAAAACATAAGAGCTAGA GTGGACTCCTTCACCAATGCGTTCCCTGCTATTTTAGAAATTCCATCTAAAGATCATCCC TACGACCCTGAAAAGGACTCTGTATTGAAGAGAGTCAGAAAGTTGTTCGGTGAGTAA
Protein Properties
Pfam Domain Function
Protein Residues118
Protein Molecular Weight13461.09961
Protein Theoretical pI4.68
Signalling Regions
  • None
Transmembrane Regions
  • None
Protein Sequence>V-type proton ATPase subunit F MAEKRTLIAVIADEDTTTGLLLAGIGQITPETQEKNFFVYQEGKTTKEEITDKFNHFTEE RDDIAILLINQHIAENIRARVDSFTNAFPAILEIPSKDHPYDPEKDSVLKRVRKLFGE
References
External Links
ResourceLink
Saccharomyces Genome Database VMA7
Uniprot IDP39111
Uniprot NameVATF_YEAST
GenBank Gene IDU10073
Genebank Protein ID497986
General Reference
  • Nelson, H., Mandiyan, S., Nelson, N. (1994). "The Saccharomyces cerevisiae VMA7 gene encodes a 14-kDa subunit of the vacuolar H(+)-ATPase catalytic sector." J Biol Chem 269:24150-24155.7929071
  • Graham, L. A., Hill, K. J., Stevens, T. H. (1994). "VMA7 encodes a novel 14-kDa subunit of the Saccharomyces cerevisiae vacuolar H(+)-ATPase complex." J Biol Chem 269:25974-25977.7929308
  • Rieger, M., Bruckner, M., Schafer, M., Muller-Auer, S. (1997). "Sequence analysis of 203 kilobases from Saccharomyces cerevisiae chromosome VII." Yeast 13:1077-1090.9290212
  • Tettelin, H., Agostoni Carbone, M. L., Albermann, K., Albers, M., Arroyo, J., Backes, U., Barreiros, T., Bertani, I., Bjourson, A. J., Bruckner, M., Bruschi, C. V., Carignani, G., Castagnoli, L., Cerdan, E., Clemente, M. L., Coblenz, A., Coglievina, M., Coissac, E., Defoor, E., Del Bino, S., Delius, H., Delneri, D., de Wergifosse, P., Dujon, B., Kleine, K., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII." Nature 387:81-84.9169869
  • Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106