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Identification
YMDB IDYMDB00286
NameD-Glucose
SpeciesSaccharomyces cerevisiae
StrainBaker's yeast
DescriptionD-Glucose, also known as D-GLC or cerelose, belongs to the class of organic compounds known as hexoses. These are monosaccharides in which the sugar unit is a is a six-carbon containing moeity. D-Glucose is an extremely weak basic (essentially neutral) compound (based on its pKa). D-Glucose exists in all living species, ranging from bacteria to humans. Within yeast, D-glucose participates in a number of enzymatic reactions. In particular, D-glucose can be converted into glucose 6-phosphate; which is mediated by the enzyme hexokinase-2. In addition, D-glucose can be biosynthesized from trehalose; which is mediated by the enzyme alpha,alpha-trehalase. In yeast, D-glucose is involved in the metabolic pathway called the starch and sucrose metabolism pathway. D-Glucose is a potentially toxic compound.
Structure
Thumb
Synonyms
  • (+)-Glucose
  • Anhydrous dextrose
  • Cerelose
  • Clintose L
  • Corn sugar
  • CPC hydrate
  • D(+)-Glucose
  • Dextropur
  • Dextrose
  • Dextrosol
  • Glucodin
  • Glucolin
  • Glucose
  • Goldsugar
  • Grape sugar
  • Meritose
  • Roferose ST
  • Vadex
  • D-GLC
  • D-GLCP
  • GLC-OH
  • D-Glucopyranose
  • Purified glucose
  • Cerelose 2001
  • Clearsweet 95
  • Staleydex 111
  • Staleydex 95m
  • Tabfine 097(HS)
  • D Glucose
  • Glucose, (DL)-isomer
  • Glucose, (L)-isomer
  • Glucose, (beta-D)-isomer
  • Glucose monohydrate
  • Glucose, (alpha-D)-isomer
  • L Glucose
  • L-Glucose
  • Dextrose, anhydrous
  • Monohydrate, glucose
CAS number50-99-7
WeightAverage: 180.1559
Monoisotopic: 180.063388116
InChI KeyWQZGKKKJIJFFOK-GASJEMHNSA-N
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6?/m1/s1
IUPAC Name(3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol
Traditional IUPAC Nameglucose
Chemical FormulaC6H12O6
SMILES[H]OC([H])([H])[C@@]1([H])OC([H])(O[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
Chemical Taxonomy
Description belongs to the class of organic compounds known as hexoses. These are monosaccharides in which the sugar unit is a is a six-carbon containing moeity.
KingdomOrganic compounds
Super ClassOrganic oxygen compounds
ClassOrganooxygen compounds
Sub ClassCarbohydrates and carbohydrate conjugates
Direct ParentHexoses
Alternative Parents
Substituents
  • Hexose monosaccharide
  • Oxane
  • Secondary alcohol
  • Hemiacetal
  • Oxacycle
  • Organoheterocyclic compound
  • Polyol
  • Hydrocarbon derivative
  • Primary alcohol
  • Alcohol
  • Aliphatic heteromonocyclic compound
Molecular FrameworkAliphatic heteromonocyclic compounds
External Descriptors
Physical Properties
StateSolid
Charge0
Melting point146-150 °C
Experimental Properties
PropertyValueReference
Water Solubility1200 mg/mL at 30 oC [MULLIN,JW (1972)]PhysProp
LogP-3.24 [SANGSTER (1994)]PhysProp
Predicted Properties
PropertyValueSource
Water Solubility782 g/LALOGPS
logP-2.6ALOGPS
logP-2.9ChemAxon
logS0.64ALOGPS
pKa (Strongest Acidic)11.3ChemAxon
pKa (Strongest Basic)-3ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count6ChemAxon
Hydrogen Donor Count5ChemAxon
Polar Surface Area110.38 ŲChemAxon
Rotatable Bond Count1ChemAxon
Refractivity35.92 m³·mol⁻¹ChemAxon
Polarizability16.37 ųChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Biological Properties
Cellular Locations
  • extracellular
  • endoplasmic reticulum
  • vacuole
  • cytoplasm
Organoleptic PropertiesNot Available
SMPDB Pathways
Amino sugar and nucleotide sugar metabolismPW002413 ThumbThumb?image type=greyscaleThumb?image type=simple
