lysine metabolism

SourceIDPathway
PathWhizPW002420 ThumbThumb?image type=greyscaleThumb?image type=simple

Pathway Metabolites

YMDB ID Name
CAS Number
IUPAC Name Formula
Weight
Structure
YMDB00019Saccharopine
997-68-2
(2S)-2-{[(5S)-5-amino-5-carboxypentyl]amino}pentanedioic acidC11H20N2O6
276.2863
Thumb
YMDB00045Coenzyme A
85-61-0
{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl-3-({2-[(2-sulfanylethyl)carbamoyl]ethyl}carbamoyl)propoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan-3-yl]oxy}phosphonic acidC21H36N7O16P3S
767.534
Thumb
YMDB00096(2R)-Homocitric acid
3562-74-1
(2R)-2-hydroxybutane-1,2,4-tricarboxylic acidC7H10O7
206.1501
Thumb
YMDB00097Adenosine monophosphate
61-19-8
{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acidC10H14N5O7P
347.2212
Thumb
YMDB00109Adenosine triphosphate
56-65-5
({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acidC10H16N5O13P3
507.181
Thumb
YMDB00110NAD
53-84-9
1-[(2R,3R,4S,5R)-5-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1lambda5-pyridin-1-yliumC21H28N7O14P2
664.433
Thumb
YMDB00142Oxoadipic acid
3184-35-8
2-oxohexanedioic acidC6H8O5
160.1247
Thumb
YMDB00143NADH
58-68-4
[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy})phosphinic acidC21H29N7O14P2
665.441
Thumb
YMDB00153Oxoglutaric acid
328-50-7
2-oxopentanedioic acidC5H6O5
146.0981
Thumb
YMDB00219Pyrophosphate
14000-31-8
(phosphonooxy)phosphonic acidH4O7P2
177.9751
Thumb
YMDB00269but-1-ene-1,2,4-tricarboxylic acid(1Z)-but-1-ene-1,2,4-tricarboxylic acidC7H8O6
188.1348
Thumb
YMDB00271L-Glutamic acid
56-86-0
(2S)-2-aminopentanedioic acidC5H9NO4
147.1293
Thumb
YMDB00305Aminoadipic acid
542-32-5
C6H11NO4
161.1558
Thumb
YMDB00312Acetyl-CoA
72-89-9
{[(2R,3S,4R,5R)-2-({[({[(3R)-3-[(2-{[2-(acetylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-5-(6-amino-9H-purin-9-yl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acidC23H38N7O17P3S
809.571
Thumb
YMDB00330L-Lysine
56-87-1
(2S)-2,6-diaminohexanoic acidC6H14N2O2
146.1876
Thumb
YMDB00346Allysine
1962-83-0
2-amino-6-oxohexanoic acidC6H11NO3
145.1564
Thumb
YMDB00426NADPH
53-57-6
{[(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-[({[({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-4-hydroxyoxolan-3-yl]oxy}phosphonic acidC21H30N7O17P3
745.4209
Thumb
YMDB00427NADP
53-59-8
1-[(2R,3R,4S,5R)-5-[({[({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1lambda5-pyridin-1-yliumC21H29N7O17P3
744.4129
Thumb
YMDB00721L-Allysine
1962-83-0
(2S)-2-amino-6-oxohexanoic acidC6H11NO3
145.1564
Thumb
YMDB00862hydron
12408-02-5
hydronH
1.00794
Thumb
YMDB00890water
7732-18-5
waterH2O
18.0153
Thumb
YMDB00912Carbon dioxide
124-38-9
methanedioneCO2
44.0095
Thumb
YMDB01424hexanoic acid
56-87-1
hexanoic acidC6H12O2
116.1583
Thumb
YMDB16304cis-homoaconitate(1Z)-but-1-ene-1,2,4-tricarboxylateC7H5O6
185.113
Thumb
YMDB16305(1R,2S)-homoisocitrate(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylateC7H7O7
203.128
Thumb

Pathway Proteins

Uniprot ID Gene Name
Locus
Name Type Metabolites
P38998LYS1
YIR034C
Saccharopine dehydrogenase [NAD+, L-lysine-forming]Enzyme
P38999LYS9
YNR050C
Saccharopine dehydrogenase [NADP+, L-glutamate-forming]Enzyme
Q12122LYS21
YDL131W
Homocitrate synthase, mitochondrialEnzyme
P48570LYS20
YDL182W
Homocitrate synthase, cytosolic isozymeEnzyme
P07702LYS2
YBR115C
L-aminoadipate-semialdehyde dehydrogenaseEnzyme
P40495LYS12
YIL094C
Homoisocitrate dehydrogenase, mitochondrialEnzyme
P49367LYS4
YDR234W
Homoaconitase, mitochondrialEnzyme