Canmetcon
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Cysteine and methionine metabolism

SourceIDPathway
KEGG00270 Map00270

Pathway Metabolites

YMDB ID Name
CAS Number
IUPAC Name Formula
Weight
Structure
YMDB00005Sulfate
14808-79-8
sulfuric acidO4S
96.063
Thumb
YMDB000245-(methylsulfanyl)-2,3-dioxopentyl phosphate{[5-(methylsulfanyl)-2,3-dioxopentyl]oxy}phosphonic acidC6H11O6PS
242.187
Thumb
YMDB00034L-aspartic 4-semialdehyde
15106-57-7
(2S)-2-amino-4-oxobutanoic acidC4H7NO3
117.1033
Thumb
YMDB000405-Methylthioribose 1-phosphate
72843-83-5
{[(3R,4S)-3,4-dihydroxy-5-[(methylsulfanyl)methyl]oxolan-2-yl]oxy}phosphonic acidC6H13O7PS
260.202
Thumb
YMDB00046L-Cysteine
52-90-4
(2R)-2-amino-3-sulfanylpropanoic acidC3H7NO2S
121.158
Thumb
YMDB00062Methanethiol
74-93-1
methanethiolCH4S
48.107
Thumb
YMDB000712-Ketobutyric acid
600-18-0
2-oxobutanoic acidC4H6O3
102.0886
Thumb
YMDB00076DL-O-Phosphoserine
17885-08-4
2-amino-3-(phosphonooxy)propanoic acidC3H8NO6P
185.0725
Thumb
YMDB00104L-Homoserine
672-15-1
(2S)-2-amino-4-hydroxybutanoic acidC4H9NO3
119.1192
Thumb
YMDB00112L-Serine
56-45-1
(2S)-2-amino-3-hydroxypropanoic acidC3H7NO3
105.0926
Thumb
YMDB001134-Phospho-L-aspartic acid
22138-53-0
(2S)-2-amino-4-oxo-4-(phosphonooxy)butanoic acidC4H8NO7P
213.0826
Thumb
YMDB00114Sulfite
14265-45-3
sulfurous acidO3S
80.063
Thumb
YMDB001295-Methylthioribulose 1-phosphate
86316-83-8
{[(3R,4S)-3,4-dihydroxy-5-(methylsulfanyl)-2-oxopentyl]oxy}phosphonic acidC6H13O7PS
260.202
Thumb
YMDB00130S-Adenosylmethioninamine
22365-13-5
{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(3-aminopropyl)methylsulfaniumC14H23N6O3S
355.436
Thumb
YMDB00154L-Alanine
56-41-7
(2S)-2-aminopropanoic acidC3H7NO2
89.0932
Thumb
YMDB00158O-Acetyl-L-homoserine
7540-67-2
(2S)-4-(acetyloxy)-2-aminobutanoic acidC6H11NO4
161.1558
Thumb
YMDB00160Glutathione
70-18-8
(2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-sulfanylethyl]carbamoyl}butanoic acidC10H17N3O6S
307.323
Thumb
YMDB00175Pyruvic acid
127-17-3
2-oxopropanoic acidC3H4O3
88.0621
Thumb
YMDB001785'-Methylthioadenosine
2457-80-9
(2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-[(methylsulfanyl)methyl]oxolane-3,4-diolC11H15N5O3S
297.334
Thumb
YMDB001851,2-Dihydroxy-3-keto-5-methylthiopentene
746507-19-7
(1Z)-1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-oneC6H10O3S
162.207
Thumb
YMDB00198S-Adenosylhomocysteine
979-92-0
(2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}sulfanyl)butanoic acidC14H20N6O5S
384.411
Thumb
YMDB00245L-Cystathionine
56-88-2
(2S)-2-amino-4-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}butanoic acidC7H14N2O4S
222.262
Thumb
YMDB00297S-Adenosylmethionine
29908-03-0
[(3S)-3-amino-3-carboxypropyl]({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl})methylsulfaniumC15H23N6O5S
399.445
Thumb
YMDB00303Thiosulfate
14383-50-7
sulfanesulfonic acidO3S2
112.128
Thumb
YMDB00318L-Methionine
63-68-3
(2S)-2-amino-4-(methylsulfanyl)butanoic acidC5H11NO2S
149.211
Thumb
YMDB004214-Methylthio-2-oxobutanoate
583-92-6
4-(methylsulfanyl)-2-oxobutanoic acidC5H8O3S
148.18
Thumb
YMDB00438S-Adenosyl-L-methionine
29908-03-0
[(3S)-3-amino-3-carboxypropyl]({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl})methylsulfaniumC15H23N6O5S
399.445
Thumb
YMDB00520L-Homocysteine
6027-13-0
(2S)-2-amino-4-sulfanylbutanoic acidC4H9NO2S
135.185
Thumb
YMDB00652O-acetyl-L-serine
5147-00-2
(2S)-3-(acetyloxy)-2-aminopropanoic acidC5H9NO4
147.1293
Thumb
YMDB00653Hydrogen sulfide
7783-06-4
hydrogen sulfideH2S
34.081
Thumb
YMDB00690L-cysteinylglycine
70-18-8
2-[(2R)-2-amino-3-sulfanylpropanamido]acetic acidC5H10N2O3S
178.21
Thumb
YMDB00761O-Phospho-L-serine
407-41-0
(2S)-2-amino-3-(phosphonooxy)propanoic acidC3H8NO6P
185.0725
Thumb
YMDB00861Cystine
56-89-3
(2R)-2-amino-3-{[(2R)-2-amino-2-carboxyethyl]disulfanyl}propanoic acidC6H12N2O4S2
240.3
Thumb
YMDB00886L-Cystine
56-89-3
(2R)-2-amino-3-{[(2R)-2-amino-2-carboxyethyl]disulfanyl}propanoic acidC6H12N2O4S2
240.3
Thumb
YMDB00896L-Aspartic acid
56-84-8
(2S)-2-aminobutanedioic acidC4H7NO4
133.1027
Thumb
YMDB00913D-Cysteine
921-01-7
(2S)-2-amino-3-sulfanylpropanoic acidC3H7NO2S
121.158
Thumb
YMDB00917O-Succinyl-L-homoserine
1492-23-5
(2S)-2-amino-4-[(3-carboxypropanoyl)oxy]butanoic acidC8H13NO6
219.1919
Thumb
YMDB00961S-Methyl-5-thio-alpha-D-ribose 1-phosphate{[(2R,3R,4S,5S)-3,4-dihydroxy-5-[(methylsulfanyl)methyl]oxolan-2-yl]oxy}phosphonic acidC6H13O7PS
260.202
Thumb
YMDB00980(5-Deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium
22365-13-5
{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(3-aminopropyl)methylsulfaniumC14H23N6O3S
355.436
Thumb
YMDB010112-oxobutanoate
600-18-0
C4H5O3
101.0807
Thumb
YMDB01022L-aspartate 4-semialdehyde
15106-57-7
(2S)-2-amino-4-oxobutanoateC4H6NO3
116.0953
Thumb
YMDB01053pyruvate
127-17-3
C3H3O3
87.0541
Thumb
YMDB010674-phospho-L-aspartate
22138-53-0
C4H5NO7P
210.0588
Thumb
YMDB01335Ethoxy ethene
109-92-2
ethoxyetheneC4H8O
72.1057
Thumb