Ethanol fermentationPW002448 ThumbThumb?image type=greyscaleThumb?image type=simple
Glycolysis IPW002386 ThumbThumb?image type=greyscaleThumb?image type=simple
Starch and sucrose metabolismPW002481 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG Pathways
Amino sugar and nucleotide sugar metabolismec00520 Map00520
Galactose metabolismec00052 Map00052
Glycolysis / Gluconeogenesisec00010 Map00010
Pentose phosphate pathwayec00030 Map00030
Starch and sucrose metabolismec00500 Map00500
SMPDB Reactions
D-Glucose + Adenosine triphosphateGlucose 6-phosphate + ADP
Glucose 1-phosphate + waterD-Glucose + phosphate
Glucosylceramide + waterCeramide (d18:1/18:0) + D-Glucose
Trehalose + waterD-Glucose
KEGG Reactions
water + TrehaloseD-Glucose
D-Glucose + glycan G10599glycan G00008
Maltose + waterD-Glucose
D-Glucose + NADPH + hydronNADP + D-glucitol
water + (1->3)-beta-D-glucan D-Glucose
Concentrations
Intracellular Concentrations
Intracellular ConcentrationSubstrateGrowth ConditionsStrainCitation
1500 ± 100 µM 1% wt/vol glucose 2%wt vol yeast nitrogen baseaerobic Baker's yeastPMID: 9457857
2122 ± 106 µM YEB media with 0.5 mM glucoseaerobicBaker's yeastExperimentally Determined
Not Available
1500 ± 500 µM Synthetic medium with 1% glucose and 0.1% yeast extractaerobicBaker's yeastPMID: 16623706
Conversion Details Here
Extracellular ConcentrationsNot Available
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyView
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (5 TMS)splash10-00kb-1931000000-ec21c3af97621f7bf95aJSpectraViewer | MoNA
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (5 TMS)splash10-0fr2-1920000000-f53c5f0d5ad84d32679fJSpectraViewer | MoNA
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (5 TMS; 1 MEOX)splash10-00di-9821000000-dbc697213e3b7cc9d4feJSpectraViewer | MoNA
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (5 TMS; 1 MEOX)splash10-00di-9621000000-9d1d8057758d3da8cacaJSpectraViewer | MoNA
GC-MSGC-MS Spectrum - GC-MS (4 TMS)splash10-014i-2490000000-3ed4c4fd34c05bad95f7JSpectraViewer | MoNA
GC-MSGC-MS Spectrum - GC-MS (1 MEOX; 5 TMS)splash10-066r-1952000000-3378cb724e551e8b0267JSpectraViewer | MoNA
GC-MSGC-MS Spectrum - GC-MS (5 TMS)splash10-0udl-0690000000-c8fda4276ff69235f30dJSpectraViewer | MoNA
GC-MSGC-MS Spectrum - GC-MS (1 MEOX; 5 TMS)splash10-0ldi-1942000000-5d531ed23a4e82023d1cJSpectraViewer | MoNA
GC-MSGC-MS Spectrum - GC-MS (5 TMS)splash10-0udi-0790000000-7ebe75cd633c58d761faJSpectraViewer | MoNA
GC-MSGC-MS Spectrum - GC-EI-TOF (Non-derivatized)splash10-00kb-1931000000-ec21c3af97621f7bf95aJSpectraViewer | MoNA
GC-MSGC-MS Spectrum - GC-EI-TOF (Non-derivatized)splash10-0fr2-1920000000-f53c5f0d5ad84d32679fJSpectraViewer | MoNA
GC-MSGC-MS Spectrum - GC-EI-TOF (Non-derivatized)splash10-00di-9821000000-dbc697213e3b7cc9d4feJSpectraViewer | MoNA
GC-MSGC-MS Spectrum - GC-EI-TOF (Non-derivatized)splash10-00di-9621000000-9d1d8057758d3da8cacaJSpectraViewer | MoNA
GC-MSGC-MS Spectrum - GC-MS (Non-derivatized)splash10-014i-2490000000-3ed4c4fd34c05bad95f7JSpectraViewer | MoNA
GC-MSGC-MS Spectrum - GC-MS (Non-derivatized)splash10-066r-1952000000-3378cb724e551e8b0267JSpectraViewer | MoNA
GC-MSGC-MS Spectrum - GC-MS (Non-derivatized)splash10-0udl-0690000000-c8fda4276ff69235f30dJSpectraViewer | MoNA
GC-MSGC-MS Spectrum - GC-MS (Non-derivatized)splash10-0ldi-1942000000-5d531ed23a4e82023d1cJSpectraViewer | MoNA
GC-MSGC-MS Spectrum - GC-MS (Non-derivatized)splash10-0udi-0790000000-7ebe75cd633c58d761faJSpectraViewer | MoNA
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positivesplash10-0np0-9700000000-e8d638dc817e46b97d7bJSpectraViewer
