Riboflavin metabolism

SourceIDPathway
PathWhizPW002443 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG00740 Map00740

Pathway Metabolites

YMDB ID Name
CAS Number
IUPAC Name Formula
Weight
Structure
YMDB00085Flavin Mononucleotide
146-17-8
{[(2R,3S,4S)-5-{7,8-dimethyl-2,4-dioxo-2H,3H,4H,10H-benzo[g]pteridin-10-yl}-2,3,4-trihydroxypentyl]oxy}phosphonic acidC17H21N4O9P
456.3438
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YMDB00109Adenosine triphosphate
56-65-5
({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acidC10H16N5O13P3
507.181
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YMDB00110NAD
53-84-9
1-[(2R,3R,4S,5R)-5-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1lambda5-pyridin-1-yliumC21H28N7O14P2
664.433
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YMDB00143NADH
58-68-4
[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy})phosphinic acidC21H29N7O14P2
665.441
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YMDB001472,5-Diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine{[(2R,3S,4R,5R)-5-[(2,5-diamino-6-oxo-1,6-dihydropyrimidin-4-yl)amino]-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acidC9H16N5O8P
353.2258
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YMDB00155Quinone
106-51-4
cyclohexa-2,5-diene-1,4-dioneC6H4O2
108.0948
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YMDB001635-Amino-6-(5'-phosphoribosylamino)uracil{[(2R,3S,4R,5R)-5-[(5-amino-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino]-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acidC9H15N4O9P
354.2106
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YMDB001715-Amino-6-ribitylamino uracil5-amino-6-[(2,3,4,5-tetrahydroxypentyl)amino]-1,2,3,4-tetrahydropyrimidine-2,4-dioneC9H16N4O6
276.2465
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YMDB00208(2S)-2-Hydroxy-3-oxobutyl phosphate[(2S)-2-hydroxy-3-oxobutoxy]phosphonic acidC4H9O6P
184.0844
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YMDB00219Pyrophosphate
14000-31-8
(phosphonooxy)phosphonic acidH4O7P2
177.9751
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YMDB00296FAD
146-14-5
{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}[({[(2R,3S,4S)-5-{7,8-dimethyl-2,4-dioxo-2H,3H,4H,10H-benzo[g]pteridin-10-yl}-2,3,4-trihydroxypentyl]oxy}(hydroxy)phosphoryl)oxy]phosphinic acidC27H33N9O15P2
785.5497
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YMDB003005-Amino-6-(5'-phosphoribitylamino)uracil({5-[(5-amino-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino]-2,3,4-trihydroxypentyl}oxy)phosphonic acidC9H17N4O9P
356.2264
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YMDB00385Formic acid
64-18-6
formic acidCH2O2
46.0254
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YMDB004242,5-Diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone{[(2R,3S,4S)-5-[(2,5-diamino-6-oxo-1,6-dihydropyrimidin-4-yl)amino]-2,3,4-trihydroxypentyl]oxy}phosphonic acidC9H18N5O8P
355.2417
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YMDB004255-Amino-6-(5-phospho-D-ribitylamino)uracil{[(2R,3S,4S)-5-[(5-amino-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino]-2,3,4-trihydroxypentyl]oxy}phosphonic acidC9H17N4O9P
356.2264
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YMDB004562-Hydroxy-3-oxobutyl phosphate(2-hydroxy-3-oxobutoxy)phosphonic acidC4H9O6P
184.0844
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YMDB00534Riboflavin
83-88-5
7,8-dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]-2H,3H,4H,10H-benzo[g]pteridine-2,4-dioneC17H20N4O6
376.3639
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YMDB00558GTP
86-01-1
({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acidC10H16N5O14P3
523.1804
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YMDB00597FADH2
1910-41-4
{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}[({[(2R,3S,4S)-5-{7,8-dimethyl-2,4-dioxo-1H,2H,3H,4H,5H,10H-benzo[g]pteridin-10-yl}-2,3,4-trihydroxypentyl]oxy}(hydroxy)phosphoryl)oxy]phosphinic acidC27H35N9O15P2
787.5656
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YMDB00686FMNH2{[(2R,3S,4S)-5-{7,8-dimethyl-2,4-dioxo-1H,2H,3H,4H,5H,10H-benzo[g]pteridin-10-yl}-2,3,4-trihydroxypentyl]oxy}phosphonic acidC17H23N4O9P
458.3597
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YMDB007655-Amino-6-(D-ribitylamino)uracil5-amino-6-{[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]amino}-1,2,3,4-tetrahydropyrimidine-2,4-dioneC9H16N4O6
276.2465
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YMDB007666,7-Dimethyl-8-(1-D-ribityl)lumazine
5118-16-1
6,7-dimethyl-8-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]-2,3,4,8-tetrahydropteridine-2,4-dioneC13H18N4O6
326.3052
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YMDB00862hydron
12408-02-5
hydronH
1.00794
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YMDB00890water
7732-18-5
waterH2O
18.0153
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YMDB00900oxygen
7782-44-7
dioxygenO2
31.9988
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YMDB00914ADP
58-64-0
[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acidC10H15N5O10P2
427.2011
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YMDB00948D-ribulose 5-phosphate
4151-19-3
{[(2R,3R)-2,3,5-trihydroxy-4-oxopentyl]oxy}phosphonic acidC5H11O8P
230.1098
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YMDB01028dioxygen
7782-44-7
O2
31.9988
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YMDB163092,5-Diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate 2-[(2,5-diamino-6-oxo-1,6-dihydropyrimidin-4-yl)amino]-5-[(phosphonatooxy)methyl]oxolane-3,4-bis(olate)C9H12N5O8P
349.198
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YMDB163102,5-Diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate 1-[(2,5-diamino-6-oxo-1,6-dihydropyrimidin-4-yl)amino]-5-(phosphonatooxy)pentane-2,3,4-tris(olate)C9H13N5O8P
350.207
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YMDB163115-Amino-2,6-dioxy-4-(5'-phospho-D-ribitylamino)pyrimidine 1-[(5-amino-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino]-5-(phosphonatooxy)pentane-2,3,4-tris(olate)C9H12N4O9P
351.191
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Pathway Proteins

