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Arginine and proline metabolism

SourceIDPathway
KEGG00330 Map00330

Pathway Metabolites

YMDB ID Name
CAS Number
IUPAC Name Formula
Weight
Structure
YMDB00002L-Glutamine
56-85-9
(2S)-2-amino-4-carbamoylbutanoic acidC5H10N2O3
146.1445
Thumb
YMDB00003Urea
57-13-6
ureaCH4N2O
60.0553
Thumb
YMDB00028N-Acetylornithine
6205-08-9
(2S)-5-amino-2-acetamidopentanoic acidC7H14N2O3
174.1977
Thumb
YMDB00033Glyoxylic acid
298-12-4
2-oxoacetic acidC2H2O3
74.0355
Thumb
YMDB00034L-aspartic 4-semialdehyde
15106-57-7
(2S)-2-amino-4-oxobutanoic acidC4H7NO3
117.1033
Thumb
YMDB000421,3-Diaminopropane
109-76-2
propane-1,3-diamineC3H10N2
74.1249
Thumb
YMDB00047N-Acetyl-L-glutamyl 5-phosphate
15383-57-0
(2S)-2-acetamido-5-oxo-5-(phosphonooxy)pentanoic acidC7H12NO8P
269.1458
Thumb
YMDB00052Argininosuccinic acid
2387-71-5
(2S)-2-{3-[(4S)-4-amino-4-carboxybutyl]carbamimidamido}butanedioic acidC10H18N4O6
290.2731
Thumb
YMDB00060Citrulline
372-75-8
(2S)-2-amino-5-(carbamoylamino)pentanoic acidC6H13N3O3
175.1857
Thumb
YMDB00066N-acetyl-L-glutamic acid
1188-37-0
(2S)-2-acetamidopentanedioic acidC7H11NO5
189.1659
Thumb
YMDB00082Carbamoylphosphate
590-55-6
(carbamoyloxy)phosphonic acidCH4NO5P
141.0199
Thumb
YMDB00091Ammonia
7664-41-7
ammoniaH3N
17.0305
Thumb
YMDB00101Fumaric acid
110-17-8
(2E)-but-2-enedioic acidC4H4O4
116.0722
Thumb
YMDB00124urea-1-carboxylic acid
625-78-5
carbamoylcarbamic acidC2H4N2O3
104.0648
Thumb
YMDB00130S-Adenosylmethioninamine
22365-13-5
{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(3-aminopropyl)methylsulfaniumC14H23N6O3S
355.436
Thumb
YMDB00132Putrescine
110-60-1
butane-1,4-diamineC4H12N2
88.1515
Thumb
YMDB00175Pyruvic acid
127-17-3
2-oxopropanoic acidC3H4O3
88.0621
Thumb
YMDB002094-acetamidobutanalN-(4-oxobutyl)acetamideC6H11NO2
129.157
Thumb
YMDB00231Spermine
71-44-3
(3-aminopropyl)({4-[(3-aminopropyl)amino]butyl})amineC10H26N4
202.3402
Thumb
YMDB00232Spermidine
124-20-9
(4-aminobutyl)(3-aminopropyl)amineC7H19N3
145.2459
Thumb
YMDB00233L-Glutamic acid 5-phosphate
13254-53-0
(2S)-2-amino-5-oxo-5-(phosphonooxy)pentanoic acidC5H10NO7P
227.1092
Thumb
YMDB002431-Pyrroline-5-carboxylic acid
2906-39-0
3,4-dihydro-2H-pyrrole-2-carboxylic acidC5H7NO2
113.1146
Thumb
YMDB00255N-Acetyl-L-glutamate 5-semialdehyde
13074-21-0
(2S)-2-acetamido-5-oxopentanoic acidC7H11NO4
173.1665
Thumb
YMDB00271L-Glutamic acid
56-86-0
(2S)-2-aminopentanedioic acidC5H9NO4
147.1293
Thumb
YMDB00297S-Adenosylmethionine
29908-03-0
[(3S)-3-amino-3-carboxypropyl]({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl})methylsulfaniumC15H23N6O5S
399.445
Thumb
YMDB00335gamma-Aminobutyric acid
56-12-2
4-aminobutanoic acidC4H9NO2
103.1198
Thumb
YMDB00378L-Proline
147-85-3
(2S)-pyrrolidine-2-carboxylic acidC5H9NO2
115.1305
Thumb
YMDB004191-Pyrroline-5-carboxylate3,4-dihydro-2H-pyrrole-2-carboxylic acidC5H6NO2
112.1066
Thumb
YMDB00438S-Adenosyl-L-methionine
29908-03-0
[(3S)-3-amino-3-carboxypropyl]({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl})methylsulfaniumC15H23N6O5S
399.445
Thumb
YMDB004894-Acetamidobutanoic acid
3025-96-5
4-acetamidobutanoic acidC6H11NO3
145.1564
Thumb
YMDB004974-Coumaroyl-CoA
119785-99-8
{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-3-({2-[(2-{[3-(4-hydroxyphenyl)prop-2-enoyl]sulfanyl}ethyl)carbamoyl]ethyl}carbamoyl)-2,2-dimethylpropoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan-3-yl]oxy}phosphonic acidC30H42N7O18P3S
913.677
Thumb
YMDB005362-Acetamido-5-oxopentanoic acid(2S)-2-acetamido-5-oxopentanoic acidC7H11NO4
173.1665
Thumb
YMDB005854-guanidinobutanoic acid
463-00-3
4-[(diaminomethylidene)amino]butanoic acidC5H11N3O2
145.1597
Thumb
YMDB005864-guanidinobutanamide4-carbamimidamidobutanamideC5H12N4O
144.175
Thumb
YMDB005874-aminobutanal
4390-05-0
4-aminobutanalC4H9NO
87.1204
Thumb
YMDB00592L-Arginine
74-79-3
(2S)-2-amino-5-carbamimidamidopentanoic acidC6H14N4O2
174.201
Thumb
YMDB00593(N(omega)-L-arginino)succinic acid
2387-71-5
2-{3-[(4S)-4-amino-4-carboxybutyl]carbamimidamido}butanedioic acidC10H18N4O6
290.2731
Thumb
YMDB00720L-4-hydroxyglutamic semialdehyde(2S,4R)-2-amino-4-hydroxy-5-oxopentanoic acidC5H9NO4
147.1293
Thumb
YMDB00723trans-4-hydroxy-L-proline
51-35-4
(2S,4R)-4-hydroxypyrrolidine-2-carboxylic acidC5H9NO3
131.1299
Thumb
YMDB00738N-Acetylputrescine
18233-70-0
N-(4-aminobutyl)acetamideC6H14N2O
130.1882
Thumb
YMDB00896L-Aspartic acid
56-84-8
(2S)-2-aminobutanedioic acidC4H7NO4
133.1027
Thumb
YMDB00903D-Proline
344-25-2
(2R)-pyrrolidine-2-carboxylic acidC5H9NO2
115.1305
Thumb
YMDB00912Carbon dioxide
124-38-9
methanedioneCO2
44.0095
Thumb
YMDB00918l-Glutamic-gamma-semialdehyde
496-92-4
(2S)-2-amino-5-oxopentanoic acidC5H9NO3
131.1299
Thumb
YMDB00980(5-Deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium
22365-13-5
{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(3-aminopropyl)methylsulfaniumC14H23N6O3S
355.436
Thumb
YMDB00982no
10102-43-9
nitrosoNO
30.0061
Thumb
YMDB01022L-aspartate 4-semialdehyde
15106-57-7
(2S)-2-amino-4-oxobutanoateC4H6NO3
116.0953
Thumb
YMDB010264-acetamidobutanoate
3025-96-5
4-acetamidobutanoateC6H10NO3
144.1485
Thumb
YMDB01033Glyoxylate
298-12-4
2-oxoacetateC2HO3
73.0275
Thumb
YMDB01038fumarate(2-)
110-17-8
C4H2O4
114.0563
Thumb
YMDB01053pyruvate
127-17-3
C3H3O3
87.0541
Thumb
YMDB01059gamma-Aminobutyrate
56-12-2
4-aminobutanoateC4H8NO2
102.1118
Thumb
YMDB01074N-acetyl-L-glutamate(2-)
1188-37-0
(2S)-2-acetamidopentanedioateC7H9NO5
187.1501
Thumb