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (5 TMS) - 70eV, Positivesplash10-004i-6122690000-eaf6f7adf34ccd0c667bJSpectraViewer
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 10V, N/A (Annotated)splash10-0002-9300000000-839f41cf94a071fcdb37JSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 25V, N/A (Annotated)splash10-0002-9000000000-807f75d14f3d0b66f5bdJSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 40V, N/A (Annotated)splash10-000t-9000000000-b89668f86992a8363664JSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Negativesplash10-000i-7900000000-9a673c2e4b82ca397421JSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Negativesplash10-0a4r-9100000000-b70415588e768ddce5efJSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Negativesplash10-0a4i-9000000000-73dc84dd88d8ae69fe02JSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Negativesplash10-0a4i-9000000000-ba39d4ed9431a1d01eabJSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Negativesplash10-0a4i-9000000000-a61efd1469735758b317JSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ , negativesplash10-000i-7900000000-9a673c2e4b82ca397421JSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ , negativesplash10-0a4r-9100000000-9c25b149885d8a48aab5JSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ , negativesplash10-0a4i-9000000000-76d92ea96364c24ecfb0JSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ , negativesplash10-0a4i-9000000000-ba39d4ed9431a1d01eabJSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ , negativesplash10-0a4i-9000000000-a61efd1469735758b317JSpectraViewer | MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-01q9-0900000000-b0bc47623e7b2ca31c02JSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-03ea-3900000000-648e1637af29cf2a3518JSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-0007-9200000000-9e6f46a1cbf52d6e347aJSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-004i-2900000000-a4ec4f0b1e29e360a952JSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-01t9-6900000000-7b3ea9c64ecc8d4ac867JSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-052f-9100000000-ec2bf4918640a0a36398JSpectraViewer
1D NMR1H NMR SpectrumNot AvailableJSpectraViewer
1D NMR13C NMR SpectrumNot AvailableJSpectraViewer
2D NMR[1H,13C] 2D NMR SpectrumNot AvailableJSpectraViewer
References
References:
  • UniProt Consortium (2011). "Ongoing and future developments at the Universal Protein Resource." Nucleic Acids Res 39:D214-D219.21051339
  • Scheer, M., Grote, A., Chang, A., Schomburg, I., Munaretto, C., Rother, M., Sohngen, C., Stelzer, M., Thiele, J., Schomburg, D. (2011). "BRENDA, the enzyme information system in 2011." Nucleic Acids Res 39:D670-D676.21062828
  • Teusink, B., Diderich, J. A., Westerhoff, H. V., van Dam, K., Walsh, M. C. (1998). "Intracellular glucose concentration in derepressed yeast cells consuming glucose is high enough to reduce the glucose transport rate by 50%." J Bacteriol 180:556-562.9457857
  • Herrgard, M. J., Swainston, N., Dobson, P., Dunn, W. B., Arga, K. Y., Arvas, M., Bluthgen, N., Borger, S., Costenoble, R., Heinemann, M., Hucka, M., Le Novere, N., Li, P., Liebermeister, W., Mo, M. L., Oliveira, A. P., Petranovic, D., Pettifer, S., Simeonidis, E., Smallbone, K., Spasic, I., Weichart, D., Brent, R., Broomhead, D. S., Westerhoff, H. V., Kirdar, B., Penttila, M., Klipp, E., Palsson, B. O., Sauer, U., Oliver, S. G., Mendes, P., Nielsen, J., Kell, D. B. (2008). "A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology." Nat Biotechnol 26:1155-1160.18846089
  • Senac, T., Hahn-Hagerdal, B. (1990). "Intermediary Metabolite Concentrations in Xylulose- and Glucose-Fermenting Saccharomyces cerevisiae Cells." Appl Environ Microbiol 56:120-126.16348083
