Identification
NameGuanine nucleotide-binding protein subunit gamma
SynonymsNot Available
Gene NameSTE18
Enzyme ClassNot Available
Biological Properties
General Functionpositive regulation of catalytic activity
Specific FunctionImplicated in the pheromone A- and alpha-factor response pathway. The beta and gamma chains of the putative yeast mating response pathway G protein play a positive role in initiation of the mating response.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: pheromone stress test 1PW012843 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
pheromone-dependent signal transduction involved in conjugation with cellular fusion
cytoplasm
plasma membrane
heterotrimeric G-protein complex
signal transducer activity
heterotrimeric G-protein complex cycle
adenylate cyclase-activating G-protein coupled receptor signaling pathway
cAMP-mediated signaling
positive regulation of catalytic activity
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>333 bp ATGACATCAGTTCAAAACTCTCCACGCTTACAACAACCTCAGGAACAGCAACAGCAACAG CAACAGCTTTCCTTAAAGATAAAACAATTGAAGTTAAAAAGAATCAACGAACTTAACAAT AAACTGAGGAAAGAACTCAGCCGTGAAAGAATTACTGCTTCAAATGCATGTCTTACAATA ATAAACTATACCTCGAATACAAAAGATTATACATTACCAGAACTATGGGGCTACCCCGTA GCAGGATCAAATCATTTTATAGAGGGTTTGAAAAATGCTCAAAAAAATAGCCAAATGTCA AACTCAAATAGTGTTTGTTGTACGCTTATGTAA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues110
Protein Molecular Weight12625.325
Protein Theoretical pINot Available
PDB Fileshow
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>Guanine nucleotide-binding protein subunit gamma MTSVQNSPRLQQPQEQQQQQQQLSLKIKQLKLKRINELNNKLRKELSRERITASNACLTI INYTSNTKDYTLPELWGYPVAGSNHFIEGLKNAQKNSQMSNSNSVCCTLM
References
External Links
ResourceLink
Saccharomyces Genome Database STE18
Uniprot IDP18852
Uniprot NameSTE18
PDB ID
1SCG
General ReferenceNot Available