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Thiamine metabolism

SourceIDPathway
KEGG00730 Map00730

Pathway Metabolites

YMDB ID Name
CAS Number
IUPAC Name Formula
Weight
Structure
YMDB00016Glycine
56-40-6
2-aminoacetic acidC2H5NO2
75.0666
Thumb
YMDB00046L-Cysteine
52-90-4
(2R)-2-amino-3-sulfanylpropanoic acidC3H7NO2S
121.158
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YMDB000655-Aminoimidazole ribonucleotide
25635-88-5
{[(2R,3S,4R,5R)-5-(5-amino-1H-imidazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acidC8H14N3O7P
295.1864
Thumb
YMDB00115D-Glyceraldehyde 3-phosphate
142-10-9
(2-hydroxy-3-oxopropoxy)phosphonic acidC3H7O6P
170.0578
Thumb
YMDB001174-amino-2-methyl-5-diphosphomethylpyrimidine({hydroxy[(6-imino-2-methyl-1,6-dihydropyrimidin-5-yl)methoxy]phosphoryl}oxy)phosphonic acidC6H11N3O7P2
299.115
Thumb
YMDB001184-amino-5-hydroxymethyl-2-methylpyrimidine
73-67-6
(4-amino-2-methylpyrimidin-5-yl)methanolC6H9N3O
139.1552
Thumb
YMDB001284-amino-2-methyl-5-phosphomethylpyrimidine[(6-imino-2-methyl-1,6-dihydropyrimidin-5-yl)methoxy]phosphonic acidC6H10N3O4P
219.1351
Thumb
YMDB00164Thiamine monophosphate
495-23-8
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-[2-(hydrogen phosphonatooxy)ethyl]-4-methyl-1,3-thiazol-3-iumC12H17N4O4PS
344.327
Thumb
YMDB00175Pyruvic acid
127-17-3
2-oxopropanoic acidC3H4O3
88.0621
Thumb
YMDB00220Thiamine
59-43-8
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-iumC12H17N4OS
265.355
Thumb
YMDB003194-Methyl-5-(2-phosphonooxyethyl)thiazole[2-(4-methyl-1,3-thiazol-5-yl)ethoxy]phosphonic acidC6H10NO4PS
223.187
Thumb
YMDB00364L-Tyrosine
60-18-4
(2S)-2-amino-3-(4-hydroxyphenyl)propanoic acidC9H11NO3
181.1885
Thumb
YMDB00381Thiamine pyrophosphate
154-87-0
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-iumC12H19N4O7P2S
425.314
Thumb
YMDB004925-Amino-1-(5-phospho-D-ribosyl)imidazole
25635-88-5
{[(2R,3S,4R)-5-(5-amino-1H-imidazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acidC8H14N3O7P
295.1864
Thumb
YMDB007065-(2-Hydroxyethyl)-4-methylthiazole
137-00-8
2-(4-methyl-1,3-thiazol-5-yl)ethan-1-olC6H9NOS
143.207
Thumb
YMDB00774Thiamine(1+) monophosphate
532-40-1
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-5-[2-(phosphonooxy)ethyl]-1,3-thiazol-3-iumC12H18N4O4PS
345.334
Thumb
YMDB00775Thiamine triphosphate3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[hydroxy({[hydroxy(phosphonooxy)phosphoryl]oxy})phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-iumC12H20N4O10P3S
505.294
Thumb
YMDB00793Toxopyrimidine
73-67-6
(4-amino-2-methylpyrimidin-5-yl)methanolC6H9N3O
139.1552
Thumb
YMDB01053pyruvate
127-17-3
C3H3O3
87.0541
Thumb

Pathway Proteins

Uniprot ID Gene Name
Locus
Name Type Metabolites
P25374NFS1
YCL017C
Cysteine desulfurase, mitochondrialEnzyme
P35202THI80
YOR143C
Thiamine pyrophosphokinaseEnzyme
Q08975THI21
YPL258C
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21Enzyme
Q08224THI20
YOL055C
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20Enzyme
P41835THI6
YPL214C
Thiamine biosynthetic bifunctional enzymeEnzyme