  • Maitra, P. K., Lobo, Z. (1983). "Genetics of yeast glucokinase." Genetics 105:501-515.6357942
  • Entian, K. D., Kopetzki, E., Frohlich, K. U., Mecke, D. (1984). "Cloning of hexokinase isoenzyme PI from Saccharomyces cerevisiae: PI transformants confirm the unique role of hexokinase isoenzyme PII for glucose repression in yeasts." Mol Gen Genet 198:50-54.6394965
  • Wang, Z., Wilson, W. A., Fujino, M. A., Roach, P. J. (2001). "Antagonistic controls of autophagy and glycogen accumulation by Snf1p, the yeast homolog of AMP-activated protein kinase, and the cyclin-dependent kinase Pho85p." Mol Cell Biol 21:5742-5752.11486014
  • van der Aart, Q. J., Kleine, K., Steensma, H. Y. (1996). "Sequence analysis of the 43 kb CRM1-YLM9-PET54-DIE2-SMI1-PHO81-YHB4-PFK1 region from the right arm of Saccharomyces cerevisiae chromosome VII." Yeast 12:385-390.8701610
  • Burda, P., Aebi, M. (1998). "The ALG10 locus of Saccharomyces cerevisiae encodes the alpha-1,2 glucosyltransferase of the endoplasmic reticulum: the terminal glucose of the lipid-linked oligosaccharide is required for efficient N-linked glycosylation." Glycobiology 8:455-462.9597543
  • Luttik, M. A., Overkamp, K. M., Kotter, P., de Vries, S., van Dijken, J. P., Pronk, J. T. (1998). "The Saccharomyces cerevisiae NDE1 and NDE2 genes encode separate mitochondrial NADH dehydrogenases catalyzing the oxidation of cytosolic NADH." J Biol Chem 273:24529-24534.9733747
  • Tettelin, H., Agostoni Carbone, M. L., Albermann, K., Albers, M., Arroyo, J., Backes, U., Barreiros, T., Bertani, I., Bjourson, A. J., Bruckner, M., Bruschi, C. V., Carignani, G., Castagnoli, L., Cerdan, E., Clemente, M. L., Coblenz, A., Coglievina, M., Coissac, E., Defoor, E., Del Bino, S., Delius, H., Delneri, D., de Wergifosse, P., Dujon, B., Kleine, K., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII." Nature 387:81-84.9169869
  • Teste, M. A., Enjalbert, B., Parrou, J. L., Francois, J. M. (2000). "The Saccharomyces cerevisiae YPR184w gene encodes the glycogen debranching enzyme." FEMS Microbiol Lett 193:105-110.11094287
  • Inoue, Y., Watanabe, K., Shimosaka, M., Saikusa, T., Fukuda, Y., Murata, K., Kimura, A. (1985). "Metabolism of 2-oxoaldehydes in yeasts. Purification and characterization of lactaldehyde dehydrogenase from Saccharomyces cerevisiae." Eur J Biochem 153:243-247.3908097
  • Xu, Z., Tsurugi, K. (2006). "A potential mechanism of energy-metabolism oscillation in an aerobic chemostat culture of the yeast Saccharomyces cerevisiae." FEBS J 273:1696-1709.16623706
  • Castrillo, J. I., Zeef, L. A., Hoyle, D. C., Zhang, N., Hayes, A., Gardner, D. C., Cornell, M. J., Petty, J., Hakes, L., Wardleworth, L., Rash, B., Brown, M., Dunn, W. B., Broadhurst, D., O'Donoghue, K., Hester, S. S., Dunkley, T. P., Hart, S. R., Swainston, N., Li, P., Gaskell, S. J., Paton, N. W., Lilley, K. S., Kell, D. B., Oliver, S. G. (2007). "Growth control of the eukaryote cell: a systems biology study in yeast." J Biol 6:4.17439666
Synthesis Reference:Li, Dalin; Ruan, Yi; Song, Wen; Wang, Yongjun. Improved process for producing glucose. Faming Zhuanli Shenqing Gongkai Shuomingshu (2003), 4 pp
External Links:
ResourceLink
CHEBI ID17634
HMDB IDHMDB00122
Pubchem Compound ID5793
Kegg IDC00031
ChemSpider ID23184483
FOODB IDFDB093715
WikipediaGlucose
BioCyc IDGLC

Enzymes

General function:
Involved in catalytic activity
Specific function:
Alpha,alpha-trehalose + H(2)O = 2 D-glucose
Gene Name:
NTH2
Uniprot ID:
P35172
Molecular weight:
89678.60156
Reactions
Alpha,alpha-trehalose + H(2)O → 2 D-glucose.