Pathway Proteins

Uniprot ID Gene Name
Locus
Name Type Metabolites
P32626UTR4
YEL038W
Enolase-phosphatase E1Enzyme
P47095MDE1
YJR024C
Methylthioribulose-1-phosphate dehydrataseEnzyme
P13663HOM2
YDR158W
Aspartate-semialdehyde dehydrogenaseEnzyme
P36088
YKL069W
Free methionine-R-sulfoxide reductaseEnzyme
Q06489MRI1
YPR118W
Methylthioribose-1-phosphate isomeraseEnzyme
P08465MET2
YNL277W
Homoserine O-acetyltransferaseEnzyme
P53206
YGR012W
Putative cysteine synthaseEnzyme
Q04533
YML082W
Putative cystathionine gamma-synthase YML082WEnzyme
P06106MET17
YLR303W
Protein MET17Enzyme
P31373CYS3
YAL012W
Cystathionine gamma-lyaseEnzyme
Q12198
YLL058W
Putative cystathionine gamma-synthase YLL058WEnzyme
P47164STR2
YJR130C
Cystathionine gamma-synthaseEnzyme
P39954SAH1
YER043C
AdenosylhomocysteinaseEnzyme
P05694MET6
YER091C
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferaseEnzyme
P0CF21SDL1
YIL167W
L-serine dehydrataseEnzyme
P53101STR3
YGL184C
Cystathionine beta-lyaseEnzyme
P43623IRC7
YFR055W
Putative cystathionine beta-lyaseEnzyme
P10659SAM1
YLR180W
S-adenosylmethionine synthase 1Enzyme
P10869HOM3
YER052C
AspartokinaseEnzyme
P32582CYS4
YGR155W
Cystathionine beta-synthaseEnzyme
P38840ARO9
YHR137W
Aromatic amino acid aminotransferase 2Enzyme
P53090ARO8
YGL202W
Aromatic amino acid aminotransferase 1Enzyme
Q12455SPE4
YLR146C
Spermine synthaseEnzyme
Q12074SPE3
YPR069C
Spermidine synthaseEnzyme
P21182SPE2
YOL052C
S-adenosylmethionine decarboxylase proenzymeEnzyme
Q01802AAT1
YKL106W
Aspartate aminotransferase, mitochondrialEnzyme
P23542AAT2
YLR027C
Aspartate aminotransferase, cytoplasmicEnzyme
Q12525MHT1
YLL062C
Homocysteine S-methyltransferase 1Enzyme
Q08985SAM4
YPL273W
Homocysteine S-methyltransferase 2Enzyme
P31116HOM6
YJR139C
Homoserine dehydrogenaseEnzyme
P19358SAM2
YDR502C
S-adenosylmethionine synthase 2Enzyme