serine metabolism

SourceIDPathway
PathWhizPW002402 ThumbThumb?image type=greyscaleThumb?image type=simple

Pathway Metabolites

YMDB ID Name
CAS Number
IUPAC Name Formula
Weight
Structure
YMDB00016Glycine
56-40-6
2-aminoacetic acidC2H5NO2
75.0666
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YMDB00076DL-O-Phosphoserine
17885-08-4
2-amino-3-(phosphonooxy)propanoic acidC3H8NO6P
185.0725
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YMDB00080N10-Formyl-THF
2800-34-2
(2S)-2-[(4-{N-[(4-hydroxy-2-imino-1,2,5,6,7,8-hexahydropteridin-6-yl)methyl]formamido}phenyl)formamido]pentanedioic acidC20H23N7O7
473.4393
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YMDB00109Adenosine triphosphate
56-65-5
({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acidC10H16N5O13P3
507.181
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YMDB00110NAD
53-84-9
1-[(2R,3R,4S,5R)-5-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1lambda5-pyridin-1-yliumC21H28N7O14P2
664.433
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YMDB00112L-Serine
56-45-1
(2S)-2-amino-3-hydroxypropanoic acidC3H7NO3
105.0926
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YMDB00139Tetrahydrofolic acid
135-16-0
2-{[4-({[(6S)-4-hydroxy-2-imino-1,2,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acidC19H23N7O6
445.4292
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YMDB00143NADH
58-68-4
[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy})phosphinic acidC21H29N7O14P2
665.441
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YMDB00153Oxoglutaric acid
328-50-7
2-oxopentanedioic acidC5H6O5
146.0981
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YMDB00175Pyruvic acid
127-17-3
2-oxopropanoic acidC3H4O3
88.0621
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YMDB001765,10-Methenyltetrahydrofolic acid
7444-29-3
C20H21N7O6
455.424
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YMDB002605,10-Methylene-THF
31690-11-6
2-({4-[(6aR)-1-hydroxy-3-imino-3H,4H,5H,6H,6aH,7H,8H,9H-imidazo[1,5-f]pteridin-8-yl]phenyl}formamido)pentanedioic acidC20H23N7O6
457.4399
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YMDB00271L-Glutamic acid
56-86-0
(2S)-2-aminopentanedioic acidC5H9NO4
147.1293
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YMDB003413-Phosphoglyceric acid
820-11-1
2-hydroxy-3-(phosphonooxy)propanoic acidC3H7O7P
186.0572
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YMDB00385Formic acid
64-18-6
formic acidCH2O2
46.0254
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YMDB00393Phosphohydroxypyruvic acid
3913-50-6
2-oxo-3-(phosphonooxy)propanoic acidC3H5O7P
184.0414
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YMDB00423Ammonium
14798-03-9
azaniumH4N
18.0385
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YMDB00426NADPH
53-57-6
{[(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-[({[({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-4-hydroxyoxolan-3-yl]oxy}phosphonic acidC21H30N7O17P3
745.4209
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YMDB00427NADP
53-59-8
1-[(2R,3R,4S,5R)-5-[({[({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1lambda5-pyridin-1-yliumC21H29N7O17P3
744.4129
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YMDB004835,6,7,8-Tetrahydrofolic acid
135-16-0
(2S)-2-[(4-{[(2-amino-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acidC19H23N7O6
445.4292
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YMDB0051710-Formyltetrahydrofolic acid
2800-34-2
(2S)-2-{[4-(N-{[(6R)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}formamido)phenyl]formamido}pentanedioic acidC20H23N7O7
473.4393
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YMDB007563-phospho-D-glyceric acid
820-11-1
(2R)-2-hydroxy-3-(phosphonooxy)propanoic acidC3H7O7P
186.0572
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YMDB00848(6R)-5,10-methylenetetrahydrofolic acid
3432-99-3
(2S)-2-({4-[(6aR)-3-amino-1-oxo-1H,2H,5H,6H,6aH,7H,8H,9H-imidazolidino[1,5-f]pteridin-8-yl]phenyl}formamido)pentanedioic acidC20H23N7O6
457.4399
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YMDB00862hydron
12408-02-5
hydronH
1.00794
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YMDB00890water
7732-18-5
waterH2O
18.0153
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YMDB00907phosphate
14265-44-2
phosphoric acidO4P
94.9714
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YMDB00914ADP
58-64-0
[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acidC10H15N5O10P2
427.2011
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YMDB010613-Phosphonatooxypyruvate(3-)2-oxo-3-(phosphonatooxy)propanoateC3H2O7P
181.0175
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YMDB162582-aminoprop-2-enoate2-aminoprop-2-enoateC3H4NO2
86.071
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YMDB162592-iminopropanoate2-iminopropanoateC3H4NO2
86.071
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Pathway Proteins

Uniprot ID Gene Name
Locus
Name Type Metabolites
P37291SHM2
YLR058C
Serine hydroxymethyltransferase, cytosolicEnzyme
P37292SHM1
YBR263W
Serine hydroxymethyltransferase, mitochondrialEnzyme
P40510SER33
YIL074C
D-3-phosphoglycerate dehydrogenase 2Enzyme
P25379CHA1
YCL064C
Catabolic L-serine/threonine dehydrataseEnzyme
P33330SER1
YOR184W
Phosphoserine aminotransferaseEnzyme
P09440MIS1
YBR084W
C-1-tetrahydrofolate synthase, mitochondrialEnzyme
P48015GCV1
YDR019C
Aminomethyltransferase, mitochondrialEnzyme
P42941SER2
YGR208W
Phosphoserine phosphataseEnzyme
P40054SER3
YER081W
D-3-phosphoglycerate dehydrogenase 1Enzyme