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Nicotinate and nicotinamide metabolism

SourceIDPathway
KEGG00760 Map00760

Pathway Metabolites

YMDB ID Name
CAS Number
IUPAC Name Formula
Weight
Structure
YMDB00007Quinolinic acid
89-00-9
pyridine-2,3-dicarboxylic acidC7H5NO4
167.1189
Thumb
YMDB00101Fumaric acid
110-17-8
(2E)-but-2-enedioic acidC4H4O4
116.0722
Thumb
YMDB00103Nicotinamide riboside
1341-23-7
3-carbamoyl-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1λ⁵-pyridin-1-yliumC11H15N2O5
255.2472
Thumb
YMDB00110NAD
53-84-9
1-[(2R,3R,4S,5R)-5-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1λ⁵-pyridin-1-yliumC21H28N7O14P2
664.433
Thumb
YMDB00138Nicotinamide ribotide
1094-61-7
3-carbamoyl-1-[(2R,3R,4S,5R)-5-[(hydrogen phosphonatooxy)methyl]-3,4-dihydroxyoxolan-2-yl]-1λ⁵-pyridin-1-yliumC11H15N2O8P
334.2192
Thumb
YMDB00157Nicotinate D-ribonucleoside3-carboxy-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1λ⁵-pyridin-1-yliumC11H14NO6
256.232
Thumb
YMDB00175Pyruvic acid
127-17-3
2-oxopropanoic acidC3H4O3
88.0621
Thumb
YMDB00193Nicotinic acid mononucleotide
321-02-8
3-carboxy-1-[(2R,3R,4S,5R)-5-[(hydrogen phosphonatooxy)methyl]-3,4-dihydroxyoxolan-2-yl]-2,3-dihydro-1λ⁵-pyridin-1-yliumC11H16NO9P
337.2198
Thumb
YMDB00224Nicotinic acid
59-67-6
pyridine-3-carboxylic acidC6H5NO2
123.1094
Thumb
YMDB00236Succinic acid semialdehyde
692-29-5
4-oxobutanoic acidC4H6O3
102.0886
Thumb
YMDB00274Niacinamide
98-92-0
pyridine-3-carboxamideC6H6N2O
122.1246
Thumb
YMDB00306deamido-NAD(+)1-[(2R,3R,4S,5R)-5-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carboxy-1λ⁵-pyridin-1-yliumC21H27N6O15P2
665.4178
Thumb
YMDB00322Dihydroxyacetone phosphate
57-04-5
(3-hydroxy-2-oxopropoxy)phosphonic acidC3H7O6P
170.0578
Thumb
YMDB003481-Methylnicotinamide
3106-60-3
3-carbamoyl-1-methylpyridin-1-iumC7H9N2O
137.1592
Thumb
YMDB00412NAD(+)
53-84-9
1-[(2R,3R,4S,5R)-5-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1λ⁵-pyridin-1-yliumC21H28N7O14P2
664.433
Thumb
YMDB00427NADP
53-59-8
1-[(2R,3R,4S,5R)-5-[({[({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1λ⁵-pyridin-1-yliumC21H29N7O17P3
744.4129
Thumb
YMDB00596Iminoaspartic acid
79067-61-1
2-iminobutanedioic acidC4H5NO4
131.0868
Thumb
YMDB00741nicotinic acid D-ribonucleotide3-carboxy-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]-1λ⁵-pyridin-1-yliumC11H15NO9P
336.2119
Thumb
YMDB00857propionic acid
79-09-4
propanoic acidC3H6O2
74.0785
Thumb
YMDB00896L-Aspartic acid
56-84-8
(2S)-2-aminobutanedioic acidC4H7NO4
133.1027
Thumb
YMDB00992succinate semialdehyde
692-29-5
C4H6O3
102.0886
Thumb
YMDB01007nicotinate
59-67-6
pyridine-3-carboxylateC6H4NO2
122.1015
Thumb
YMDB01038fumarate(2-)
110-17-8
C4H2O4
114.0563
Thumb
YMDB01053pyruvate
127-17-3
C3H3O3
87.0541
Thumb

Pathway Proteins

Uniprot ID Gene Name
Locus
Name Type Metabolites
P38795QNS1
YHR074W
Glutamine-dependent NAD(+) synthetaseEnzyme
Q05788PNP1
YLR209C
Purine nucleoside phosphorylaseEnzyme
P25353NPP1
YCR026C
Ectonucleotide pyrophosphatase/phosphodiesterase 1Enzyme
P39997NPP2
YEL016C
Ectonucleotide pyrophosphatase/phosphodiesterase 2Enzyme
P43619BNA6
YFR047C
Nicotinate-nucleotide pyrophosphorylase [carboxylating]Enzyme
P53184PNC1
YGL037C
NicotinamidaseEnzyme
P53164NPY1
YGL067W
NADH pyrophosphataseEnzyme
P53915NRK1
YNL129W
Nicotinamide riboside kinaseEnzyme
P53204NMA2
YGR010W
Nicotinamide-nucleotide adenylyltransferase 2Enzyme
Q06178NMA1
YLR328W
Nicotinamide-nucleotide adenylyltransferase 1Enzyme
P21373UTR1
YJR049C
NAD(+) kinaseEnzyme
P39683NPT1
YOR209C
Nicotinate phosphoribosyltransferaseEnzyme
Q05874NNT1
YLR285W
Putative nicotinamide N-methyltransferaseEnzyme