| Identification |
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| Name | G1/S-specific cyclin CLN2 |
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| Synonyms | Not Available |
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| Gene Name | CLN2 |
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| Enzyme Class | Not Available |
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| Biological Properties |
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| General Function | regulation of cyclin-dependent protein serine/threonine kinase activity |
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| Specific Function | Essential for the control of the cell cycle at the G1/S (start) transition. Interacts with the CDC28 protein kinase to form MPF. |
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| Cellular Location | Not Available |
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| SMPDB Pathways | | Stress-activated signalling pathways: pheromone stress test 1 | PW012843 |    |
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| KEGG Pathways | Not Available |
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| SMPDB Reactions | Not Available |
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| KEGG Reactions | Not Available |
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| Metabolites | |
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| GO Classification | | Function |
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| cyclin-dependent protein kinase holoenzyme complex | | cytoplasm | | cell division | | cyclin-dependent protein serine/threonine kinase regulator activity | | regulation of cyclin-dependent protein serine/threonine kinase activity | | re-entry into mitotic cell cycle after pheromone arrest | | nucleus |
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| Gene Properties |
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| Chromosome Location | Not Available |
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| Locus | |
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| Gene Sequence | >1638 bp
ATGGCTAGTGCTGAACCAAGACCCCGTATGGGACTCGTCATCAATGCTAAACCGGACTAC
TATCCGATTGAGCTATCTAATGCAGAATTACTTTCTCACTTCGAAATGCTGCAAGAATAC
CACCAAGAAATCTCCACCAATGTTATTGCTCAATCATGTAAGTTCAAACCTAATCCAAAA
CTAATAGACCAGCAGCCTGAAATGAACCCCGTGGAAACAAGGTCCAACATTATCACTTTT
TTGTTCGAGCTGTCTGTGGTCACTCGAGTGACAAATGGTATTTTTTTTCATTCAGTTAGA
TTATATGACCGCTATTGTTCCAAGAGAATCGTGTTACGGGACCAAGCCAAATTGGTTGTC
GCTACTTGTCTCTGGTTGGCTGCTAAAACTTGGGGCGGTTGTAATCACATCATCAATAAT
GTAGTCATCCCTACTGGCGGAAGATTTTATGGTCCCAACCCAAGGGCACGTATACCTCGA
CTCTCTGAACTAGTTCATTACTGTGGTGATGGTCAGGTCTTTGATGAATCAATGTTTTTA
CAAATGGAAAGACATATACTAGACACTTTAAATTGGAACATTTATGAACCAATGATCAAT
GATTACGTTTTAAATGTTGATGAAAATTGTTTGATGCAATACGAACTTTATGAAAATCAA
GTTACTTATGACAAACAATGCTCTGAAAAACGTCAGTCTCAATTATCCCAGGATAGTGAT
GCCACTGTAGACGAGAGGCCCTACCAAAACGAAGAAGAAGAAGAAGAAGACTTAAAACTA
AAGATCAAGTTGATTAATTTGAAAAAATTCTTGATTGATGTATCCGCGTGGCAGTACGAC
TTACTTAGATATGAACTTTTCGAAGTATCGCACGGCATATTCTCCATTATCAATCAATTC
ACCAATCAAGACCACGGTCCTTTTTTAATGACTCCAATGACATCAGAAAGCAAAAATGGT
GAAATTTTGAGTACCTTAATGAACGGCATTGTTTCCATTCCTAACTCCTTGATGGAAGTG
TATAAAACGGTCAATGGTGTTCTACCCTTCATTAATCAAGTGAAAGAATATCACTTGGAT
CTACAAAGAAAACTGCAAATTGCATCCAACTTGAACATTTCGAGAAAGCTTACCATATCA
ACCCCATCATGCTCTTTCGAAAATTCAAATAGCACATCCATTCCTTCGCCCGCTTCCTCA
TCTCAAAGCCACACTCCAATGAGAAACATGAGCTCACTCTCTGATAACAGCGTTTTCAGC
CGGAATATGGAACAATCATCACCAATCACTCCAAGTATGTACCAATTTGGTCAGCAGCAG
TCAAACAGTATATGTGGTAGCACCGTTAGTGTGAATAGTCTGGTGAATACAAATAACAAA
CAAAGGATCTACGAACAAATCACGGGTCCTAACAGCAATAACGCAACCAATGATTATATT
GATTTGCTAAACCTAAATGAGTCTAACAAGGAAAACCAAAATCCCGCAACGGCGCATTAC
CTCAATGGGGGCCCACCCAAGACAAGCTTCATTAACCATGGAATGTTCCCCTCGCCAACT
GGGACCATAAATAGCGGTAAATCTAGCAGTGCCTCATCTTTAATTTCTTTTGGTATGGGC
AATACCCAAGTAATATAG |
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| Protein Properties |
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| Pfam Domain Function | Not Available |
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| Protein Residues | 545 |
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| Protein Molecular Weight | 61696.1 |
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| Protein Theoretical pI | Not Available |
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| Signalling Regions | Not Available |
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| Transmembrane Regions | Not Available |
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| Protein Sequence | >G1/S-specific cyclin CLN2
MASAEPRPRMGLVINAKPDYYPIELSNAELLSHFEMLQEYHQEISTNVIAQSCKFKPNPK
LIDQQPEMNPVETRSNIITFLFELSVVTRVTNGIFFHSVRLYDRYCSKRIVLRDQAKLVV
ATCLWLAAKTWGGCNHIINNVVIPTGGRFYGPNPRARIPRLSELVHYCGDGQVFDESMFL
QMERHILDTLNWNIYEPMINDYVLNVDENCLMQYELYENQVTYDKQCSEKRQSQLSQDSD
ATVDERPYQNEEEEEEDLKLKIKLINLKKFLIDVSAWQYDLLRYELFEVSHGIFSIINQF
TNQDHGPFLMTPMTSESKNGEILSTLMNGIVSIPNSLMEVYKTVNGVLPFINQVKEYHLD
LQRKLQIASNLNISRKLTISTPSCSFENSNSTSIPSPASSSQSHTPMRNMSSLSDNSVFS
RNMEQSSPITPSMYQFGQQQSNSICGSTVSVNSLVNTNNKQRIYEQITGPNSNNATNDYI
DLLNLNESNKENQNPATAHYLNGGPPKTSFINHGMFPSPTGTINSGKSSSASSLISFGMG
NTQVI |
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| References |
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| External Links | | Resource | Link |
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| Saccharomyces Genome Database | CLN2 | | Uniprot ID | P20438 | | Uniprot Name | CLN2 |
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| General Reference | Not Available |
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