Glyoxylate and dicarboxylate metabolism

SourceIDPathway
KEGG00630 Map00630

Pathway Metabolites

YMDB ID Name
CAS Number
IUPAC Name Formula
Weight
Structure
YMDB00026Isocitric acid
320-77-4
1-hydroxypropane-1,2,3-tricarboxylic acidC6H8O7
192.1235
Thumb
YMDB00033Glyoxylic acid
298-12-4
2-oxoacetic acidC2H2O3
74.0355
Thumb
YMDB00086Citric acid
77-92-9
2-hydroxypropane-1,2,3-tricarboxylic acidC6H8O7
192.1235
Thumb
YMDB00153Oxoglutaric acid
328-50-7
2-oxopentanedioic acidC5H6O5
146.0981
Thumb
YMDB00175Pyruvic acid
127-17-3
2-oxopropanoic acidC3H4O3
88.0621
Thumb
YMDB00235Oxalacetic acid
328-42-7
2-oxobutanedioic acidC4H4O5
132.0716
Thumb
YMDB00280(S)-Malic acid
97-67-6
(2S)-2-hydroxybutanedioic acidC4H6O5
134.0874
Thumb
YMDB00312Acetyl-CoA
72-89-9
{[(2R,3S,4R,5R)-2-({[({[(3R)-3-[(2-{[2-(acetylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-5-(6-amino-9H-purin-9-yl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acidC23H38N7O17P3S
809.571
Thumb
YMDB00338Succinic acid
110-15-6
butanedioic acidC4H6O4
118.088
Thumb
YMDB00343Glycolaldehyde
141-46-8
2-hydroxyacetaldehydeC2H4O2
60.052
Thumb
YMDB00385Formic acid
64-18-6
formic acidCH2O2
46.0254
Thumb
YMDB00446propionyl-CoA
317-66-8
{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl-3-[(2-{[2-(propanoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]propoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan-3-yl]oxy}phosphonic acidC24H40N7O17P3S
823.597
Thumb
YMDB00514Succinyl-CoA
604-98-8
4-[(2-{3-[(2R)-3-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-2-hydroxy-3-methylbutanamido]propanamido}ethyl)sulfanyl]-4-oxobutanoic acidC25H40N7O19P3S
867.607
Thumb
YMDB00529acetoacetyl-CoA
1420-36-6
{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl-3-{[2-({2-[(3-oxobutanoyl)sulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}propoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan-3-yl]oxy}phosphonic acidC25H40N7O18P3S
851.607
Thumb
YMDB00630cis-aconitic acid
585-84-2
(1Z)-prop-1-ene-1,2,3-tricarboxylic acidC6H6O6
174.1082
Thumb
YMDB007224-hydroxy-2-oxoglutaric acid
1187-99-1
2-hydroxy-4-oxopentanedioic acidC5H6O6
162.0975
Thumb
YMDB007563-phospho-D-glyceric acid
820-11-1
(2R)-2-hydroxy-3-(phosphonooxy)propanoic acidC3H7O7P
186.0572
Thumb
YMDB00807glycolic acid
79-14-1
2-hydroxyacetic acidC2H4O3
76.0514
Thumb
YMDB00858Phosphoglycolic acid
13147-57-4
2-(phosphonooxy)acetic acidC2H5O6P
156.0313
Thumb
YMDB00912Carbon dioxide
124-38-9
methanedioneCO2
44.0095
Thumb
YMDB01025formate
64-18-6
CHO2
45.0174
Thumb
YMDB01033Glyoxylate
298-12-4
C2HO3
73.0275
Thumb
YMDB01053pyruvate
127-17-3
C3H3O3
87.0541
Thumb

Pathway Proteins

Uniprot ID Gene Name
Locus
Name Type Metabolites
P19414ACO1
YLR304C
Aconitate hydratase, mitochondrialEnzyme
P39533ACO2
YJL200C
Probable aconitate hydratase 2Enzyme
P28240ICL1
YER065C
Isocitrate lyaseEnzyme
P30952MLS1
YNL117W
Malate synthase 1, glyoxysomalEnzyme
P21826DAL7
YIR031C
Malate synthase 2, glyoxysomalEnzyme
P43635CIT3
YPR001W
Citrate synthase 3Enzyme
P08679CIT2
YCR005C
Citrate synthase, peroxisomalEnzyme
P00890CIT1
YNR001C
Citrate synthase, mitochondrialEnzyme
P09440MIS1
YBR084W
C-1-tetrahydrofolate synthase, mitochondrialEnzyme
P07245ADE3
YGR204W
C-1-tetrahydrofolate synthase, cytoplasmicEnzyme
P22133MDH2
YOL126C
Malate dehydrogenase, cytoplasmicEnzyme
Q08911FDH1
YOR388C
Formate dehydrogenase 1Enzyme
P32419MDH3
YDL078C
Malate dehydrogenase, peroxisomalEnzyme
P0CF35FDH2
YPL275W
Putative formate dehydrogenase 2Enzyme
Q04066BNA7
YDR428C
Probable kynurenine formamidaseEnzyme
P17505MDH1
Malate dehydrogenase, mitochondrialEnzyme