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Glycerophospholipid metabolism

SourceIDPathway
PathWhizPW002493 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG00564 Map00564

Pathway Metabolites

YMDB ID Name
CAS Number
IUPAC Name Formula
Weight
Structure
YMDB00009Ethanolamine
141-43-5
2-aminoethan-1-olC2H7NO
61.0831
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YMDB00022Acetaldehyde
75-07-0
acetaldehydeC2H4O
44.0526
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YMDB00045Coenzyme A
85-61-0
{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl-3-({2-[(2-sulfanylethyl)carbamoyl]ethyl}carbamoyl)propoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan-3-yl]oxy}phosphonic acidC21H36N7O16P3S
767.534
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YMDB00064CDP
63-38-7
[({[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acidC9H15N3O11P2
403.1764
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YMDB00069Palmitic acid
57-10-3
hexadecanoic acidC16H32O2
256.4241
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YMDB00073Glycerol 3-phosphate
17989-41-2
[(2R)-2,3-dihydroxypropoxy]phosphonic acidC3H9O6P
172.0737
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YMDB00090Citicoline
987-78-0
{2-[({[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl phosphonato)oxy]ethyl}trimethylazaniumC14H26N4O11P2
488.324
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YMDB00109Adenosine triphosphate
56-65-5
({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acidC10H16N5O13P3
507.181
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YMDB00110NAD
53-84-9
1-[(2R,3R,4S,5R)-5-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1λ⁵-pyridin-1-yliumC21H28N7O14P2
664.433
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YMDB00125O-Phosphoethanolamine
1071-23-4
(2-aminoethoxy)phosphonic acidC2H8NO4P
141.063
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YMDB00143NADH
58-68-4
[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy})phosphinic acidC21H29N7O14P2
665.441
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YMDB001871-palmitoylglycerone 3-phosphate[3-(hexadecanoyloxy)-2-oxopropoxy]phosphonic acidC19H37O7P
408.4666
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YMDB00191Phosphorylcholine
3616-04-4
[2-(trimethylazaniumyl)ethoxy]phosphonic acidC5H15NO4P
184.1507
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YMDB00219Pyrophosphate
14000-31-8
(phosphonooxy)phosphonic acidH4O7P2
177.9751
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YMDB00227Choline
62-49-7
(2-hydroxyethyl)trimethylazaniumC5H14NO
104.1708
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YMDB002301-Phosphatidyl-D-myo-inositol[2,3-bis(formyloxy)propoxy]({[(2R,3S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy})phosphinic acidC11H19O13P
390.2345
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YMDB00259LPA(16:0/0:0)[3-(hexadecanoyloxy)-2-hydroxypropoxy]phosphonic acidC19H39O7P
410.4825
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YMDB00275Dihydroxyacetone phosphate acyl ester[3-(formyloxy)-2-oxopropoxy]phosphonic acidC4H7O7P
198.0679
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YMDB00279Cytidine triphosphate
65-47-4
({[({[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acidC9H16N3O14P3
483.1563
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YMDB00301Palmityl-CoA
1763-10-6
{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-[({[({3-[(2-{[2-(hexadecanoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-4-hydroxyoxolan-3-yl]oxy}phosphonic acidC37H66N7O17P3S
1005.943
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YMDB00309Glycerophosphocholine
28319-77-9
(2-{[(2S)-2,3-dihydroxypropyl phosphonato]oxy}ethyl)trimethylazaniumC8H20NO6P
257.2213
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YMDB00322Dihydroxyacetone phosphate
57-04-5
(3-hydroxy-2-oxopropoxy)phosphonic acidC3H7O6P
170.0578
