Zinc finger protein MSN2 (P33748)

Identification
NameZinc finger protein MSN2
Synonyms
  • Multicopy suppressor of SNF1 protein 2
Gene NameMSN2
Enzyme ClassNot Available
Biological Properties
General Functiontranscription, DNA-templated
Specific FunctionPositive transcriptional factor that acts as a component of the stress responsive system. Recognizes and binds to the stress response element (STRE) which is involved in the response to various forms of stress (heat, oxidative, osmotic, etc.). Involved in the regulation of the CTT1, DDR2, HSP12 genes. May be regulated via WHI2-PSR1 complex phosphatase activity.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: high osmolarity test 1PW002773 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
positive regulation of transcription from RNA polymerase II promoter in response to a hypotonic environment
positive regulation of transcription from RNA polymerase II promoter in response to acidic pH
metal ion binding
positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH
cytosol
positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation
nucleus
positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance
positive regulation of transcription from RNA polymerase II promoter in response to cold
positive regulation of transcription from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase II promoter in response to ethanol
positive regulation of transcription from RNA polymerase II promoter in response to heat stress
positive regulation of transcription from RNA polymerase II promoter in response to freezing
transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation
chromatin remodeling
positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide
replicative cell aging
positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure
core promoter proximal region sequence-specific DNA binding
positive regulation of transcription from RNA polymerase II promoter in response to increased salt
RNA polymerase II transcription factor activity, sequence-specific DNA binding
positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation
age-dependent response to oxidative stress involved in chronological cell aging
regulation of replicative cell aging by regulation of transcription from RNA polymerase II promoter in response to caloric restriction
cellular response to blue light
cellular response to methylmercury