General function:
Involved in catalytic activity
Specific function:
Alpha,alpha-trehalose + H(2)O = 2 D-glucose
Gene Name:
ATH1
Uniprot ID:
P48016
Molecular weight:
136919.0
Reactions
Alpha,alpha-trehalose + H(2)O → 2 D-glucose.
General function:
Involved in catalytic activity
Specific function:
Alpha,alpha-trehalose + H(2)O = 2 D-glucose
Gene Name:
NTH1
Uniprot ID:
P32356
Molecular weight:
85878.5
Reactions
Alpha,alpha-trehalose + H(2)O → 2 D-glucose.
General function:
Involved in ATP binding
Specific function:
Main glucose phosphorylating enzyme. May play a regulatory role in both induction and repression of gene expression by glucose
Gene Name:
HXK2
Uniprot ID:
P04807
Molecular weight:
53942.0
Reactions
ATP + D-hexose → ADP + D-hexose 6-phosphate.
ATP + D-fructose → ADP + D-fructose 1-phosphate
General function:
Involved in ATP binding
Specific function:
ATP + D-hexose = ADP + D-hexose 6-phosphate
Gene Name:
HXK1
Uniprot ID:
P04806
Molecular weight:
53737.89844
Reactions
ATP + D-hexose → ADP + D-hexose 6-phosphate.
ATP + D-fructose → ADP + D-fructose 1-phosphate
General function:
Involved in ATP binding
Specific function:
Putative glucokinase involved in phosphorylation of aldohexoses and glucose uptake. Involved in sporulation. Required for the full activation of the early meiotic inducer IME1
Gene Name:
EMI2
Uniprot ID:
Q04409
Molecular weight:
55920.30078
Reactions
ATP + D-glucose → ADP + D-glucose 6-phosphate.
General function:
Involved in catalytic activity
Specific function:
Catalyzes the irreversible reduction of the cytotoxic compound methylglyoxal (MG) to (R)-lactaldehyde as an alternative to detoxification of MG by glyoxalase I GLO1. MG is synthesized via a bypath of glycolysis from dihydroxyacetone phosphate and is believed to play a role in cell cycle regulation and stress adaptation
Gene Name:
GRE2
Uniprot ID:
Q12068
Molecular weight:
38169.19922
Reactions
Lactaldehyde + NADP(+) → methylglyoxal + NADPH.
3-methylbutanol + NAD(P)+ → 3-methylbutanal + NAD(P)H + H+
General function:
Involved in ATP binding
Specific function:
Two isoenzymes, hexokinase-1 and hexokinase-2, can phosphorylate keto- and aldohexoses in yeast, whereas a third isoenzyme, GLK, is specific for aldohexoses. All glucose phosphorylating enzymes are involved in glucose uptake
Gene Name:
GLK1
Uniprot ID:
P17709
Molecular weight:
55376.89844
Reactions
ATP + D-glucose → ADP + D-glucose 6-phosphate.
General function:
Involved in oxidoreductase activity
Specific function:
Reduces the cytotoxic compound methylglyoxal (MG) to (R)-lactaldehyde similar to GRE2. MG is synthesized via a bypath of glycolysis from dihydroxyacetone phosphate and is believed to play a role in cell cycle regulation and stress adaptation. In pentose-fermenting yeasts, aldose reductase catalyzes the reduction of xylose into xylitol. The purified enzyme catalyzes this reaction, but the inability of S.cerevisiae to grow on xylose as sole carbon source indicates that the physiological function is more likely methylglyoxal reduction
Gene Name:
GRE3
Uniprot ID:
P38715
Molecular weight:
37118.5
Reactions
Alditol + NAD(P)(+) → aldose + NAD(P)H.
(R)-lactaldehyde + NADP(+) → methylglyoxal + NADPH.