Pathway Proteins

Uniprot ID Gene Name
Locus
Name Type Metabolites
P32288GLN1
YPR035W
Glutamine synthetaseEnzyme
P32528DUR1
YBR208C
Urea amidolyaseEnzyme
P00812CAR1
YPL111W
ArginaseEnzyme
P46367ALD4
YOR374W
Potassium-activated aldehyde dehydrogenase, mitochondrialEnzyme
P54115ALD6
YPL061W
Magnesium-activated aldehyde dehydrogenase, cytosolicEnzyme
P18544ARG8
YOL140W
Acetylornithine aminotransferase, mitochondrialEnzyme
Q04728ARG7
YMR062C
Arginine biosynthesis bifunctional protein ArgJ, mitochondrialEnzyme
P40360ARG2
YJL071W
Amino-acid acetyltransferase, mitochondrialEnzyme
Q01217ARG5
YER069W
Protein ARG5,6, mitochondrialEnzyme
P22768ARG1
YOL058W
Argininosuccinate synthaseEnzyme
P04076ARG4
YHR018C
Argininosuccinate lyaseEnzyme
P05150ARG3
YJL088W
Ornithine carbamoyltransferaseEnzyme
Q12178FCY1
YPR062W
Cytosine deaminaseEnzyme
P33327GDH2
YDL215C
NAD-specific glutamate dehydrogenaseEnzyme
P39708GDH3
YAL062W
NADP-specific glutamate dehydrogenase 2Enzyme
P07262GDH1
YOR375C
NADP-specific glutamate dehydrogenase 1Enzyme
P22580AMD2
YDR242W
Probable amidaseEnzyme
P32264PRO1
YDR300C
Glutamate 5-kinaseEnzyme
P22281ALD1
Aldehyde dehydrogenase 1, mitochondrialEnzyme
Q12455SPE4
YLR146C
Spermine synthaseEnzyme
Q12074SPE3
YPR069C
Spermidine synthaseEnzyme
P21182SPE2
YOL052C
S-adenosylmethionine decarboxylase proenzymeEnzyme
P08432SPE1
YKL184W
Ornithine decarboxylaseEnzyme
P07275PUT2
YHR037W
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrialEnzyme
P09368PUT1
YLR142W
Proline dehydrogenase, mitochondrialEnzyme
P32263PRO3
YER023W
Pyrroline-5-carboxylate reductaseEnzyme
P54885PRO2
YOR323C
Gamma-glutamyl phosphate reductaseEnzyme
Q01802AAT1
YKL106W
Aspartate aminotransferase, mitochondrialEnzyme
P23542AAT2
YLR027C
Aspartate aminotransferase, cytoplasmicEnzyme
P07991CAR2
YLR438W
Ornithine aminotransferaseEnzyme