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>2115 bp ATGACGGTCGACCATGATTTCAATAGCGAAGATATTTTATTCCCCATAGAAAGCATGAGT AGTATACAATACGTGGAGAATAATAACCCAAATAATATTAACAACGATGTTATCCCGTAT TCTCTAGATATCAAAAACACTGTCTTAGATAGTGCGGATCTCAATGACATTCAAAATCAA GAAACTTCACTGAATTTGGGGCTTCCTCCACTATCTTTCGACTCTCCACTGCCCGTAACG GAAACGATACCATCCACTACCGATAACAGCTTGCATTTGAAAGCTGATAGCAACAAAAAT CGCGATGCAAGAACTATTGAAAATGATAGTGAAATTAAGAGTACTAATAATGCTAGTGGC TCTGGGGCAAATCAATACACAACTCTTACTTCACCTTATCCTATGAACGACATTTTGTAC AACATGAACAATCCGTTACAATCACCGTCACCTTCATCGGTACCTCAAAATCCGACTATA AATCCTCCCATAAATACAGCAAGTAACGAAACTAATTTATCGCCTCAAACTTCAAATGGT AATGAAACTCTTATATCTCCTCGAGCCCAACAACATACGTCCATTAAAGATAATCGTCTG TCCTTACCTAATGGTGCTAATTCGAATCTTTTCATTGACACTAACCCAAACAATTTGAAC GAAAAACTAAGAAATCAATTGAACTCAGATACAAATTCATATTCTAACTCCATTTCTAAT TCAAACTCCAATTCTACGGGTAATTTAAATTCCAGTTATTTTAATTCACTGAACATAGAC TCCATGCTAGATGATTACGTTTCTAGTGATCTCTTATTGAATGATGATGATGATGACACT AATTTATCACGCCGAAGATTTAGCGACGTTATAACAAACCAATTTCCGTCAATGACAAAT TCGAGGAATTCTATTTCTCACTCTTTGGACCTTTGGAACCATCCGAAAATTAATCCAAGC AATAGAAATACAAATCTCAATATCACTACTAATTCTACCTCAAGTTCCAATGCAAGTCCG AATACCACTACTATGAACGCAAATGCAGACTCAAATATTGCTGGCAACCCGAAAAACAAT GACGCTACCATAGACAATGAGTTGACACAGATTCTTAACGAATATAATATGAACTTCAAC GATAATTTGGGCACATCCACTTCTGGCAAGAACAAATCTGCTTGCCCAAGTTCTTTTGAT GCCAATGCTATGACAAAGATAAATCCAAGTCAGCAATTACAGCAACAGCTAAACCGAGTT CAACACAAGCAGCTCACCTCGTCACATAATAACAGTAGCACTAACATGAAATCCTTCAAC AGCGATCTTTATTCAAGAAGGCAAAGAGCTTCTTTACCCATAATCGATGATTCACTAAGC TACGACCTGGTTAATAAGCAGGATGAAGACCCCAAGAACGATATGCTGCCGAATTCAAAT TTGAGTTCATCTCAACAATTTATCAAACCGTCTATGATTCTTTCAGACAATGCGTCCGTT ATTGCGAAAGTGGCGACTACAGGCTTGAGTAATGATATGCCATTTTTGACAGAGGAAGGT GAACAAAATGCTAATTCTACTCCAAATTTCGATCTTTCCATCACTCAAATGAATATGGCT CCATTATCGCCTGCATCATCATCCTCCACGTCTCTTGCAACAAATCATTTCTATCACCAT TTCCCACAGCAGGGTCACCATACCATGAACTCTAAAATCGGTTCTTCCCTTCGGAGGCGG AAGTCTGCTGTGCCTTTGATGGGTACGGTGCCGCTTACAAATCAACAAAATAATATAAGC AGTAGTAGTGTCAACTCAACTGGCAATGGTGCTGGGGTTACGAAGGAAAGAAGGCCAAGT TACAGGAGAAAATCAATGACACCGTCCAGAAGATCAAGTGTCGTAATAGAATCAACAAAG GAACTCGAGGAGAAACCGTTCCACTGTCACATTTGTCCCAAGAGCTTTAAGCGCAGCGAA CATTTGAAAAGGCATGTGAGATCTGTTCACTCTAACGAACGACCATTTGCTTGTCACATA TGCGATAAGAAATTTAGTAGAAGCGATAATTTGTCGCAACACATCAAGACTCATAAAAAA CATGGAGACATTTAA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues704
Protein Molecular Weight77860.295
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>Zinc finger protein MSN2 MTVDHDFNSEDILFPIESMSSIQYVENNNPNNINNDVIPYSLDIKNTVLDSADLNDIQNQ ETSLNLGLPPLSFDSPLPVTETIPSTTDNSLHLKADSNKNRDARTIENDSEIKSTNNASG SGANQYTTLTSPYPMNDILYNMNNPLQSPSPSSVPQNPTINPPINTASNETNLSPQTSNG NETLISPRAQQHTSIKDNRLSLPNGANSNLFIDTNPNNLNEKLRNQLNSDTNSYSNSISN SNSNSTGNLNSSYFNSLNIDSMLDDYVSSDLLLNDDDDDTNLSRRRFSDVITNQFPSMTN SRNSISHSLDLWNHPKINPSNRNTNLNITTNSTSSSNASPNTTTMNANADSNIAGNPKNN DATIDNELTQILNEYNMNFNDNLGTSTSGKNKSACPSSFDANAMTKINPSQQLQQQLNRV QHKQLTSSHNNSSTNMKSFNSDLYSRRQRASLPIIDDSLSYDLVNKQDEDPKNDMLPNSN LSSSQQFIKPSMILSDNASVIAKVATTGLSNDMPFLTEEGEQNANSTPNFDLSITQMNMA PLSPASSSSTSLATNHFYHHFPQQGHHTMNSKIGSSLRRRKSAVPLMGTVPLTNQQNNIS SSSVNSTGNGAGVTKERRPSYRRKSMTPSRRSSVVIESTKELEEKPFHCHICPKSFKRSE HLKRHVRSVHSNERPFACHICDKKFSRSDNLSQHIKTHKKHGDI
References
External Links
ResourceLink
Saccharomyces Genome Database MSN2
Uniprot IDP33748
Uniprot NameMSN2
General ReferenceNot Available