General function:
Involved in catalytic activity
Specific function:
Hydrolysis of terminal, non-reducing (1->4)- linked alpha-D-glucose residues with release of alpha-D-glucose
Gene Name:
MAL32
Uniprot ID:
P38158
Molecular weight:
68141.79688
Reactions
General function:
Involved in hydrolase activity, hydrolyzing O-glycosyl compounds
Specific function:
Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1->3)-beta-D-glucans, releasing alpha-glucose
Gene Name:
EXG2
Uniprot ID:
P52911
Molecular weight:
63507.60156
Reactions
General function:
Involved in hydrolase activity, hydrolyzing O-glycosyl compounds
Specific function:
Probably involved in the processes of spore formation and contributes to ascospore thermoresistance by participating in the morphogenesis of ascospore walls. The enzyme may do this by modifying glucan linkages in the developing ascospore wall, thus strengthening it or lending it plasticity
Gene Name:
SPR1
Uniprot ID:
P32603
Molecular weight:
51809.10156
Reactions
General function:
Involved in catalytic activity
Specific function:
Hydrolysis of terminal, non-reducing (1->4)- linked alpha-D-glucose residues with release of alpha-D-glucose
Gene Name:
MAL12
Uniprot ID:
P53341
Molecular weight:
68093.70313
Reactions
General function:
Involved in hydrolase activity, hydrolyzing O-glycosyl compounds
Specific function:
Glucanases possibly play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme hydrolyzes both 1,3-beta- and 1,6- beta-linkages and even has beta-glucosidase activity. It could also function biosynthetically as a transglycosylase
Gene Name:
EXG1
Uniprot ID:
P23776
Molecular weight:
51310.5
Reactions
General function:
Involved in hydrolase activity, hydrolyzing O-glycosyl compounds
Specific function:
Glucanases possibly play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation and also function biosynthetically as a transglycosylase
Gene Name:
BGL2
Uniprot ID:
P15703
Molecular weight:
34118.30078
Reactions
General function:
Involved in hydrolase activity, hydrolyzing O-glycosyl compounds
Specific function:
Hydrolysis of terminal non-reducing beta-D- fructofuranoside residues in beta-D-fructofuranosides
Gene Name:
SUC1
Uniprot ID:
P10594
Molecular weight:
60569.89844
General function:
Involved in hydrolase activity, hydrolyzing O-glycosyl compounds
Specific function:
Hydrolysis of terminal non-reducing beta-D- fructofuranoside residues in beta-D-fructofuranosides
Gene Name:
SUC3
Uniprot ID:
P10595
Molecular weight:
8649.90039
General function:
Involved in catalytic activity
Specific function:
Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4- alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6- glucosidase in glycogen degradation
Gene Name:
GDB1
Uniprot ID:
Q06625
Molecular weight:
174970.0
Reactions
General function:
Involved in catalytic activity
Specific function:
Hydrolysis of terminal (1->4)-linked alpha-D- glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose
Gene Name:
SGA1
Uniprot ID:
P08019
Molecular weight:
61462.39844
Reactions
General function:
Involved in hydrolase activity, hydrolyzing O-glycosyl compounds
Specific function:
Hydrolysis of terminal non-reducing beta-D- fructofuranoside residues in beta-D-fructofuranosides
Gene Name:
SUC4
Uniprot ID:
P10596
Molecular weight:
60574.80078
General function:
Involved in hydrolase activity, hydrolyzing O-glycosyl compounds
Specific function:
Hydrolysis of terminal non-reducing beta-D- fructofuranoside residues in beta-D-fructofuranosides
Gene Name:
SUC5
Uniprot ID:
P10597
Molecular weight:
8649.90039
General function:
Involved in hydrolase activity, hydrolyzing O-glycosyl compounds
Specific function:
Hydrolysis of terminal non-reducing beta-D- fructofuranoside residues in beta-D-fructofuranosides
Gene Name:
SUC2
Uniprot ID:
P00724
Molecular weight:
60638.89844
Reactions
General function:
Involved in transferase activity, transferring hexosyl groups
Specific function:
Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol
Gene Name:
DIE2
Uniprot ID:
P50076
Molecular weight:
61807.0
Reactions
General function:
Involved in endo-1,3(4)-beta-glucanase activity
