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Phenylalanine, tyrosine and tryptophan biosynthesis

SourceIDPathway
KEGG00400 Map00400

Pathway Metabolites

YMDB ID Name
CAS Number
IUPAC Name Formula
Weight
Structure
YMDB000317-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid
2627-73-8
(4R,5S,6R)-4,5,6-trihydroxy-2-oxo-7-(phosphonooxy)heptanoic acidC7H13O10P
288.1459
Thumb
YMDB00034L-aspartic 4-semialdehyde
15106-57-7
(2S)-2-amino-4-oxobutanoic acidC4H7NO3
117.1033
Thumb
YMDB00054N-(5-phospho-beta-D-ribosyl)anthranilic acid2-{[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]amino}benzoic acidC12H16NO9P
349.2305
Thumb
YMDB001003-Dehydroquinate
105735-75-9
(1R,3R,4S)-1,3,4-trihydroxy-5-oxocyclohexane-1-carboxylic acidC7H10O6
190.1507
Thumb
YMDB00126L-Tryptophan
73-22-3
(2S)-2-amino-3-(1H-indol-3-yl)propanoic acidC11H12N2O2
204.2252
Thumb
YMDB00148Chorismate
55508-12-8
(3R,4R)-3-[(1-carboxyeth-1-en-1-yl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylic acidC10H10O6
226.1828
Thumb
YMDB001514-Hydroxyphenylpyruvic acid
156-39-8
3-hydroxy-2-oxo-3-phenylpropanoic acidC9H8O4
180.1574
Thumb
YMDB00179(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate[(2R,3S)-2,3-dihydroxy-3-(1H-indol-3-yl)propoxy]phosphonic acidC11H14NO6P
287.2057
Thumb
YMDB00216Shikimic acid
138-59-0
(3R,4S,5R)-3,4,5-trihydroxycyclohex-1-ene-1-carboxylic acidC7H10O5
174.1513
Thumb
YMDB00217N-(5-Phospho-beta-D-ribosyl)anthranilic acid (Duplicate)2-{[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]amino}benzoic acidC12H16NO9P
349.2305
Thumb
YMDB00223D-Erythrose 4-phosphate
585-18-2
[(2R,3R)-2,3-dihydroxy-4-oxobutoxy]phosphonic acidC4H9O7P
200.0838
Thumb
YMDB002511-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate
5962-18-5
2-{[(3R,4R)-3,4-dihydroxy-2-oxo-5-(phosphonooxy)pentyl]amino}benzoic acidC12H16NO9P
349.2305
Thumb
YMDB00276Phosphoenolpyruvic acid
138-08-9
2-(phosphonooxy)prop-2-enoic acidC3H5O6P
168.042
Thumb
YMDB002782-Aminobenzoic acid
118-92-3
2-aminobenzoic acidC7H7NO2
137.136
Thumb
YMDB00304L-Phenylalanine
63-91-2
(2S)-2-amino-3-phenylpropanoic acidC9H11NO2
165.1891
Thumb
YMDB00324Prephenate
126-49-8
1-(2-carboxy-2-oxoethyl)-4-hydroxycyclohexa-2,5-diene-1-carboxylic acidC10H10O6
226.1828
Thumb
YMDB003323-Phosphoshikimic acid
63959-45-5
(3R,4S,5R)-4,5-dihydroxy-3-(phosphonooxy)cyclohex-1-ene-1-carboxylic acidC7H11O8P
254.1312
Thumb
YMDB003615-O-(1-carboxyvinyl)-3-phosphoshikimic acid
89771-75-5
(3R,4S,5R)-5-[(1-carboxyeth-1-en-1-yl)oxy]-4-hydroxy-3-(phosphonooxy)cyclohex-1-ene-1-carboxylic acidC10H13O10P
324.178
Thumb
YMDB00364L-Tyrosine
60-18-4
(2S)-2-amino-3-(4-hydroxyphenyl)propanoic acidC9H11NO3
181.1885
Thumb
YMDB003903-Dehydroshikimic acid
27655-56-7
(4S,5R)-4,5-dihydroxy-3-oxocyclohex-1-ene-1-carboxylic acidC7H8O5
172.1354
Thumb
YMDB00402Phosphoribosyl pyrophosphate
7540-64-9
[({[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]oxy}(hydroxy)phosphoryl)oxy]phosphonic acidC5H13O14P3
390.0696
Thumb
YMDB004583-Dehydroshikimate
27655-56-7
(4S,5R)-4,5-dihydroxy-3-oxocyclohex-1-ene-1-carboxylic acidC7H7O5
171.1275
Thumb
YMDB007091-C-(indol-3-yl)glycerol 3-phosphate[2,3-dihydroxy-3-(1H-indol-3-yl)propoxy]phosphonic acidC11H14NO6P
287.2057
Thumb
YMDB00786keto-phenylpyruvic acid
156-06-9
2-oxo-3-phenylpropanoic acidC9H8O3
164.158
Thumb
YMDB00958(4-hydroxyphenyl)pyruvic acid
156-39-8
3-(4-hydroxyphenyl)-2-oxopropanoic acidC9H8O4
180.1574
Thumb
YMDB01022L-aspartate 4-semialdehyde
15106-57-7
(2S)-2-amino-4-oxobutanoateC4H6NO3
116.0953
Thumb
YMDB01050phosphoenolpyruvate
138-08-9
2-(phosphonooxy)prop-2-enoateC3H4O6P
167.034
Thumb
YMDB01055Shikimate
138-59-0
(3R,4S,5R)-3,4,5-trihydroxycyclohex-1-ene-1-carboxylateC7H9O5
173.1434
Thumb
YMDB01073keto-phenylpyruvate
156-06-9
2-oxo-3-phenylpropanoateC9H7O3
163.1501
Thumb
YMDB010843-(4-hydroxyphenyl)pyruvate
156-39-8
3-(4-hydroxyphenyl)-2-oxopropanoateC9H7O4
179.1495
Thumb
YMDB01092Anthranilate
118-92-3
2-aminobenzoateC7H6NO2
136.128
Thumb
YMDB01321Protocatechuic acid
99-50-3
3,4-dihydroxybenzoic acidC7H6O4
154.1201
Thumb