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YMDB00389CDP-Ethanolamine
3036-18-8
[({[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](2-aminoethoxy)phosphinic acidC11H20N4O11P2
446.2442
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YMDB00406Cytidine monophosphate
63-37-6
{[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acidC9H14N3O8P
323.1965
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YMDB00426NADPH
53-57-6
{[(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-[({[({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-4-hydroxyoxolan-3-yl]oxy}phosphonic acidC21H30N7O17P3
745.4209
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YMDB00427NADP
53-59-8
1-[(2R,3R,4S,5R)-5-[({[({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1λ⁵-pyridin-1-yliumC21H29N7O17P3
744.4129
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YMDB00469hexadec-2-enoyl-CoA
4460-95-1
{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-({[({[(3R)-3-[(2-{[2-(hexadec-2-enoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acidC37H64N7O17P3S
1003.927
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YMDB00527palmitoyl-CoA
1763-10-6
{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-({[({[(3R)-3-[(2-{[2-(hexadecanoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acidC37H66N7O17P3S
1005.943
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YMDB00694sn-Glycero-3-phosphocholine
563-24-6
[(2R)-2,3-dihydroxypropoxy][2-(trimethylazaniumyl)ethoxy]phosphinic acidC8H21NO6P
258.2292
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YMDB00785cerotic acid
57-10-3
hexacosanoic acidC26H52O2
396.6899
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YMDB00818lysophosphatidic acid
22002-87-5
C21H41O7P
436.5198
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YMDB00862hydron
12408-02-5
hydronH
1.00794
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YMDB00890water
7732-18-5
waterH2O
18.0153
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YMDB00907phosphate
14265-44-2
phosphoric acidO4P
94.9714
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YMDB00914ADP
58-64-0
[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acidC10H15N5O10P2
427.2011
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YMDB00988sn-glycerol 3-phosphate
17989-41-2
[(2R)-2,3-dihydroxypropoxy]phosphonic acidC3H9O6P
172.0737
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YMDB00989glycerol 1-phosphate
17989-41-2
(2,3-dihydroxypropoxy)phosphonic acidC3H9O6P
172.0737
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YMDB01127DG(16:0/16:0/0:0)
30334-71-5
(2S)-1-(hexadecanoyloxy)-3-hydroxypropan-2-yl hexadecanoateC35H68O5
568.9114
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YMDB01160PA(16:0/0:0)[3-(hexadecanoyloxy)-2-hydroxypropoxy]phosphonic acidC19H39O7P
410.4825
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YMDB01161PA(16:0/16:0)
169051-60-9
[(2R)-2,3-bis(hexadecanoyloxy)propoxy]phosphonic acidC35H69O8P
648.903
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YMDB01163PA(16:0/18:1(9Z))[(2R)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propoxy]phosphonic acidC37H71O8P
674.941
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YMDB01169PA(18:1(9Z)/18:1(9Z))
14268-17-8
[(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propoxy]phosphonic acidC39H73O8P
700.979
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YMDB01170PA(18:1(9Z)/0:0)
22002-87-5
[(2R)-2-hydroxy-3-[(9Z)-octadec-9-enoyloxy]propoxy]phosphonic acidC21H41O7P
436.5198
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YMDB01175PC(14:0/0:0)(2-{[(2R)-2-hydroxy-3-(tetradecanoyloxy)propyl phosphonato]oxy}ethyl)trimethylazaniumC22H46NO7P
467.5769
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YMDB01176PC(14:0/16:0)
8002-43-5
(2-{[(2R)-2-(hexadecanoyloxy)-3-(tetradecanoyloxy)propyl phosphonato]oxy}ethyl)trimethylazaniumC38H76NO8P
705.9857
