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Biotin Biosynthesis

SourceIDPathway
PathWhizPW002380 ThumbThumb?image type=greyscaleThumb?image type=simple

Pathway Metabolites

YMDB ID Name
CAS Number
IUPAC Name Formula
Weight
Structure
YMDB00075Dethiobiotin
533-48-2
6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanoic acidC10H18N2O3
214.2615
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YMDB00109Adenosine triphosphate
56-65-5
({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acidC10H16N5O13P3
507.181
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YMDB001505'-Deoxyadenosine
4754-39-6
(2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-methyloxolane-3,4-diolC10H13N5O3
251.2419
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YMDB00250S-adenosyl-4-methylthio-2-oxobutanoic acid{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(3-carboxy-3-oxopropyl)methylsulfaniumC15H20N5O6S
398.414
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YMDB00282Biotin
58-85-5
5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acidC10H16N2O3S
244.311
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YMDB00297S-Adenosylmethionine
29908-03-0
[(3S)-3-amino-3-carboxypropyl]({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl})methylsulfaniumC15H23N6O5S
399.445
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YMDB00318L-Methionine
63-68-3
(2S)-2-amino-4-(methylsulfanyl)butanoic acidC5H11NO2S
149.211
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YMDB00438S-Adenosyl-L-methionine
29908-03-0
[(3S)-3-amino-3-carboxypropyl]({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl})methylsulfaniumC15H23N6O5S
399.445
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YMDB00862hydron
12408-02-5
hydronH
1.00794
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YMDB009058-Amino-7-oxononanoic acid
4707-58-8
C9H17NO3
187.2362
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YMDB00907phosphate
14265-44-2
phosphoric acidO4P
94.9714
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YMDB00912Carbon dioxide
124-38-9
methanedioneCO2
44.0095
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YMDB00914ADP
58-64-0
[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acidC10H15N5O10P2
427.2011
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YMDB16140Diaminopimelic acid(2S,6S)-2,6-diaminoheptanedioic acidC7H14N2O4
190.1971
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Pathway Proteins

Uniprot ID Gene Name
Locus
Name Type Metabolites
P32451BIO2
YGR286C
Biotin synthase, mitochondrialEnzyme
P53630BIO4
YNR057C
Dethiobiotin synthetaseEnzyme
P50277BIO3
YNR058W
Adenosylmethionine-8-amino-7-oxononanoate aminotransferaseEnzyme
P53744BIO5
YNR056C
7-keto 8-aminopelargonic acid transporterTransporter