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Identification |
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YMDB ID | YMDB00918 |
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Name | l-Glutamic-gamma-semialdehyde |
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Species | Saccharomyces cerevisiae |
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Strain | Baker's yeast |
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Description | L-Glutamic gamma-semialdehyde, also known as L-glutamate 5-semialdehyde or 5-oxo-L-norvaline, belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom. L-Glutamic gamma-semialdehyde is a very strong basic compound (based on its pKa). L-Glutamic gamma-semialdehyde exists in all living species, ranging from bacteria to humans. |
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Structure | |
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Synonyms | - glutamate-semialdehyde
- glutamic gamma-semialdehyde
- L-glutamate 5-semialdehyde
- L-glutamate gamma-semialdehyde
- L-glutamate-5-semialdehyde
- L-Glutamic-gamma-semialdehyde
- 5-oxo-L-Norvaline
- L-Glutamic acid 5-semialdehyde
- L-Glutamate g-semialdehyde
- L-Glutamate γ-semialdehyde
- L-Glutamic acid g-semialdehyde
- L-Glutamic acid gamma-semialdehyde
- L-Glutamic acid γ-semialdehyde
- L-Glutamic g-semialdehyde
- L-Glutamic γ-semialdehyde
- L-Glutamate-gamma-semialdehyde
- gamma-Glutamyl semialdehyde
- Glutamate gamma-semialdehyde
- Glutamic acid gamma-semialdehyde
- Glutamic acid gamma-semialdehyde, (L)-isomer
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CAS number | 496-92-4 |
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Weight | Average: 131.1299 Monoisotopic: 131.058243159 |
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InChI Key | KABXUUFDPUOJMW-BYPYZUCNSA-N |
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InChI | InChI=1S/C5H9NO3/c6-4(5(8)9)2-1-3-7/h3-4H,1-2,6H2,(H,8,9)/t4-/m0/s1 |
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IUPAC Name | (2S)-2-amino-5-oxopentanoic acid |
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Traditional IUPAC Name | 4-carboxy-4-aminobutanal |
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Chemical Formula | C5H9NO3 |
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SMILES | [H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])=O |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom. |
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Kingdom | Organic compounds |
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Super Class | Organic acids and derivatives |
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Class | Carboxylic acids and derivatives |
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Sub Class | Amino acids, peptides, and analogues |
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Direct Parent | L-alpha-amino acids |
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Alternative Parents | |
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Substituents | - L-alpha-amino acid
- Fatty acid
- Alpha-hydrogen aldehyde
- Amino acid
- Carboxylic acid
- Monocarboxylic acid or derivatives
- Aldehyde
- Hydrocarbon derivative
- Organic oxide
- Primary amine
- Organooxygen compound
- Organonitrogen compound
- Organopnictogen compound
- Primary aliphatic amine
- Organic oxygen compound
- Carbonyl group
- Amine
- Organic nitrogen compound
- Aliphatic acyclic compound
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Molecular Framework | Aliphatic acyclic compounds |
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External Descriptors | |
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Physical Properties |
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State | Solid |
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Charge | 0 |
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Melting point | Not Available |
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Experimental Properties | Property | Value | Reference |
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Water Solubility | Not Available | PhysProp | LogP | Not Available | PhysProp |
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Predicted Properties | |
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Biological Properties |
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Cellular Locations | |
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Organoleptic Properties | Not Available |
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SMPDB Pathways | |
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KEGG Pathways | Arginine and proline metabolism | ec00330 |  |
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SMPDB Reactions | |
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KEGG Reactions | |
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Concentrations |
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Intracellular Concentrations | Not Available |
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Extracellular Concentrations | Not Available |
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Spectra |
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Spectra | Spectrum Type | Description | Splash Key | View |
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Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive | splash10-059l-9000000000-c907c5e28c6d3b047532 | JSpectraViewer | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (1 TMS) - 70eV, Positive | splash10-000i-9200000000-b09702360bf061bd64db | JSpectraViewer | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-02a9-9700000000-ffc8c81a881bac7a0ca7 | JSpectraViewer | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-00kr-9100000000-7061d8b19402303b61af | JSpectraViewer | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-0a4l-9000000000-fa50d608bfaec666722d | JSpectraViewer | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-001i-1900000000-485c1c464e6d065cb4ac | JSpectraViewer | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-01q9-7900000000-cd2ef70374a324d28ee0 | JSpectraViewer | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-0006-9000000000-8685f6b3a1d6936c24c3 | JSpectraViewer |
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References |
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References: | - UniProt Consortium (2011). "Ongoing and future developments at the Universal Protein Resource." Nucleic Acids Res 39:D214-D219.21051339
- Scheer, M., Grote, A., Chang, A., Schomburg, I., Munaretto, C., Rother, M., Sohngen, C., Stelzer, M., Thiele, J., Schomburg, D. (2011). "BRENDA, the enzyme information system in 2011." Nucleic Acids Res 39:D670-D676.21062828
- Herrgard, M. J., Swainston, N., Dobson, P., Dunn, W. B., Arga, K. Y., Arvas, M., Bluthgen, N., Borger, S., Costenoble, R., Heinemann, M., Hucka, M., Le Novere, N., Li, P., Liebermeister, W., Mo, M. L., Oliveira, A. P., Petranovic, D., Pettifer, S., Simeonidis, E., Smallbone, K., Spasic, I., Weichart, D., Brent, R., Broomhead, D. S., Westerhoff, H. V., Kirdar, B., Penttila, M., Klipp, E., Palsson, B. O., Sauer, U., Oliver, S. G., Mendes, P., Nielsen, J., Kell, D. B. (2008). "A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology." Nat Biotechnol 26:1155-1160.18846089
- Takagi, H., Takaoka, M., Kawaguchi, A., Kubo, Y. (2005). "Effect of L-proline on sake brewing and ethanol stress in Saccharomyces cerevisiae." Appl Environ Microbiol 71:8656-8662.16332860
- Brandriss, M. C., Magasanik, B. (1979). "Genetics and physiology of proline utilization in Saccharomyces cerevisiae: enzyme induction by proline." J Bacteriol 140:498-503.387737
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Synthesis Reference: | Not Available |
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External Links: | |
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