Biotin metabolism

SourceIDPathway
KEGG00780 Map00780

Pathway Metabolites

YMDB ID Name
CAS Number
IUPAC Name Formula
Weight
Structure
YMDB00075Dethiobiotin
533-48-2
6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanoic acidC10H18N2O3
214.2615
Thumb
YMDB001027,8-diaminononanoic acid
21738-21-6
7,8-diaminononanoic acidC9H20N2O2
188.2673
Thumb
YMDB00282Biotin
58-85-5
5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acidC10H16N2O3S
244.311
Thumb
YMDB00330L-Lysine
56-87-1
(2S)-2,6-diaminohexanoic acidC6H14N2O2
146.1876
Thumb
YMDB00525pimeloyl-CoA
18907-20-5
7-[(2-{3-[(2R)-3-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-2-hydroxy-3-methylbutanamido]propanamido}ethyl)sulfanyl]-7-oxoheptanoic acidC28H46N7O19P3S
909.687
Thumb
YMDB00602Biotinyl-5'-AMP
4130-20-5
({5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazolidin-4-yl]pentanoyl}oxy)({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy})phosphinic acidC20H28N7O9PS
573.517
Thumb
YMDB009058-Amino-7-oxononanoic acid
4707-58-8
C9H17NO3
187.2362
Thumb
YMDB010187,8-diaminononanoateC16H32O2
256.4241
Thumb
YMDB010528-amino-7-oxononanoateC9H16NO3
186.2282
Thumb

Pathway Proteins

Uniprot ID Gene Name
Locus
Name Type Metabolites
P32451BIO2
YGR286C
Biotin synthase, mitochondrialEnzyme
P53630BIO4
YNR057C
Dethiobiotin synthetaseEnzyme
P48445BPL1
YDL141W
Biotin--protein ligaseEnzyme
P50277BIO3
YNR058W
Adenosylmethionine-8-amino-7-oxononanoate aminotransferaseEnzyme