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Lipoic acid metabolism

SourceIDPathway
PathWhizPW002499 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG00785 Map00785

Pathway Metabolites

YMDB ID Name
CAS Number
IUPAC Name Formula
Weight
Structure
YMDB00097Adenosine monophosphate
61-19-8
{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acidC10H14N5O7P
347.2212
Thumb
YMDB00109Adenosine triphosphate
56-65-5
({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acidC10H16N5O13P3
507.181
Thumb
YMDB00219Pyrophosphate
14000-31-8
(phosphonooxy)phosphonic acidH4O7P2
177.9751
Thumb
YMDB00239lipoyl-AMP{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[5-(1,2-dithiolan-3-yl)pentanoyl]oxy})phosphinic acidC18H26N5O8PS2
535.532
Thumb
YMDB00297S-Adenosylmethionine
29908-03-0
[(3S)-3-amino-3-carboxypropyl]({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl})methylsulfaniumC15H23N6O5S
399.445
Thumb
YMDB00318L-Methionine
63-68-3
(2S)-2-amino-4-(methylsulfanyl)butanoic acidC5H11NO2S
149.211
Thumb
YMDB00334Lipoic acid
1077-28-7
5-[(3R)-1,2-dithiolan-3-yl]pentanoic acidC8H14O2S2
206.326
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YMDB00438S-Adenosyl-L-methionine
29908-03-0
[(3S)-3-amino-3-carboxypropyl]({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl})methylsulfaniumC15H23N6O5S
399.445
Thumb
YMDB005032'-Deoxyadenosine(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-olC10H13N5O3
251.2419
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Pathway Proteins

Uniprot ID Gene Name
Locus
Name Type Metabolites
P32875LIP5
YOR196C
Lipoyl synthase, mitochondrialEnzyme
P47051AIM22
YJL046W
Putative lipoate-protein ligase AEnzyme
Q06005LIP2
Octanoyltransferase, mitochondrialEnzymeNot Available