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YMDB01177PC(14:0/16:1(9Z))
8002-43-5
(2-{[(2R)-2-[(9Z)-hexadec-9-enoyloxy]-3-(tetradecanoyloxy)propyl phosphonato]oxy}ethyl)trimethylazaniumC38H74NO8P
703.9698
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YMDB01178PC(14:1(9Z)/16:1(9Z))
8002-43-5
(2-{[(2R)-2-[(9Z)-hexadec-9-enoyloxy]-3-[(9Z)-tetradec-9-enoyloxy]propyl phosphonato]oxy}ethyl)trimethylazaniumC38H72NO8P
701.9539
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YMDB01179PC(16:0/0:0)(2-{[(2R)-3-(hexadecanoyloxy)-2-hydroxypropyl phosphonato]oxy}ethyl)trimethylazaniumC24H50NO7P
495.6301
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YMDB01180PC(16:0/16:0)
63-89-8
(2-{[(2R)-2,3-bis(hexadecanoyloxy)propyl phosphono]oxy}ethyl)trimethylazaniumC40H80NO8P
734.0389
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YMDB01181PC(16:0/16:1(9Z))
8002-43-5
(2-{[(2R)-2-[(9Z)-hexadec-9-enoyloxy]-3-(hexadecanoyloxy)propyl phosphonato]oxy}ethyl)trimethylazaniumC40H78NO8P
732.023
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YMDB01182PC(16:0/18:0)
8002-43-5
(2-{[(2R)-3-(hexadecanoyloxy)-2-(octadecanoyloxy)propyl phosphonato]oxy}ethyl)trimethylazaniumC42H84NO8P
762.092
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YMDB01183PC(16:0/18:1(9Z))
8002-43-5
(2-{[(2R)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl phosphonato]oxy}ethyl)trimethylazaniumC42H82NO8P
760.0761
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YMDB01185PC(16:1(9Z)/16:1(9Z))
8002-43-5
(2-{[(2R)-2,3-bis[(9Z)-hexadec-9-enoyloxy]propyl phosphonato]oxy}ethyl)trimethylazaniumC40H76NO8P
730.0071
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YMDB01186PC(16:1(9Z)/18:1(9Z))
8002-43-5
(2-{[(2R)-3-[(9Z)-hexadec-9-enoyloxy]-2-[(9Z)-octadec-9-enoyloxy]propyl phosphonato]oxy}ethyl)trimethylazaniumC42H80NO8P
758.0603
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YMDB01187PC(18:0/0:0)(2-{[(2R)-2-hydroxy-3-(octadecanoyloxy)propyl phosphonato]oxy}ethyl)trimethylazaniumC26H54NO7P
523.6832
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YMDB01188PC(18:0/18:0)
8002-43-5
(2-{[(2R)-2,3-bis(octadecanoyloxy)propyl phosphonato]oxy}ethyl)trimethylazaniumC44H88NO8P
790.1452
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YMDB01189PC(18:0/18:1(9Z))
8002-43-5
trimethyl(2-{[(2R)-2-[(9Z)-octadec-9-enoyloxy]-3-(octadecanoyloxy)propyl phosphonato]oxy}ethyl)azaniumC44H86NO8P
788.1293
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YMDB01190PC(18:1(9Z)/0:0)
3542-29-8
(2-{[(2R)-2-hydroxy-3-[(9Z)-octadec-9-enoyloxy]propyl phosphonato]oxy}ethyl)trimethylazaniumC26H52NO7P
521.6673
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YMDB01191PC(18:1(9Z)/18:1(9Z))
68737-67-7
(2-{[(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl phosphonato]oxy}ethyl)trimethylazaniumC44H84NO8P
786.1134
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YMDB01195PE(14:0/16:1(9Z))(2-aminoethoxy)[(2R)-2-[(9Z)-hexadec-9-enoyloxy]-3-(tetradecanoyloxy)propoxy]phosphinic acidC35H68NO8P
661.902
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YMDB01196PE(14:1(9Z)/16:0)(2-aminoethoxy)[(2R)-2-(hexadecanoyloxy)-3-[(9Z)-tetradec-9-enoyloxy]propoxy]phosphinic acidC35H68NO8P
661.8901
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YMDB01198PE(16:0/16:0)
5681-36-7
(2-aminoethoxy)[(2R)-2,3-bis(hexadecanoyloxy)propoxy]phosphinic acidC37H74NO8P
691.972
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YMDB01199PE(16:0/16:1(9Z))(2-aminoethoxy)[(2R)-2-[(9Z)-hexadec-9-enoyloxy]-3-(hexadecanoyloxy)propoxy]phosphinic acidC37H72NO8P
689.956
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YMDB01200PE(16:0/18:1(9Z))
26662-94-2
(2-aminoethoxy)[(2R)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propoxy]phosphinic acidC39H76NO8P
718.01
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YMDB01202PE(16:1(9Z)/16:1(9Z))(2-aminoethoxy)[(2R)-2,3-bis[(9Z)-hexadec-9-enoyloxy]propoxy]phosphinic acidC37H70NO8P