Pathway Proteins

Uniprot ID Gene Name
Locus
Name Type Metabolites
P00937TRP3
YKL211C
Anthranilate synthase component 2Enzyme
P00899TRP2
YER090W
Anthranilate synthase component 1Enzyme
P08566ARO1
YDR127W
Pentafunctional AROM polypeptideEnzyme
P32449ARO4
YBR249C
Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibitedEnzyme
P14843ARO3
YDR035W
Phospho-2-dehydro-3-deoxyheptonate aldolase, phenylalanine-inhibitedEnzyme
P07285TRP4
YDR354W
Anthranilate phosphoribosyltransferaseEnzyme
P07172HIS5
YIL116W
Histidinol-phosphate aminotransferaseEnzyme
P00931TRP5
YGL026C
Tryptophan synthaseEnzyme
P38840ARO9
YHR137W
Aromatic amino acid aminotransferase 2Enzyme
P53090ARO8
YGL202W
Aromatic amino acid aminotransferase 1Enzyme
P20049TYR1
YBR166C
Prephenate dehydrogenase [NADP+]Enzyme
P28777ARO2
YGL148W
Chorismate synthaseEnzyme
P32178ARO7
YPR060C
Chorismate mutaseEnzyme
Q01802AAT1
YKL106W
Aspartate aminotransferase, mitochondrialEnzyme
P23542AAT2
YLR027C
Aspartate aminotransferase, cytoplasmicEnzyme
P00912TRP1
YDR007W
N-(5'-phosphoribosyl)anthranilate isomeraseEnzyme
P32452PHA2
YNL316C
Putative prephenate dehydrataseEnzyme