Canmetcon
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Identification
YMDB IDYMDB16175
NameSelenomethionine
SpeciesNot Available
StrainBrewer's yeast
DescriptionNot Available
Structure
Thumb
Synonyms
  • (+-)-Selenomethionine
  • Selenium methionine
  • Seleno-DL-methionine
  • (2S)-2-Amino-4-(methylseleno)butanoate
  • (2S)-2-Amino-4-(methylseleno)butanoic acid
  • (S)-2-Amino-4-(methylseleno)-butanoate
  • (S)-2-Amino-4-(methylseleno)-butanoic acid
  • (S)-2-Amino-4-(methylseleno)butanoate
  • (S)-2-Amino-4-(methylseleno)butanoic acid
  • (S)-2-Amino-4-(methylseleno)butyric acid
  • 2-Amino-4-(methylseleno)butanoate
  • 2-Amino-4-(methylseleno)butanoic acid
  • 2-Amino-4-(methylselenyl)butyrate
  • 2-Amino-4-(methylselenyl)butyric acid
  • DL-Selenomethionine
  • L(+)-Selenomethionine
  • L-2-Amino-4-(methylselenyl)-butyric acid
  • L-Selenomethionine
  • L-Selenomethioninum
  • MSE
  • Selenium-L-methionine
  • Seleno-D,L-methionine
  • Seleno-L-methionine
  • Selenomethionine se 75
  • SeMet
  • Sethotope
  • Selenomethionine hydrochloride, (S)-isomer
  • Selenomethionine, (S)-isomer
  • Radioselenomethionine
  • Selenomethionine, (+,-)-isomer
  • Selenomethionine, (R)-isomer
  • Se 75, selenomethionine
CAS numberNot Available
WeightAverage: 196.11
Monoisotopic: 196.995500429
InChI KeyRJFAYQIBOAGBLC-UHFFFAOYSA-N
InChIInChI=1S/C5H11NO2Se/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)
IUPAC Name2-amino-4-(methylselanyl)butanoic acid
Traditional IUPAC Name(+,-)-selenomethionine
Chemical FormulaC5H11NO2Se
SMILESC[Se]CCC(N)C(O)=O
Chemical Taxonomy
Description belongs to the class of organic compounds known as alpha amino acids. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon).
KingdomOrganic compounds
Super ClassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
Sub ClassAmino acids, peptides, and analogues
Direct ParentAlpha amino acids
Alternative Parents
Substituents
  • Alpha-amino acid
  • Fatty acid
  • Amino acid
  • Carboxylic acid
  • Monocarboxylic acid or derivatives
  • Selenoether
  • Organic nitrogen compound
  • Hydrocarbon derivative
  • Organic oxide
  • Primary amine
  • Organoselenium compound
  • Organooxygen compound
  • Organonitrogen compound
  • Organopnictogen compound
  • Primary aliphatic amine
  • Organic oxygen compound
  • Carbonyl group
  • Amine
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External Descriptors
Physical Properties
StateSolid
Charge0
Melting pointNot Available
Experimental Properties
PropertyValueReference
Water SolubilityNot AvailablePhysProp
LogPNot AvailablePhysProp
Predicted Properties
PropertyValueSource
Water Solubility109 g/LALOGPS
logP-2.5ALOGPS
logP-3.3ChemAxon
logS-0.25ALOGPS
pKa (Strongest Acidic)1.56ChemAxon
pKa (Strongest Basic)9.5ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area63.32 ŲChemAxon
Rotatable Bond Count4ChemAxon
Refractivity42.91 m³·mol⁻¹ChemAxon
Polarizability14.92 ųChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Biological Properties
Cellular LocationsNot Available
Organoleptic PropertiesNot Available
SMPDB Pathways
Selenocompound metabolismPW002472 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG Pathways
Selenocompound metabolismec00450 Map00450
SMPDB Reactions
Selenohomocysteine + 5-Methyltetrahydropteroyltri-L-glutamateSelenomethionine + Tetrahydropteroyltri-L-glutamate
Adenosine triphosphate + tRNA(Met) + SelenomethionineAdenosine monophosphate + Pyrophosphate + Selenomethionyl-tRNA(Met)
Selenomethionine + watermethylselenol + Ammonia + 2-Ketobutyric acid
KEGG ReactionsNot Available
Concentrations
Intracellular ConcentrationsNot Available
Extracellular ConcentrationsNot Available
Spectra
Spectra
References
References:Not Available
Synthesis Reference:Not Available
External Links:
ResourceLink
CHEBI ID27585
HMDB IDHMDB0003966
Pubchem Compound ID15103
Kegg IDC05335
ChemSpider ID14375
FOODB IDFDB012370
Wikipedia IDSelenomethionine
BioCyc IDNot Available

Enzymes

General function:
Involved in pyridoxal phosphate binding
Specific function:
L-cystathionine + H(2)O = L-cysteine + NH(3) + 2-oxobutanoate
Gene Name:
CYS3
Uniprot ID:
P31373
Molecular weight:
42541.69922
Reactions
L-cystathionine + H(2)O → L-cysteine + NH(3) + 2-oxobutanoate.
General function:
Involved in 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity
Specific function:
Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Gene Name:
MET6
Uniprot ID:
P05694
Molecular weight:
85859.20313
Reactions
5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine → tetrahydropteroyltri-L-glutamate + L-methionine.
General function:
Involved in nucleotide binding
Specific function:
ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)
Gene Name:
MSM1
Uniprot ID:
P22438
Molecular weight:
66733.89844
Reactions
ATP + L-methionine + tRNA(Met) → AMP + diphosphate + L-methionyl-tRNA(Met).
General function:
Involved in nucleotide binding
Specific function:
ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)
Gene Name:
MES1
Uniprot ID:
P00958
Molecular weight:
85677.39844
Reactions
ATP + L-methionine + tRNA(Met) → AMP + diphosphate + L-methionyl-tRNA(Met).