Specific function:
Involved in the dissoultion of the mother-daughter septum during cell separation
Gene Name:
DSE4
Uniprot ID:
P53753
Molecular weight:
121063.0
Reactions
General function:
Involved in catalytic activity
Specific function:
Preferentially hydrolyzes isomaltose, with little activity towards isomaltotriose or longer oligosaccharides. Does not hydrolyze maltose
Gene Name:
FSP2
Uniprot ID:
P53051
Molecular weight:
68591.0
Reactions
General function:
Involved in hydrolase activity, hydrolyzing O-glycosyl compounds
Specific function:
Hydrolysis of terminal non-reducing beta-D- fructofuranoside residues in beta-D-fructofuranosides
Gene Name:
SUC7
Uniprot ID:
P07635
Molecular weight:
11248.90039

Transporters

General function:
Involved in transmembrane transporter activity
Specific function:
Probable glucose transporter
Gene Name:
HXT9
Uniprot ID:
P40885
Molecular weight:
62857.19922
General function:
Involved in transmembrane transporter activity
Specific function:
GAL2 is a facilitated diffusion transporter required for both the high-affinity galactokinase-dependent and low-affinity galactokinase-independent galactose transport processes
Gene Name:
GAL2
Uniprot ID:
P13181
Molecular weight:
63625.39844
General function:
Involved in transmembrane transporter activity
Specific function:
Not Available
Gene Name:
STL1
Uniprot ID:
P39932
Molecular weight:
63531.19922
General function:
Involved in transmembrane transporter activity
Specific function:
Probable glucose transporter
Gene Name:
HXT11
Uniprot ID:
P54862
Molecular weight:
62732.19922
General function:
Involved in transmembrane transporter activity
Specific function:
Probable glucose transporter
Gene Name:
HXT10
Uniprot ID:
P43581
Molecular weight:
60661.5
General function:
Involved in transmembrane transporter activity
Specific function:
High-affinity glucose transporter
Gene Name:
HXT6
Uniprot ID:
P39003
Molecular weight:
62704.60156
General function:
Involved in transmembrane transporter activity
Specific function:
Probable glucose transporter
Gene Name:
HXT8
Uniprot ID:
P40886
Molecular weight:
63492.0
General function:
Involved in transmembrane transporter activity
Specific function:
High-affinity glucose transporter. Is only indispensable for growth on low glucose-containing media, because S.cerevisiae possesses other sugar transporters
Gene Name:
HXT2
Uniprot ID:
P23585
Molecular weight:
59840.19922
General function:
Involved in transmembrane transporter activity
Specific function:
Low-affinity glucose transporter. HXT1 is as well involved in the transport of mannose
Gene Name:
HXT1
Uniprot ID:
P32465
Molecular weight:
63260.89844
General function:
Involved in transmembrane transporter activity
Specific function:
Low-affinity glucose transporter
Gene Name:
HXT3
Uniprot ID:
P32466
Molecular weight:
62557.19922
General function:
Involved in transmembrane transporter activity
Specific function:
Low-affinity glucose transporter. Can also transport xylose
Gene Name:
HXT4
Uniprot ID:
P32467
Molecular weight:
63909.60156
General function:
Involved in transmembrane transporter activity
Specific function:
Probable glucose transporter
Gene Name:
HXT17
Uniprot ID:
P53631
Molecular weight:
62827.69922
General function:
Involved in transmembrane transporter activity
Specific function:
Probable glucose transporter
Gene Name:
HXT16
Uniprot ID:
P47185
Molecular weight:
62919.89844
General function:
Involved in transmembrane transporter activity
Specific function:
Probable glucose transporter
Gene Name:
HXT5
Uniprot ID:
P38695
Molecular weight:
66251.0
General function:
Involved in transmembrane transporter activity
Specific function:
Probable glucose transporter
Gene Name:
HXT13
Uniprot ID:
P39924
Molecular weight:
62733.60156
General function:
Involved in transmembrane transporter activity
Specific function:
Probable glucose transporter
Gene Name:
HXT15
Uniprot ID:
P54854
Molecular weight:
62930.89844
General function:
Involved in transmembrane transporter activity
Specific function:
High-affinity glucose transporter
Gene Name:
HXT7
Uniprot ID:
P39004
Molecular weight:
62734.60156