Uniprot ID Gene Name
Locus
Name Type Metabolites
P25353NPP1
YCR026C
Ectonucleotide pyrophosphatase/phosphodiesterase 1Enzyme
P39997NPP2
YEL016C
Ectonucleotide pyrophosphatase/phosphodiesterase 2Enzyme
P35842PHO11
YAR071W
Acid phosphatase PHO11Enzyme
Q03778FMN1
YDR236C
Riboflavin kinaseEnzyme
P00635PHO5
YBR093C
Repressible acid phosphataseEnzyme
P38913FAD1
YDL045C
FAD synthaseEnzyme
Q12362RIB2
YOL066C
Bifunctional protein RIB2Enzyme
P38066RIB1
YBL033C
GTP cyclohydrolase-2Enzyme
P33312RIB7
YBR153W
5-amino-6-(5-phosphoribosylamino)uracil reductaseEnzyme
P50861RIB4
YOL143C
6,7-dimethyl-8-ribityllumazine synthaseEnzyme
P38145RIB5
YBR256C
Riboflavin synthase alpha chainEnzyme
Q99258RIB3
YDR487C
3,4-dihydroxy-2-butanone 4-phosphate synthaseEnzyme
P24031PHO3
YBR092C
Constitutive acid phosphataseEnzyme
P40347LTP1
YPR073C
Low molecular weight phosphotyrosine protein phosphataseEnzyme
P52290DIA3
YDL024C
Probable acid phosphatase DIA3Enzyme
P38693PHO12
YHR215W
Acid phosphatase PHO12Enzyme