687.94
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YMDB01203PE(16:1(9Z)/18:1(9Z))(2-aminoethoxy)[(2R)-3-[(9Z)-hexadec-9-enoyloxy]-2-[(9Z)-octadec-9-enoyloxy]propoxy]phosphinic acidC39H74NO8P
715.994
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YMDB01205PE(18:0/16:1(9Z))(2-aminoethoxy)[(2R)-2-[(9Z)-hexadec-9-enoyloxy]-3-(octadecanoyloxy)propoxy]phosphinic acidC39H76NO8P
717.9964
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YMDB01206PE(18:0/18:1(9Z))(2-aminoethoxy)[(2R)-2-[(9Z)-octadec-9-enoyloxy]-3-(octadecanoyloxy)propoxy]phosphinic acidC41H80NO8P
746.064
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YMDB01208PE(18:1(9Z)/18:1(9Z))
2462-63-7
(2-aminoethoxy)[(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propoxy]phosphinic acidC41H78NO8P
744.048
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YMDB01251PS(16:0/16:0)
3036-82-6
(2S)-2-amino-3-({[(2R)-2,3-bis(hexadecanoyloxy)propoxy](hydroxy)phosphoryl}oxy)propanoic acidC38H74NO10P
735.981
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YMDB01257PS(18:0/18:1(9Z))(2S)-2-amino-3-({hydroxy[(2R)-2-[(9Z)-octadec-9-enoyloxy]-3-(octadecanoyloxy)propoxy]phosphoryl}oxy)propanoic acidC42H80NO10P
790.073
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YMDB16273Glycerone phosphatedilithium(1+) ion 1-hydroxy-3-(phosphonatooxy)propan-2-oneC3H5Li2O6P
181.924
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Pathway Proteins

Uniprot ID Gene Name
Locus
Name Type Metabolites
Q03764EKI1
YDR147W
Ethanolamine kinaseEnzyme
P20485CKI1
YLR133W
Choline kinaseEnzyme
Q12385ICT1
YLR099C
1-acylglycerol-3-phosphate O-acyltransferase ICT1Enzyme
P33333SLC1
YDL052C
Probable 1-acyl-sn-glycerol-3-phosphate acyltransferaseEnzyme
Q06510TAZ1
YPR140W
Lysophosphatidylcholine acyltransferaseEnzyme
P32784GPT1
YBL011W
Glycerol-3-phosphate O-acyltransferase 1Enzyme
P36148GPT2
YKR067W
Glycerol-3-phosphate O-acyltransferase 2Enzyme
Q08548ALE1
YOR175C
Lysophospholipid acyltransferaseEnzyme
Q12382DGK1
YOR311C
CTP-dependent diacylglycerol kinase 1Enzyme
Q00055GPD1
YDL022W
Glycerol-3-phosphate dehydrogenase [NAD+] 1Enzyme
Q02979GDE1
YPL110C
Glycerophosphodiester phosphodiesterase GDE1Enzyme
P41911GPD2
YOL059W
Glycerol-3-phosphate dehydrogenase [NAD+] 2, mitochondrialEnzyme
Q08959
YPL206C
Probable glycerophosphodiester phosphodiesterase YPL206CEnzyme
P32191GUT2
YIL155C
Glycerol-3-phosphate dehydrogenase, mitochondrialEnzyme
P25578PGS1
YCL004W
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferaseEnzyme
P17898CPT1
YNL130C
Cholinephosphotransferase 1Enzyme
P13259PCT1
YGR202C
Choline-phosphate cytidylyltransferaseEnzyme
P22140EPT1
YHR123W
Choline/ethanolaminephosphotransferase 1Enzyme
P08456CHO1
YER026C
CDP-diacylglycerol--serine O-phosphatidyltransferaseEnzyme
P33412MUQ1
YGR007W
Ethanolamine-phosphate cytidylyltransferaseEnzyme
P06197PIS1
YPR113W
CDP-diacylglycerol--inositol 3-phosphatidyltransferaseEnzyme
P40471AYR1
YIL124W
NADPH-dependent 1-acyldihydroxyacetone phosphate reductaseEnzyme
P05374PEM1
YGR157W
Phosphatidylethanolamine N-methyltransferaseEnzyme
P38221CDS1
YBR029C
Phosphatidate cytidylyltransferaseEnzyme
P36126SPO14
YKR031C
Phospholipase D1Enzyme
Q08108PLB3
YOL011W
Lysophospholipase 3Enzyme
P39105PLB1
YMR008C
Lysophospholipase 1Enzyme
Q04958NTE1
YML059C
Lysophospholipase NTE1Enzyme
Q03674PLB2
YMR006C
Lysophospholipase 2Enzyme
Q04396LPP1
YDR503C
Lipid phosphate phosphatase 1Enzyme
Q05521DPP1
YDR284C
Diacylglycerol pyrophosphate phosphatase 1Enzyme
Q12043TGL5
YOR081C
Lipase 5Enzyme
P36165TGL4
YKR089C
Lipase 4Enzyme
P38812GEP4
YHR100C
Phosphatidylglycerophosphatase GEP4, mitochondrialEnzyme
P39006PSD1
YNL169C
Phosphatidylserine decarboxylase proenzyme 1, mitochondrialEnzyme
P53037PSD2
YGR170W
Phosphatidylserine decarboxylase proenzyme 2Enzyme
P32567PAH1
Phosphatidic acid phosphohydrolase 1Enzyme
Q06508LOA1
Lysophosphatidic acid:oleoyl-CoA acyltransferase 1Enzyme
Q9C0D9
Ethanolaminephosphotransferase 1