{"ymdb_id":"YMDB01559","created_at":"2011-08-11T21:19:42.000Z","updated_at":"2016-10-18T17:12:04.000Z","name":"2-Hydroxyvalerate","cas":"617-31-2","state":"Solid","melting_point":"34 oC","description":"2-Hydroxyvalerate is a 2-hydroxy acid which can be used as a substrate by the flavocytochrome b2 (L-lactate dehydrogenase) from Saccharomyces cerevisiae. [PMID: 8053908]","experimental_water_solubility":null,"experimental_logp_hydrophobicity":"0.45 [SANGSTER (1993)]","location":null,"synthesis_reference":null,"chebi_id":"60647","hmdb_id":"HMDB01863","kegg_id":null,"pubchem_id":"98009","cs_id":"88482","foodb_id":null,"wikipedia_link":null,"biocyc_id":null,"iupac":"2-hydroxypentanoic acid","traditional_iupac":"pentanoic acid, 2-hydroxy-","logp":"0.49526154199999994","pka":"14.284641269964371","alogps_solubility":"2.04e+02 g/l","alogps_logp":"0.26","alogps_logs":"0.24","acceptor_count":"3","donor_count":"2","rotatable_bond_count":"3","polar_surface_area":"57.53","refractivity":"27.9648","polarizability":"11.834773660076316","formal_charge":"0","physiological_charge":"-1","pka_strongest_basic":"-3.7973131043245454","pka_strongest_acidic":"4.1421099451224626","bioavailability":"1","number_of_rings":"0","rule_of_five":"1","ghose_filter":"0","veber_rule":"0","mddr_like_rule":"0","synonyms":["(+-)-2-Hydroxypentanoate","(+-)-2-Hydroxypentanoic acid","(S)-2-Hydroxyvaleric acid","2-Hydroxy-pentanoate","2-Hydroxy-pentanoic acid","2-Hydroxypentanoate","2-Hydroxypentanoic acid","2-Hydroxyvalerate","2-Hydroxyvaleric acid","a-Hydroxy-N-valerate","a-Hydroxy-N-valeric acid","a-Hydroxyvalerate","a-Hydroxyvaleric acid","alpha-Hydroxy-N-valerate","alpha-Hydroxy-N-valeric acid","alpha-Hydroxyvalerate","alpha-Hydroxyvaleric acid","DL-2-Hydroxy valerate","α-hydroxy-N-valerate","α-hydroxy-N-valeric acid","α-hydroxyvalerate","α-hydroxyvaleric acid"],"pathways":[],"growth_conditions":[{"growth_media":"YEB media with 0.5 mM glucose","concentration":"3035.0","concentration_units":"\u0026#181;M","error":"152.0"}],"references":[{"pubmed_id":17439666,"citation":"Castrillo, J. I., Zeef, L. A., Hoyle, D. C., Zhang, N., Hayes, A., Gardner, D. C., Cornell, M. J., Petty, J., Hakes, L., Wardleworth, L., Rash, B., Brown, M., Dunn, W. B., Broadhurst, D., O'Donoghue, K., Hester, S. S., Dunkley, T. P., Hart, S. R., Swainston, N., Li, P., Gaskell, S. J., Paton, N. W., Lilley, K. S., Kell, D. B., Oliver, S. G. (2007). \"Growth control of the eukaryote cell: a systems biology study in yeast.\" J Biol 6:4."}],"proteins":[]}